Seleccione la Opción
Inicio
A a Z Indice
Búsqueda
Términos y Condiciones
Información de Asistencia
Compras y Servicios
GET ADDITIONAL DATA HERE!

ciproconazol (Ref: SAN 619)
** cyproconazole ** CGA 221949 ** SAN 751 ** A-9898A ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

Cyproconazole is a commonly used fungicide approved for use in the EU and in many other countries. It is moderately soluble in water and readily soluble in many organic solvents. It is a volatile substance. Based on its physico-chemical properties, cyproconazole has a high risk of leaching to groundwater. It can be persistent in both soil and water systems. It is moderately toxic to mammals. It is highly toxic to birds and moderately toxic to most aquatic organisms, earthworms and honeybees.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for cyproconazole

Descripción: A broad spectrum fungicide for cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases

Ejemplos de plagas controladas: Spetoria; Net blotch; Brown rust; Yellow rust; Eyespot; Powdery mildews; Chocolate spot; Ear disease; Glume blotch

Ejemplos de aplicaciones: Cereals including wheat, barley, oats, rye; Vegetables including peas & beans, asparagus; Oilseed rape; Sugarbeet; Fruit including apples, peach; Almonds

Eficacia y actividad: Wheat/Eyespot=Low; Wheat/Mildew=Low; Wheat/Septoria=Low; Wheat/Rust=Moderate-High; Barley/Mildew=Low; Barley/Rust=Moderate; Soybean/Brown spot=High; Soybean/Leaf blight=Moderate; Soybean/Rust=High

Availability status: Current

Introduction & key dates: 1986, first reported; 1989, first introduced France & Switzerland

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur Ireland
Date inclusion expires 31/05/2021
UE Candidatas a sustitución Yes - two 'Persistent-Bioaccumulative-Toxic' criteria
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism A chiral molecule that is an approximately equal mixture of the two diastereomers, each of which is exactly a 1:1 mixture of the enantiomers.
Fórmula química C15H18ClN3O
Canonical SMILES CC(C1CC1)C(CN2C=NC=N2)(C3=CC=C(C=C3)Cl)O
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) UFNOUKDBUJZYDE-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3
¿Diagrama de estructura 2D / imagen disponible?

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Nombre Común Relación Vínculo
Cyproconazole Unstated isomer Click here for the CCDC structure diagram

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Fungicide
Grupo químico Triazole
Minimum active substance purity 940 g/kg
Known relevant impurities EU dossier - may contain diastereomers of cyproconazole
Sustancias de origen Sintéticas
Modo de acción Systemic with protective, curative and eradicant action. Disrupts membrane function. An ergosterol-biosynthesis inhibitor.
CAS RN 94361-06-5
CEE número -
Número CIPAC 600
EPA américaine chimiques de code 128993
PubChem CID 86132
Masa molecular (g mol-1) 291.78
PIN (Preferred Identification Name) mixture of the 2 enantiomeric pairs rac-(2R,3R)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol and rac-(2R,3S)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol in the ratio 1:1
Nombre IUPAC (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Nombre CAS α-(4-chlorophenyl)-α-(1-cyclopropylethyl)-1H-1,2,4-triazole-1-ethanol
Otra información de estado -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) No aplicable
Fungicide Resistance Classification (FRAC) 3
Examples of recorded resistance -
Estado físico Fine white powder
Related substances & organisms

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Dow AgroSciences
  • Syngenta
Example products using this active
  • Alto Elite
  • Cabaret
  • Caddy 240EC
  • Cherokee
  • Excelsior
  • Menara
  • Priori Xtra
  • Quadris Xtra
Estado de UK LERAP None
Formulation and application details Often supplied as soluble concentrates that are mixed with water and applied as a spray.


DESTINO AMBIENTAL

for cyproconazole

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 93 A5 Moderado
Solubilidad - en solventes organicos en 20oC (mg l-1) 360000 A5 - Acetona -
240000 A5 - Acetato de etilo -
1300 A5 - Hexano -
410000 A5 - Metanol -
Punto de fusión (oC) 106.5 A5 -
Punto de ebullición (oC) Decomposes before boiling A5 -
El punto de degradación (oC) 299 A5 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 1.23 X 1003 Calculado -
Log P 3.09 A5 Alto
Masa densidad (g ml-1)/Peso específico 1.26 L3 -
Disociación constante (pKa) at 25oC No aplicable A5 -
Nota: Ninguna disociación
Presión de vapor en 20oC (mPa) 0.026 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 5.00 X 10-05 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 3.10 Calculado Alta posibilidad de la lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 3.78 X 10-01 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Mediano
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 297nm = 0.7; [Acidic solution: 295nm = 0.4; [Basic solution: 295nm = 0.8 A5 -
Surface tension (mN m-1) 65.2 A5 -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 142 A5 Persistente
DT50 (laboratorio en 20oC) 142 A5 Persistente
DT50 (campo) 129 A5 Persistente
DT90 (laboratorio en 20oC) 422 A5 -
DT90 (campo) 579 A5 -
Endpoint de modelado DT50 - - -
Nota EU dossier lab studies DT50 range 44.9-191 days, DT90 range 149-1000 days, field studies DT50 range 62.1-501.2 days, DT90 range 179->1000 days; Other data: DT50 144 days (DW4)
Dissipation rate RL50 on plant matrix Valor 13.9 R3 -
Nota Tomato fruit, undercover, n=1
Dissipation rate RL50 on and in plant matrix Valor 11.5 R4 -
Nota Published literature RL50 range 3.5-16.0 days, 5 field crops, various matrices, n=5
Acuoso fotólisis DT50 (días) en pH 7 Valor 40 K4 Estable
Nota -
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor Estable A5 -
Nota Stable pH 4 to pH 9, 50 degC
Aqua-Sedimento DT50 (días) 1000 A5 Estable
Fase de agua sola DT50 (días) - - -

