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8-hydroxyquinoline
** 8-hydroxyquinoline ** 8-hydroxychinoline ** hydroxybenzopyridine ** quinophenol ** 1-azanaphthalene-8-ol ** HQ ** oxyquinoline ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

An EU approved fungicide with applications mainly in horticulture. It has a high aqueous solubility, moderate volatility and a low risk of leaching to groundwater. It is not persistent in soil systems but may be persistent in aqueous systems under some conditions. It has a moderate oral rat toxicity and may have some negative impacts on human health. it is a potential mutagen and may cause damage to reproduction and development. It is toxic to birds and moderately toxic to most aquatic life, honeybees and earthworms.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for 8-hydroxyquinoline

Descripción: A quinoline preventative and curative fungicide used to control various pathogens on vines and other crops

Ejemplos de plagas controladas: Grey mould; Downy mildew; Fusarium; Verticillium

Ejemplos de aplicaciones: Vines; Tomatoes; Hops

Eficacia y actividad: -

Availability status: Current

Introduction & key dates: circa 1940

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur Spain/Netherlands
Date inclusion expires 31/12/2021
UE Candidatas a sustitución No
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism -
Fórmula química C9H7NO
Canonical SMILES C1=CC2=C(C(=C1)O)N=CC=C2
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) MCJGNVYPOGVAJF-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
¿Diagrama de estructura 2D / imagen disponible?

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Nombre Común Relación Vínculo
8-hydroxyquinoline - Click here for the CCDC structure diagram

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Fungicide, Bactericide
Grupo químico Quinoline
Minimum active substance purity 99%, 990 g/Kg
Known relevant impurities EU dossier: None declared
Sustancias de origen Sintéticas
Modo de acción Systemic, preventative and curative - chelates various metals required by micro-organisms for their metabolism.
CAS RN 148-24-3
CEE número 205-711-1
Número CIPAC 677
EPA américaine chimiques de code 059803
PubChem CID 1923
Masa molecular (g mol-1) 145.16
PIN (Preferred Identification Name) 8-quinolinol
Nombre IUPAC 8-quinolinol
Nombre CAS 8-quinolinol
Otra información de estado Potential groundwater pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) No aplicable
Fungicide Resistance Classification (FRAC) Not known
Examples of recorded resistance -
Estado físico Pure substance (99.9%) is a crystalline solid with characteristic odour and slightly yellowish colour
Related substances & organisms -

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Probelte SA
Example products using this active
  • Beltanol-L
Estado de UK LERAP No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as a soluble concentrate and often applied by drip irrigation.


DESTINO AMBIENTAL

for 8-hydroxyquinoline

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 633 A5 Alto
Solubilidad - en solventes organicos en 20oC (mg l-1) 10000 A4 - n-Heptano -
250000 A4 - 1,2-Dichloroethane -
250000 A4 - Acetona -
250000 A4 - Acetato de etilo -
Punto de fusión (oC) 73.1 A5 -
Punto de ebullición (oC) 265.6 A5 -
El punto de degradación (oC) - - -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 8.22 X 1001 Calculado -
Log P 1.915 A5 - @ 22 DegC Bajo
Masa densidad (g ml-1)/Peso específico 1.03 Q3 -
Disociación constante (pKa) at 25oC 4.88 A5 -
Nota: pKa(2) = 9.45
Presión de vapor en 20oC (mPa) 0.0670 A4 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 1.83 X 10-03 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 0.39 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 5.35 X 10-03 Calculado -
Nota Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Bajo
Maximum UV-vis absorption L mol-1 cm-1 pH 1.5: 251.5nm = 42971.4, 357nm = 1657.1; [pH 6.9: 239.5nm = 34832.1, 306nm = 2603.6; [pH 10.1: 253nm = 29096.4, 333.5nm = 2521.4 A5 -
Surface tension (mN m-1) 71.2 A5 at 20 degC, 99.9% -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 0.3 Click here to see a warning relating to modelling and this active substance A5 No persistente
DT50 (laboratorio en 20oC) 0.3 A5 No persistente
DT50 (campo) - - -
DT90 (laboratorio en 20oC) 19.6 A5 -
DT90 (campo) - - -
Endpoint de modelado DT50 - - -
Nota EU dossier Lab studies DT50 range 0.0002-0.9 days, DT90 range 0.3-37.7 days
Dissipation rate RL50 on plant matrix Valor - - -
Nota -
Dissipation rate RL50 on and in plant matrix Valor - - -
Nota -
Acuoso fotólisis DT50 (días) en pH 7 Valor - - -
Nota -
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor Estable A5 -
Nota -
Aqua-Sedimento DT50 (días) 230 A5 Lento
Fase de agua sola DT50 (días) 1.0 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - - -
Koc -
Notas y rango -
Freundlich Kf 1105.6 A5 No Móvil
Kfoc 55460
1/n 1.06
Notas y rango EU dossier Kf range 286-2965 mL/g, Kfoc range 12796-111459 mL/g, 1/n range 0.66-1.39, Soils=5
pH senbsibilidad No


