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acrinatrina (Ref: RU38702)
** acrinathrin ** acrinathrine ** AE F076003 ** HOE 76003 ** NU 702 ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

Acrinathrin is a synthetic pyrethroid that has a high insecticidal activity against a range of insects including mites and which is approved for use in the EU. It has a low aqueous solubility, is semi-volatile and, based on its chemical properties, should not leach. Laboratory studies suggest it is moderately persistent in soils but will rapid degrade in aqueous systems. It has a low toxicity to humans but there is some concern that it may bio-accumulate. Acrinathrin is highly toxic to bees and most aquatic species, moderately toxic to birds and earthworms.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for acrinathrin

Descripción: A pyrethroid ester insecticide and acaricide effective against a range of phytophagous mites and other insects

Ejemplos de plagas controladas: Psyllid; Two-spotted spider mites; Thrips; Leafminers; Aphids

Ejemplos de aplicaciones: Potatoes; Tomatoes; French and runner beans

Eficacia y actividad: -

Availability status: Current

Introduction & key dates: 1990, France

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur France
Date inclusion expires 31/12/2021
UE Candidatas a sustitución No
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism Acrinathrin contains three chiral centres and one double bond, giving a total of 15 potential isomers other than acrinathrin (8 enantiomeric pairs where acrinathrin is one isomer of an enantiomeric pair).
Fórmula química C26H21F6NO5
Canonical SMILES CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=CC(=O)OC(C(F)(F)F)C(F)(F)F)C
Isomeric SMILES CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C
International Chemical Identifier Key (InChIKey) YLFSVIMMRPNPFK-WEQBUNFVSA-N
International Chemical Identifier (InChI) InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/t18-,19+,21-/m0/s1
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Insecticide, Acaricide
Grupo químico Pyrethroid
Minimum active substance purity 970 g/kg
Known relevant impurities EU dossier - 1,3-dicyclohexylurea <2mg/kg
Sustancias de origen Sintéticas
Modo de acción Contact and stomach action. Neurotoxin.
CAS RN 101007-06-1
CEE número -
Número CIPAC 678
EPA américaine chimiques de code -
PubChem CID 6436606
Masa molecular (g mol-1) 541.44
PIN (Preferred Identification Name) (S)-cyano(3-phenoxyphenyl)methyl (1R,3S)-3-{(1Z)-3-[(1,1,1,3,3,3-hexafluoropropan-2-yl)oxy]-3-oxoprop-1-en-1-yl}-2,2-dimethylcyclopropane-1-carboxylate
Nombre IUPAC (S)-α-cyano-3-phenoxybenzyl (Z)-(1R)-cis-2,2-dimethyl-3-[2-(2,2,2-trifluoro-1-trifluoromethylethoxycarbonyl)vinyl]cyclopropanecarboxylate
Nombre CAS (S)-cyano(3-phenoxyphenyl)methyl (1R,3S)-2,2-dimethyl-3-[(1Z)-3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylate
Otra información de estado -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 3
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance Frankliniella occidentalis
Tetranychus urticae
Estado físico White to beige coloured powder
Related substances & organisms -

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Cheminova
Example products using this active
  • Rufast
Estado de UK LERAP No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details An oil-water emulsion concentrate usually diluted with water and applied as a foliar spray.


DESTINO AMBIENTAL

for acrinathrin

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 0.0022 A5 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 400000 A5 - Xileno -
17500 A5 - n-Hexano -
61400 A4 - Etanol -
700000 A5 - Acetona -
Punto de fusión (oC) 81 A5 -
Punto de ebullición (oC) Decomposes before boiling A5 -
El punto de degradación (oC) 230 A5 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 2.00 X 1006 Calculado -
Log P 6.3 A5 Alto
Masa densidad (g ml-1)/Peso específico - - -
Disociación constante (pKa) at 25oC No aplicable A5 -
Nota: Ninguna disociación
Presión de vapor en 20oC (mPa) 4.40 X 10-05 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 1.80 X 10-02 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index -0.92 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 5.35 X 10-03 Calculado -
Nota Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Mediano
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution 291nm = 466; [Acidic solution 291nm = 642; [Basic solution 308nm = 1760 A5 -
Surface tension (mN m-1) - - -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 39.2 A4 Persistente moderado
DT50 (laboratorio en 20oC) 40.6 A5 Persistente moderado
DT50 (campo) 22 R3 No persistente
DT90 (laboratorio en 20oC) 208.5 A5 -
DT90 (campo) - - -
Endpoint de modelado DT50 - - -
Nota EU dossier lab studies DT50 range: 8.5-111.4 days, DT90 range 28.2-887.1 days; General literature gives DT50 range 9-37 days
Dissipation rate RL50 on plant matrix Valor - - -
Nota -
Dissipation rate RL50 on and in plant matrix Valor 2.6 R4 -
Nota Published literature RL50 range 1.2-6.9 days, 3 undercover crops, various matrices, n=4
Acuoso fotólisis DT50 (días) en pH 7 Valor 2.3 A5 Moderado rápido
Nota -
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor Estable W4 -
Nota Stable in acid media. Hydrolysis becomes more important as pH and temp increases: DT50 30 days at pH 7, 30 degC, 15 days at pH 9, 20 degC, <2 days pH9, 37 degC
Aqua-Sedimento DT50 (días) 18.6 A5 Rápido
Fase de agua sola DT50 (días) 6.5 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd 744 A5 No Móvil
Koc 48231
Notas y rango EU dossier Kd range 302-1350 mL/g, Koc range 24108-90061 mL/g, Soils=5
Freundlich Kf - - -
Kfoc -
1/n -
Notas y rango -
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
cis-des-hexafluoroisopropyl acrinathrin (Ref: DP-A) Suelo   0.097   Major fraction, Relevant
(2Z)-3-(3-((2-amino-2-oxo-1-(3-phenoxyphenyl)ethoxy)carbonyl)-2,2-dimethylcyclopropyl)prop-2-enoic acid This metabolite may cause environmental pollution, click here for further information Suelo   0.105   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
unknown
Nota: Minor metabolite
3-PBAc Soil; Surface water Soil: 0.076 -
A-A
Nota: DT50 7.4 days; Koc 88880
- Soil 0.057 -
alphaR A-A - Soil 0.029 -
3-PBAld - Groundwater - -
1,3-dicyclohexylurea
(Ref: AEB007816)
- Impurity - -
cyclopropyl-di-acid
(Ref: RU 50158)
Nota: Minor metabolite
DP-DPB-A Animal (Urinary); Plant Soil: 0.076 -


