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ortosulfamuron (Ref: IR5878)
** orthosulfamuron ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

A herbicide currently being assessed for usage within in the EU. It is highly soluble in water, volatile and, based on its chemical properties, there is a high risk of ot leaching to groundwater. It tends not to be persistent in either soil or aquatic systems. It has a low mammalian toxicity and not thought to bioaccumulate. However, there are some concerns that it may be neurotoxic and be a reproduction/development toxin. It has a low to moderate toxicity to most biodiversity.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for orthosulfamuron

Descripción: Pre- and post-emergence rice herbicide active against grasses and some broad-leaved weeds

Ejemplos de plagas controladas: Sedges including flatsedge; Grass weeds including Barnyardgrass; Velvetleaf; Water-plantain; Mud-plantain; Sagittaria; False pimpernel

Ejemplos de aplicaciones: Rice

Eficacia y actividad: -

Availability status: Current

Introduction & key dates: circa 1998; 2007, Estados Unidos

CEE Regulación 1107/2009 ( 91/414):
Estado Not approved
Dossier rapporteur/co-rapporteur Italy
Date inclusion expires No aplicable
UE Candidatas a sustitución -
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Estados Unidos

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism -
Fórmula química C16H20N6O6S
Canonical SMILES CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) UCDPMNSCCRBWIC-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Herbicida
Grupo químico Pyrimidinylsulfonylurea
Minimum active substance purity 985mg/kg
Known relevant impurities EU dossier: Dichloromethane, maximum content 1 g/kg
Sustancias de origen Sintéticas
Modo de acción Systemic, systemic absorbed by foliage and roots and translocated, acetohydroxy acid synthase
CAS RN 213464-77-8
CEE número -
Número CIPAC 781
EPA américaine chimiques de code 108209
PubChem CID 11091168
Masa molecular (g mol-1) 424.44
PIN (Preferred Identification Name) 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}amino)-N,N-dimethylbenzamide
Nombre IUPAC 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea
Nombre CAS 2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]amino]-N,N-dimethylbenzamide
Otra información de estado -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not known
Herbicide Resistance Classification (WSSA) -
Insecticide Resistance Classification (IRAC) No aplicable
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance -
Estado físico Fine white, odourless powder
Related substances & organisms -

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Isagro USA
Example products using this active
  • Strada
  • Kelion
  • Percutio
Estado de UK LERAP No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as a water-dispersible granular formulation.


DESTINO AMBIENTAL

for orthosulfamuron

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 629 A5 Alto
Solubilidad - en solventes organicos en 20oC (mg l-1) 19500 A5 - Acetona -
3300 A5 - Acetato de etilo -
8300 A5 - Metanol -
56000 A5 - 1,2-Cloruro de metileno -
Punto de fusión (oC) 157 A5 -
Punto de ebullición (oC) Decomposes before boiling A5 -
El punto de degradación (oC) 185 A5 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 2.04 X 1001 Calculado -
Log P 1.31 A5 Bajo
Masa densidad (g ml-1)/Peso específico 1.48 L3 -
Disociación constante (pKa) at 25oC - - -
Nota:
Presión de vapor en 20oC (mPa) 0.112 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 7.6 X 10-05 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 6.58 Calculado Alta posibilidad de la lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 2.96 X 10-01 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Bajo
Maximum UV-vis absorption L mol-1 cm-1 Neutral soln.: 238nm=21100
Acidic soln.: 236nm=19500
Basic soln.: 241.0nm=27900
A5 -
Surface tension (mN m-1) 71.4 A5 at 22degC -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 12.5 A4 No persistente
DT50 (laboratorio en 20oC) 12.5 A4 No persistente
DT50 (campo) - - -
DT90 (laboratorio en 20oC) 41.5 A4 -
DT90 (campo) - - -
Endpoint de modelado DT50 - - -
Nota EU dossier (DAR) lab studies DT50 range 1.9-25 days, DT90 range 6.4-83 days; Isagro datasheet gives DT50 20-80 days; Other literature DT50 ranges 10-21 days
Dissipation rate RL50 on plant matrix Valor - - -
Nota -
Dissipation rate RL50 on and in plant matrix Valor - - -
Nota -
Acuoso fotólisis DT50 (días) en pH 7 Valor Estable A5 - -
Nota Not considered to be a significant route of degradation
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor 24.4 A5 No persistente
Nota pH and temperature sensitive: DT50 8 hours at pH 5, 228 days at pH 9, all at 25 degC; 0.4 hours at pH 4, 1.5 days at pH 7, 8 days at pH 9 all at 50 deg C.
Aqua-Sedimento DT50 (días) 30.3 A5 Moderado rápido
Fase de agua sola DT50 (días) 19.8 A5 Lento

