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carbofurano (Ref: OMS 864)
** carbofuran ** ENT 27164 ** FMC 10242 ** BAY 70143 ** D 1221 ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

Carbofuran is an insecticide and nematicide that is not approved for use in the EU. It is moderately soluble in water, is relatively volatile and, based on its chemical properties, has a high potential for leaching to groundwater. It is not persistent in soil but may persist in water under some conditions. Carbofuran has a high mammalian toxicity and a low potential for bioaccumulation. It is an endocrine disruptor and a probable reproduction/development intoxicant. It is highly toxic to birds and honeybees whilst having a moderate to high toxicity to most aquatic organisms. It is moderately toxic to earthworms.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for carbofuran

Descripción: A insecticide and nematicide for soil treatment to control soil and foliar pests. Also a pesticide transformation product

Ejemplos de plagas controladas: Spidermites; Nematodes; Aphids; Corn rootworms; Weevils; European corn borer; Beetles

Ejemplos de aplicaciones: Potatoes; Corn; Rice; Soybean; Fruit including citrus, grapes; Vegetables; Cotton; Alfalfa

Eficacia y actividad: -

Availability status: Current, Banned

Introduction & key dates: circa 1965

CEE Regulación 1107/2009 ( 91/414):
Estado Not approved
Dossier rapporteur/co-rapporteur Belgium
Date inclusion expires Expired
UE Candidatas a sustitución -
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, Estados Unidos

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism None
Fórmula química C12H15NO3
Canonical SMILES CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) DUEPRVBVGDRKAG-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)
¿Diagrama de estructura 2D / imagen disponible?

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Nombre Común Relación Vínculo
Carbofuran - Click here for the CCDC structure diagram

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Insecticide, Nematicide, Acaricide, Metabolite
Metabolite Type Suelo
Grupo químico Carbamate
Minimum active substance purity 960-980 g/kg
Known relevant impurities EU dossier - None declared
Sustancias de origen Sintéticas
Modo de acción Systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 1563-66-2
CEE número 216-353-0
Número CIPAC 276
EPA américaine chimiques de code 090601
PubChem CID 2566
Masa molecular (g mol-1) 221.26
PIN (Preferred Identification Name) 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
Nombre IUPAC 2,3-dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
Nombre CAS 2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
Otra información de estado Chemical subject to PIC regulations; Marine Pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 1A
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance Aphis gossypii
Myzus persicae
Plutella xylostella
Delia antiqua
plus others
Estado físico White crystalline powder
Related substances & organisms -

Puede ser un metabolito de
Padre/origen Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
furathiocarb Soil   0.800   Major fraction, Relevant
carbosulfan Soil   0.880   Major fraction, Relevant
benfuracarb Soil   0.846   Major fraction, Relevant

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • FMC Chemicals
  • Arysta LifeScience EAME
  • Nihon Nohyaku
  • Pillar International
Example products using this active
  • Furadan 5G
  • Diafuran 5G
  • Curaterr
  • Yaltox
  • Pillarfuran
Estado de UK LERAP No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually formulated as granules or microgranules for direct incorporation into the soil at drilling.


DESTINO AMBIENTAL

for carbofuran

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 322 A5 Moderado
Solubilidad - en solventes organicos en 20oC (mg l-1) 110 A5 - n-Heptano -
71700 A5 - Metanol -
61500 A5 - Acetato de etilo -
105200 A5 - Acetona -
Punto de fusión (oC) 153.1 A5 -
Punto de ebullición (oC) 254 A4 - -
El punto de degradación (oC) 276 A4 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 6.31 X 1001 Calculado -
Log P 1.8 A5 Bajo
Masa densidad (g ml-1)/Peso específico 1.26 A5 -
Disociación constante (pKa) at 25oC No aplicable A5 -
Nota: Ninguna disociación
Presión de vapor en 20oC (mPa) 0.08 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 5.0 X 10-05 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 2.28 Calculado Estado de transición
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 6.59 X 10-02 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Bajo
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 276nm = 2800, 290nm = 251; [Acidic & basic solution: No significant differences in spectrum A5 -
Surface tension (mN m-1) 54.7 A4 at 20oC -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 29 A5 No persistente
DT50 (laboratorio en 20oC) 12.8 A5 No persistente
DT50 (campo) 14 A5 No persistente
DT90 (laboratorio en 20oC) - - -
DT90 (campo) - - -
Endpoint de modelado DT50 - - -
Nota EU dossier Lab studies DT50 range 5.7-22.7 days, field studies DT50 range 1.3-27 days; Other sources DT50 30-60 days (L3)
Dissipation rate RL50 on plant matrix Valor 4.9 R4 -
Nota Published literature RL50 range 1.9-11.5 days, 6 field crops, various matrices, n=7
Dissipation rate RL50 on and in plant matrix Valor 6.8 R4 -
Nota Published literature RL50 range 2.3-12.5 days, 6 field crops, various matrices, n=7
Acuoso fotólisis DT50 (días) en pH 7 Valor 71 A5 Estable
Nota -
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor 37 A5 Persistente moderado
Nota pH sensitive: stable at pH 4, DT50 28-46 days at pH 7, 0.1 day at pH 9
Aqua-Sedimento DT50 (días) 9.7 A5 Rápido
Fase de agua sola DT50 (días) 6.1 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - - -
Koc -
Notas y rango -
Freundlich Kf 1.14 A5 Móvil moderado
Kfoc 86.5
1/n 0.89
Notas y rango EU dossier kf range 0.096-4.77 mL/g, Kfoc range 9.7-433 mL/g, 1/n range 0.725-1.01, Soils=14
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
3-hydroxycarbofuran Suelo   0.008   Minor fraction, Relevant
3-ketocarbofuran Suelo   0.062   Minor fraction, Relevant
2,3.dihydro-2,2-diemethyl-7-benzofuranol (Ref: NIA 10272 ) Suelo   0.090   Minor fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
- 3-keto-7-phenol Rat - -
- N-OH methylcarbofuran Rat (Urinary) - -
- 3-OH-N-OH methylcarbofuran Rat (Urinary) - -


