benthiavalicarb
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION

Description: A new fungicide active against Oomycetes fungal plant pathogens

Introduction: 2003

EC Directive 1107/2009 (repealing 91/414):
Status Annex 1
Dossier rapporteur/co-rapporteur Belgium
Date inclusion expires 31/07/2018

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Fungicide
Substance group Carbamate
Substance origin Synthetic
Mode of action Protective and curative action with residual effects, inhibits phospholipid biosynthesis
CAS RN 413615-35-7
EC number -
CIPAC number 744
US EPA chemical code -
Chiral molecule Yes
Chemical formula C15H18FN3O3S
SMILES c1cc(cc2sc(nc12)[C@H](NC(=O)[C@H](NC(O)=O)C(C)C)C)F
International Chemical Identifier (InChI) -
Structure diagram/image available? Yes
Molecular mass (g mol-1) 339.5
IUPAC Name [(S)-1-{[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]carbamoyl}-2-methylpropyl]carbamic acid
CAS Name [(1S)-1-[[[(1R)-1-(6-fluoro-2-benzothiazolyl)ethyl]amino]carbonyl]-2-methylpropyl]carbamic acid
Other status information -
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 40
Physical state White powder
Related substances & organisms

Formulations:
Property Value
Example manufacturers of products using this active
  • Certis
  • Kumiai Chemical Co
Example products using this active
  • Valbon
UK LERAP status LERAP Category B
Formulation and application details Usually supplied as the isopropyl variant and formulated as water dispersible granules for use as a spray.


ENVIRONMENTAL FATE

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) - - -
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting Point (oC) - - -
Boiling Point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P - - -
Log P - - -
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) - - -
Henry's law constant at 25oC (Pa m3 mol-1) - - -
Henry's law constant at 20oC (dimensionless) - - -
GUS leaching potential index - - -
SCI-GROW groundwater index (µg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value - - -
Note -
Potential for particle bound transport index - - -
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) - - -
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note: -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-Sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation Medium Estimated Maximum Occurrence Fraction 91/414 Relevancy
6-fluoro-2-hydroxybenzothiazole (Ref: KIF-230-M1) Soil     -
1-(6-fluoro-2-benzothiazol-2-yl)ethanol (Ref: KIF-230-M3) Soil     -
1-(6-fluoro-2-benzothiazolyl)ethylamine (Ref: KIF-230-M5) Soil     -

Other known metabolites:
Metabolite name and reference Aliases Formation Medium / Rate Estimated Maximum Occurrence Fraction Metabolising Enzymes
6-fluorobenzothiazol-2-yl methyl ketone
Note: Rat LD50 (oral) >2000; Koc = 297 		KF-230-M4 - - -
N-[1-(6-fluorobenzothiazol-2-yl)ethyl]acetamide KF-230-M8 - - -
6,6’-difluoro-2,2’-dibenzothiazole
Note: IMPURITY 		KF-230-I-6 IMPURITY - n/a
bis(2-amino-5-fluorophenyl) disulphide
Note: IMPURITY 		KF-230-I-12 IMPURITY - n/a


ECOTOXICOLOGY

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF - - -
CT50 (days) - -
Bioaccumulation potential - - -
Mammals - Acute oral LD50 (mg kg-1) - - -
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) - - -
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) - - -
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) - - -
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (µg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50product ha
EC50product ha
NOECproduct ha
% Effect 		- - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) - - -
Mammals - Dermal LD50 (mg kg-1 body weight) - - -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List II - -
Exposure Limits - - -
Exposure Routes Public No unacceptable risks to bystanders identified
Occupational Protective clothing should be worn
Possible risk from dermal exposure
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (µg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

General human health issues May cause allergic reaction
Possible liver & thyroid toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General Not explosive or oxidising
CLP classification 2013 -
EC Risk Classification Xi - Irritant: R43
N - Dangerous for the environment: R52, R53
EC Safety Classification S2
WHO Classification NL - Not listed
US EPA Classification (formulation) - - -
UN Number -
Waste disposal & packaging -


TRANSLATIONS

Language Name
English benthiavalicarb
French benthiavalicarbe
German Benthiavalicarb
Danish benthiavalicarb
Italian bentiavalicarb
Spanish bentiavalicarb
Greek -
Slovenian bentiavalikarb
Polish bentiawalikarb
Swedish -
Hungarian -
Dutch -
Record last updated: Saturday 18 May 2013
Contact: aeru@herts.ac.uk
© Copyright University of Hertfordshire