Seleccione la Opción
Inicio
A a Z Indice
Búsqueda
Términos y Condiciones
Información de Asistencia
Compras y Servicios
GET ADDITIONAL DATA HERE!

isopyrazam (Ref: SYN 520453)
** isopyrazam ** A15149W ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for isopyrazam

Descripción: A novel persisent and broad spectrum fungicide for the cereals and some other crops

Ejemplos de plagas controladas: Septoria tritici, Rusts, Black sigatoka (banana leaf spot disease); Scab; Powder mildews; Alternaria

Ejemplos de aplicaciones: Cereals including winter & spring barley, wheat; Bananas; vegetables, Ornamentals; Various speciality crops

Eficacia y actividad: Barley/Rhynchosporium=Moderate; Barley/Mildew=Low; Barley/Rust=Moderate; Barley/Net blotch=Moderate; Barley/Ramularia=Moderate

Availability status: Current

Introduction & key dates: 2008

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires 31/03/2023
UE Candidatas a sustitución Yes - two 'Persistent-Bioaccumulative-Toxic' criteria
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism A chiral molecule. The technical material is an isomeric mixture of the syn-isomer (approx. 70-100%) and the anti-isomer (approx. 0-30%)
Fórmula química C20H23F2N3O
Canonical SMILES CC(C)C1C2CCC1C3=C2C=CC=C3NC(=O)C4=CN(N=C4C(F)F)C
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) XTDZGXBTXBEZDN-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)/f/h23H
¿Diagrama de estructura 2D / imagen disponible?

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Nombre Común Relación Vínculo
Isopyrazam Unstated isomer Click here for the CCDC structure diagram

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Fungicide
Grupo químico Pyrazole
Minimum active substance purity >920 g/kg
Known relevant impurities EU dossier: none declared
Sustancias de origen Sintéticas
Modo de acción Protectant, foliar absorption, translocates, inhibits respiration and spore germination and so germ tude elongation - a succinate dehydrogenase inhibitor
CAS RN 881685-58-1
CEE número -
Número CIPAC -
EPA américaine chimiques de code 129222
PubChem CID 25271089
Masa molecular (g mol-1) 359.4
PIN (Preferred Identification Name) mixture of 2 syn-isomers rac-3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide and 2 anti-isomers rac-3-(difluoromethyl)-1-methyl-N-[(1R,4S,9S)-9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide
Nombre IUPAC mixture of 2 isomers 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9RS)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and 2 aisomers 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9SR)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide
Nombre CAS 3-(difluoromethyl)-1-methyl-N-[1,2,3,4-tetrahydro-9-(1-methylethyl)-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide
Otra información de estado Marine pollutant; PAN listed Highly Hazardous Chemical
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) No aplicable
Fungicide Resistance Classification (FRAC) 7
Examples of recorded resistance None identified
Estado físico Off-white coloured solid
Related substances & organisms

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Syngenta Crop Protection
Example products using this active
  • Bontima
  • Seguris Flexi
  • Zulu
  • Reflect 125 EC
Estado de UK LERAP Buffer probably required in UK - see product label
Formulation and application details Usually supplied as an emulsifiable concentrate and used as a foliar spray.