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd 6.73 A5 Móvil moderado
Koc 352.5
Notas y rango EU dossier Kd range 6.003-8.568 mL/g, Koc range 249-550 mL/g, soil=4
Freundlich Kf 5.41 A5 -
Kfoc nd
1/n 0.871
Notas y rango EU dossier Kf range 3.763-6.662mL/g, Kfoc not calculated, 1/n range 0.749-0.920, soils=4
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
2-((dimethylamino)carbonyl)phenyl sulfamic acid (Ref: IR7863) This metabolite may cause environmental pollution, click here for further information Suelo   0.545   Major farction, Relevant
N-(4,6-dimethoxypyrimidin-2-yl) urea (Ref: IR7825) This metabolite may cause environmental pollution, click here for further information Suelo   0.570   Major fraction, Relevant
1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-(2,(2-dimethylcarbomyl)phenylsulfomoyl)urea (Ref: IR 8181) This metabolite may cause environmental pollution, click here for further information Suelo   0.224   Minor fraction, Not relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
1,-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-(2-(methylcarbomoyl)phenylsulfomoyl)urea N-desm-O-desm IR5878 Rat; Animals - -
2-amino-N,N-dimethylbenzamide DB amine Rat; Plants (rice, crops); Animals; Soil - -
2-sulfamoylamino-N,N-dimethylbenzamide DBS amide Rat; Plants (rice, crops); Soil - -
- Pyr-O-Glucur IR5878 Rat - -
- N-desmethyl IR5878 Rat; Animals - -
- Pyr-O-Glucur DOP urea Rat - -
(4,6-dimethoxy-5-sulfate pyrimidin-2-yl)urea Pyr-O-Sulf DOP Urea Rat; Animals - -
2-amino-N-methylbenzamide N-desmethyl DB amine Animals - -
- Pyr-OH DOP urea Animals - -


ECOTOXICOLOGÍA

for orthosulfamuron

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 1.0 A5 Bajo potencial
CT50 (días) No disponible -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A5 Rata Bajo
Mamíferos - a corto plazo NOEL (mg kg-1) - - -
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) > 2000 A5 Colinus virginianus Bajo
Birds - Short term dietary (LC50/LD50) - - -
Pez - agudo 96 hora LC50 (mg l-1) > 100 A5 Brachidanio rerio Bajo
Pez - Crónico 21 días NOEC (mg l-1) 6.1 A5 Pimephales promelas Moderado
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) > 100 A5 Daphnia magna Bajo
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 10 A5 Daphnia magna Moderado
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 66.9 A5 Chironomus riparius Bajo
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) 0.00033 A5 Lemna gibba, fronds Alto
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 13 A5 Anabaena flos-aquae Bajo
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) - - -
Abejas mielíferas Contacto aguda 48 hora LD50 (μg abeja-1) > 100 A5 Bajo
Oral aguda 48 hora LD50 (μg abeja-1) > 109.4 A5 Bajo
Modo desconocido aguda 48 hora LD50 (μg abeja-1) - - -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 1000 A5 Eisenia foetida Bajo
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) > 1000 A5 Eisenia foetida Bajo
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 - - -
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 - - -
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 0.507mg/Kg soil, 42 días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for orthosulfamuron

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A5 Rata Bajo
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 2.19 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.05 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.70 A5 Rabbit, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.05 A5 Rat, SF=300 -
Estudios den la absorción cutánea (%) 0.54-2.63 A4 concentration dependent -
Directivo 76/464 Sustancias Peligrosas - - -
Limites de exposiciones - - -
Exposure Routes Public Acceptable for proposed uses
Occupational Acceptable for proposed uses
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

Cuestiones generales de la salud humana May be absorbed through skin or inhalation
Possible liver, spleen and kideny toxicant
USEPA - some evidence to suggest possible human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
CLP classification 2013 Health: H361d
Environment: H400
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Reproduction risk category 3: R63
N - Dangerous for the environment: R50
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S2, S13, S20/21, S57, S60
Clasificación de OSM NL - No inscripto en la lista
US EPA Classification (formulation) No consensus across products or no products available - -
Número de las NU -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRADUCCIONES

for orthosulfamuron

Idioma Nombre
Inglés orthosulfamuron
Francés -
Alemán -
Danés -
Italiano -
Español ortosulfamuron
Griego -
Esloveno -
Polaco -
Sueco -
Húngaro -
Holandés -

Última actualización del registro: Thursday 31 May 2018
Contacto: aeru@herts.ac.uk