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - - -
Koc -
Notas y rango -
Freundlich Kf 8.7 A5 Móvil moderado
Kfoc 364
1/n 0.862
Notas y rango EU dossier kf range 4.1-17.0, Kfoc range 173-711 mL/g, 1/n range 0.84-0.90, Soils=5
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
1,2,4-triazole (Ref: CGA 71019) This metabolite may cause environmental pollution, click here for further information Suelo   0.170   Major fraction, Not relevant
1H-1,2,4-triazol-1-ylacetic acid (Ref: CGA 142856) Suelo   0.067   Micor fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
- triazole pyruvic acid Soil - -
- triazole lactic acid Soil - -
2-amino-3-[1,2,4] triazol-1-yl-propionic acid
(Ref: CGA 131013)
triazole alanine; TA Soil - -
(Ref: NOA 142856) triazole acetic acid Soil 0.07 -
5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid
(Ref: NOA 405870)
M21/21a Rat - -
5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid
(Ref: NOA 405872)
M36(Z2) Rat - -
(Ref: NOA 421152) - Rat (Faeces) - -
1-[(E)-2-(4-chloro-phenyl)-3-cyclopropyl-but-1-enyl]-1H-[1,2,4]triazole
(Ref: NOA 421155)
M38(Z1) - - -
1H-1,2,4-triazol-3-ol
(Ref: NOA 457654)
hydroxy triazole Soil (Aerobic) - -


ECOTOXICOLOGÍA

for cyproconazole

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 28 A5 Whole fish Bajo potencial
CT50 (días) 1 -
Mamíferos - Agudos oral LD50 (mg kg-1) < 350 A5 Rata Moderado
Mamíferos - a corto plazo NOEL (mg kg-1) 1.84 A5 Ratones Alto
(ppm dieta) 15 -
Pájaros/aves - Agudos LD50 (mg kg-1) 94 A5 Colinus virginianus Alto
Birds - Short term dietary (LC50/LD50) > 146 mg kg-1 A5 Anas platyrhynchos -
Pez - agudo 96 hora LC50 (mg l-1) 19.0 A5 Oncorhynchus mykiss Moderado
Pez - Crónico 21 días NOEC (mg l-1) 0.65 A5 Oncorhynchus mykiss Moderado
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) > 22 A5 Daphnia magna Moderado
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.29 A5 Daphnia magna Moderado
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) 8.3 F3 Americamysis bahia Moderado
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) 50.0 A4 Chironomus riparius Moderado
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) 0.059 A5 Lemna gibba Moderado
Non-target plants > 400 A5 Beta vulgaris
Vegetative vigour, ER50
as g/ha
-
> 400 A5 Beta vulgaris
Seedling emeregnce, ER50
as g/ha
-
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 0.099 A5 Scenedemus subspicatus Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) 0.02 Q2 Unknown species Moderado
Abejas mielíferas (Apis spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) > 100 A5 Bajo
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) > 100 A5 Bajo
Modo desconocido aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Abejorros (Bombus spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Abejas albañiles (Osmia spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Otros polinizadores (1) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Otros polinizadores (2) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Lombrices - Agudos 14 día LC50 (mg kg-1) 168 A5 Eisenia foetida, corr Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) 0.75 A4 Eisenia foetida, corr, formulación Moderado
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad 55.8 A4 Folsomia candida, 28 día NOEC -
Otro arthropoda (1) LR50 g ha-1 80 48 hora
A5 Aphidius rhopalosiphi, adult
-
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 35.6 7 día
A5 Typhlodromus pyri
-
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 2.5 mg kg-1 soil, 35 días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for cyproconazole

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) < 350 A5 Rata Moderado
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.47 A5 Rat (nose only) -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.02 A4 SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.02 A4 SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.02 A4 SF=100 -
Estudios den la absorción cutánea (%) 1-10 A5 concentration dependent -
Directivo 76/464 Sustancias Peligrosas - - -
Limites de exposiciones - - -
Exposure Routes Public Main route of exposure of bystanders is by spray drify but risk is considered low
Occupational No unacceptable risks to operators or other workers identified
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

Cuestiones generales de la salud humana Possible liver toxicant
Endocrine issues - Inhibition of aromatase activity, decrease of estrogens production

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H302, H361d
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Carcinogen category 3: R40
Reproduction risk category 3: R63
Xn - Harmful: R22
N - Dangerous for the environment: R50, R53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S2, S36/37, S60, S61
Clasificación de OSM II - Peligroso mediano
US EPA Classification (formulation) III - Caution - Slightly toxic
Número de las NU Usually 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRADUCCIONES

for cyproconazole

Idioma Nombre
Inglés cyproconazole
Francés cyproconazole
Alemán Cyproconazol
Danés cyproconazol
Italiano ciproconazolo
Español ciproconazol
Griego cyproconazole
Esloveno ciprokonazol
Polaco cyprokonazol
Sueco -
Húngaro cyproconazole
Holandés cyproconazool

Última actualización del registro: Tuesday 30 October 2018
Contacto: aeru@herts.ac.uk