ECOTOXICOLOGÍA

for 8-hydroxyquinoline

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) Low risk A5 Based on LogP < 3 Bajo potencial
CT50 (días) - -
Mamíferos - Agudos oral LD50 (mg kg-1) 790 A5 Rata Moderado
Mamíferos - a corto plazo NOEL (mg kg-1) - - -
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) 311 A5 Coturnix japonica Moderado
Birds - Short term dietary (LC50/LD50) > 5000 mg kg feed-1 A5 Coturnix japonica -
Pez - agudo 96 hora LC50 (mg l-1) 2.00 A5 Oncorhynchus mykiss Moderado
Pez - Crónico 21 días NOEC (mg l-1) > 0.0079 A4 Oncorhynchus mykiss, 28 días Alto
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 3.32 A5 Daphnia magna Moderado
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) - - -
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 124.92 A5 Chironomus riparius Bajo
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 1.42 A5 Desmodesmus subspicatus, /i> growth rate Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) - - -
Abejas mielíferas Contacto aguda 48 hora LD50 (μg abeja-1) > 100 A5, as HQ-sulphate Bajo
Oral aguda 48 hora LD50 (μg abeja-1) > 68.6 A5, as HQ-sulphate Moderado
Modo desconocido aguda 48 hora LD50 (μg abeja-1) - - -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 204.3 A5 Eisenia foetida, as sulphate, corr Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) > 417.3 A5 Eisenia foetida, as sulphate, corr Bajo
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 16 >, as L/ha
A5 Typhlodromus pyri
-
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 16 >, as L/ha
A5 Aphidius rhopalosiphi
-
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 43 mg ha-1, 28días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for 8-hydroxyquinoline

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) 790 A5 Rata Moderado
Mammals - Dermal LD50 (mg kg-1 body weight) > 10000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.05 A5 Rabbit, SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.05 A5 Rabbit, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.05 A5 Rabbit, SF=100 -
Estudios den la absorción cutánea (%) 100 A3 default -
Directivo 76/464 Sustancias Peligrosas - - -
Limites de exposiciones - - -
Exposure Routes Public Negligible if used as prescribed
Occupational PPE/PPC advised
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

Cuestiones generales de la salud humana May cause irreversible eye damage
Possible kidney & spleen toxicant
Allergen & skin sensitiser

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
Prevent generation of dust
CLP classification 2013 Health: H360D, H301, H308, H317
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Xi - Irritant: R36/R37/R38
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases -
Clasificación de OSM NL - No inscripto en la lista
US EPA Classification (formulation) III - Caution - Slightly toxic
Número de las NU -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRADUCCIONES

for 8-hydroxyquinoline

Idioma Nombre
Inglés 8-hydroxyquinoline
Francés -
Alemán 8-Hydroxy-chinolin
Danés -
Italiano -
Español -
Griego -
Esloveno -
Polaco -
Sueco -
Húngaro -
Holandés -

Última actualización del registro: Wednesday 31 October 2018
Contacto: aeru@herts.ac.uk