DESTINO AMBIENTAL

for isopyrazam

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 0.55 A4 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 314000 A5 - Acetona -
303111 A5 - Cloruro de metileno -
1170 A5 - Hexano -
77100 A5 - Tolueno -
Punto de fusión (oC) 137 A4 -
Punto de ebullición (oC) 267 A4 -
El punto de degradación (oC) 261 A4 -
Punto de inflamación (oC) - - -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 1.78 X 1004 Calculado -
Log P 4.25 A4 Alto
Masa densidad (g ml-1)/Peso específico - - -
Disociación constante (pKa) at 25oC No aplicable A5 -
Nota: Ninguna disociación
Presión de vapor en 20oC (mPa) 1.3 X 10-04 A4 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 1.14 X 10-04 A4 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 1.47 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 4.01 X 10-02 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Alto
Maximum UV-vis absorption L mol-1 cm-1 225nm = 169771 isomer mean; [295nm = 6712.3 isomer mean A5 -
Surface tension (mN m-1) 63.1 A5 -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 244 A5 Persistente
DT50 (laboratorio en 20oC) 244 A5 Persistente
DT50 (campo) 72 A5 Persistente moderado
DT90 (laboratorio en 20oC) 811 A5 -
DT90 (campo) 543 A5 -
Endpoint de modelado DT50 - - -
Nota EU dossier DT50 Lab studies range 29.8-976 days, DT90 range 132-1000 days; Field studies DT50 range 9.11-173 days, DT90 range 63.5-2089 days
Dissipation rate RL50 on plant matrix Valor - - -
Nota -
Dissipation rate RL50 on and in plant matrix Valor - - -
Nota -
Acuoso fotólisis DT50 (días) en pH 7 Valor 54.3 A5 Estable
Nota Natural light, 30-50 DegN, 12hr day length
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor Estable A5 -
Nota Stable at all environmentally pH's
Aqua-Sedimento DT50 (días) 628 A5 Estable
Fase de agua sola DT50 (días) 2.3 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - - -
Koc -
Notas y rango -
Freundlich Kf 30.3 A5 Móvil un poco
Kfoc 2416
1/n 0.942
Notas y rango EU dossier Kf range 11.56-51.83 mL/g, Kfoc range 1732-2491 mL/g, 1/n range 0.92-0.97, Soils=6
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
3-(difluoromethyl)-1-methyl-N-((1R,4S,9R)-1,2,3,4,-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl)pyrazsaole-4-carboxamide (Ref: CSCD459488) This metabolite may cause environmental pollution, click here for further information Suelo   0.236   Major fraction, Relevant
3-(difluoromethyl)-1H-pyrazole-4-carboxylic acid (Ref: CSCD465008) This metabolite may cause environmental pollution, click here for further information Suelo   0.115   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid CSAA798670 Soil 0.054 -
dihydroxy isopyrazam CDCD656800 Hens; Animal (Milk, Tissue) - -
3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide CSCC210616 Soil 0.080 -


ECOTOXICOLOGÍA

for isopyrazam

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) - - -
CT50 (días) - -
Mamíferos - Agudos oral LD50 (mg kg-1) 2000 A5 Rata Moderado
Mamíferos - a corto plazo NOEL (mg kg-1) - - -
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) > 2000 A5 Colinus virginianus Bajo
Birds - Short term dietary (LC50/LD50) 5620 mg kg-1 Feed A5 Colinus virginianus -
Pez - agudo 96 hora LC50 (mg l-1) 0.0258 A5 Cyprinus carpio Alto
Pez - Crónico 21 días NOEC (mg l-1) 0.00287 A5 Pimephales promelas, 28día Alto
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 0.044 A5 Daphnia magna Alto
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.013 A5 Daphnia magna Moderado
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 1.0 A5 Chironomus riparius Moderado
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) > 0.5 A5 Lemna gibba Moderado
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 2.2 A5 Pseudokirchneriella subcapitata Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) - - -
Abejas mielíferas Contacto aguda 48 hora LD50 (μg abeja-1) > 200 A5 Bajo
Oral aguda 48 hora LD50 (μg abeja-1) > 192.3 A5 Bajo
Modo desconocido aguda 48 hora LD50 (μg abeja-1) - - -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 500 A5 Eisenia foetida, corr Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) 60 A5 Eisenia foetida, 56 días Moderado
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 174.75 A5 Typhlodromus pyri -
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 41.2 A5 Aphidius rhopalosiphi -
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 1.67 mg kg-1 soil, 28 días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for isopyrazam

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class - - -
Mamíferos - Agudos oral LD50 (mg kg-1) 2000 A5 Rata Moderado
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.28 A5 Rat, 4 hr -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.03 A5 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.2 A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.05 A5 -
Estudios den la absorción cutánea (%) 1.0 A5 -
Directivo 76/464 Sustancias Peligrosas - - -
Limites de exposiciones - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

Cuestiones generales de la salud humana Possible liver toxicant
USEPA - probable human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code 9
CLP classification 2013 Health: H317, H361
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Xn - Harmful: R22, R43
N - Dangerous for the environment: R50/53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S36/37, S60
Clasificación de OSM NL - No inscripto en la lista
US EPA Classification (formulation) - -
Número de las NU 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRADUCCIONES

for isopyrazam

Idioma Nombre
Inglés isopyrazam
Francés isopyrazam
Alemán Isopyrazam
Danés -
Italiano -
Español -
Griego -
Esloveno -
Polaco -
Sueco -
Húngaro -
Holandés -

Última actualización del registro: Wednesday 31 October 2018
Contacto: aeru@herts.ac.uk