ECOTOXICOLOGÍA

for carbofuran

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 12 A5 Whole fish Bajo potencial
CT50 (días) 0.5 -
Mamíferos - Agudos oral LD50 (mg kg-1) 7 A5 Rata Alto
Mamíferos - a corto plazo NOEL (mg kg-1) 0.1 A5 Rata, 2 año Alto
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) 0.71 A5 Anas platyrhynchos Alto
Birds - Short term dietary (LC50/LD50) 1.6 mg kg-1 bw/día A5 Anas platyrhynchos -
Pez - agudo 96 hora LC50 (mg l-1) 0.18 A5 Lepomis macrochirus Moderado
Pez - Crónico 21 días NOEC (mg l-1) 0.0022 A5 Oncorhynchus mykiss, 28 día Growth Alto
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 0.0094 A5 Daphnia magna Alto
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.008 A5 Daphnia magna Alto
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) 0.016 F3 Chironomus riparius, 1 día Alto
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 0.004 A5 Chironomus riparius Alto
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 6.5 A5 Pseudokirchneriella subcapitata Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) 3.2 Q2 Unknown species Bajo
Abejas mielíferas (Apis spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 0.036 A5 Alto
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 0.05 A5 Alto
Modo desconocido aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Abejorros (Bombus spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Abejas albañiles (Osmia spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Otros polinizadores (1) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Otros polinizadores (2) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Lombrices - Agudos 14 día LC50 (mg kg-1) 224 A5 Eisenia foetida Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) > 0.84 A5 Eisenia foetida Moderado
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 2.68 LD50
A5 Aphidius rhopalosiphi, adult
-
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 3.65 LD50
A5 Typhlodromus pyri, protonymph
-
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: -20% effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 16 mg Diafuran SG product/kg soil, día 42
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for carbofuran

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) 7 A5 Rata Alto
Mammals - Dermal LD50 (mg kg-1 body weight) > 1000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.05 A5 Rat -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.00015 A5 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.00015 A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.0003 A2 Rat, SF=100 -
Estudios den la absorción cutánea (%) 3.0-10 A5 concentration dependent -
Directivo 76/464 Sustancias Peligrosas - - -
Exposure Routes Public Bystander exposure risk is low due to formulation of products and soil incorporation
Occupational Negligible risk to operators and other farm works due to dust-free formulation and application method
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards Non-statutory WHO drinking water guideline 0.007 mg/L UK EA QS database, 2018 -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotóxico Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A2; D2; C3; D3; E3

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

Cuestiones generales de la salud humana May cause testicular degeneration
May be fatal if swallowed, inhaled, or absorbed through skin
Endocrine issues - Increase of progesterone, cortisol and estradiol levels
Clave: Genotoxicidad
A: Aberración cromosómica (base de datos EFSA)
B: Daño/reparación del ADN (base de datos EFSA)
C: Mutación genética (base de datos EFSA)
D: Mutación del genoma (base de datos EFSA)
E: Tipo de genotoxicidad no especificada (fuente de datos diversos)
0: Sin datos
1: Positivo
2: Resultados mixtos/ambiguos
3: Negativo
Clave: Otro
: Sí, se sabe que causa un problema
: No, sabe no causar un problema
: Posiblemente, estado no identificado
- : Datos no encontrados

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
Corrosive
Containers may explode in heat of fire
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H300, H330
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases T+ - Very toxic: R26/28
N - Dangerous for the environment: R50, R53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S1/2, S36/37, S45, S60, S61
Clasificación de OSM Ib - Peligroso alto
Número de las NU 2757
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group I (great danger)


TRADUCCIONES

for carbofuran

Idioma Nombre
Inglés carbofuran
Francés carbofuran
Alemán Carbofuran
Danés carbofuran
Italiano carbofuran
Español carbofurano
Griego carbofuran
Esloveno karbofuran
Polaco karbofuran
Sueco -
Húngaro karbofuran
Holandés carbofuraan

Última actualización del registro: Tuesday 25 June 2019
Contacto: aeru@herts.ac.uk