ECOTOXICOLOGÍA

for acrinathrin

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 538 A5 Umbral de importancia
CT50 (días) 3 -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A4 Rata Bajo
Mamíferos - a corto plazo NOEL (mg kg-1) 2.4 L3 Rata Alto
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) > 2000 A5 Anas platyrhynchos Bajo
Birds - Short term dietary (LC50/LD50) 1000 mg kg feed-1 A5 Anas platyrhynchos -
Pez - agudo 96 hora LC50 (mg l-1) 0.0061 A5 Oncorhynchus mykiss Alto
Pez - Crónico 21 días NOEC (mg l-1) 0.00043 A5 Cyprinus carpio Alto
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 0.000022 A5 Daphnia magna Alto
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.0000032 A5 Daphnia magna Alto
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 0.000031 A5 Chironomus riparius, whole system Alto
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants 888 A5 Mungbean
Vegetative vigour, ER50
as g/ha
-
> 1000 A5 Mungbean
Seedling emergence, ER50
as g/ha
-
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 0.0035 A5 Selenastrum capricornutum Alto
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) - - -
Abejas mielíferas (Apis spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 0.084 A5 Alto
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 0.077 A5 Alto
Modo desconocido aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Abejorros (Bombus spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Abejas albañiles (Osmia spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Otros polinizadores (1) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Otros polinizadores (2) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 100 A5 Eisenia foetida Moderado
Lombrices - Crónicos NOEC, reproducción (mg kg-1) 1.6 A5 Eisenia foetida Moderado
Other soil macro-organisms Agudos LC50 (mg kg-1) - - -
Crónicos NOEC (mg kg-1) 1.0 A5 Folsomia candida, 28d -
Otro arthropoda (1) LR50 g ha-1 0.046 Mortalidad
A5 Alphidius rhopalosiphi
-
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 0.006 Mortalidad
A5 Typhlodromus pyri
-
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 1 mg kg-1 soil, 28 días
-
Mesocosm study data NOEAEC mg l-1 0.000026 A5 Micro-invertebrates NOEC -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for acrinathrin

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A4 Rata Bajo
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 1.21 A5 Rat, 4 hr (whole body) -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.01 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.01 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.007 A5 Rat, SF=100 -
Estudios den la absorción cutánea (%) 2.0-8.3 A5 concentration dependent -
Directivo 76/464 Sustancias Peligrosas Lista II - -
Exposure Routes Public No unacceptable risks to bystanders identified as long as access to spray area prohibited during spraying
Occupational Risks identified - protective clothing and equipment advised
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotóxico Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B3; C3; D0; E3

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

Cuestiones generales de la salud humana May cause diarrhoea and vomiting if ingested
Possible kidney and blood toxicant
Clave: Genotoxicidad
A: Aberración cromosómica (base de datos EFSA)
B: Daño/reparación del ADN (base de datos EFSA)
C: Mutación genética (base de datos EFSA)
D: Mutación del genoma (base de datos EFSA)
E: Tipo de genotoxicidad no especificada (fuente de datos diversos)
0: Sin datos
1: Positivo
2: Resultados mixtos/ambiguos
3: Negativo
Clave: Otro
: Sí, se sabe que causa un problema
: No, sabe no causar un problema
: Posiblemente, estado no identificado
- : Datos no encontrados

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H332
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Carcinogen category 3: R40
Xn - Harmful: R21, R20
N - Dangerous for the environment: R50/53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S1/2, S24, S36/37, S45, S46, S60, S61
Clasificación de OSM U - Es poco probable que presente un riesgo agudo
Número de las NU Usually 3077
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRADUCCIONES

for acrinathrin

Idioma Nombre
Inglés acrinathrin
Francés acrinathrine
Alemán Acrinathrin
Danés acrinathrin
Italiano acrinatrina
Español acrinatrina
Griego -
Esloveno akrinatrin
Polaco akrynatryna
Sueco -
Húngaro -
Holandés -

Última actualización del registro: Saturday 02 November 2019
Contacto: aeru@herts.ac.uk