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dicofol (Ref: ENT 23648)
** dicofol ** kelthane ** FW-293 ** decofol ** DTMC ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

Dicofol is an organochloride acaricide that is not approved for use in the EU. It has a low aqueous solubility, volatile and, based on its chemical properties, is unlikely to leach to groundwater. It is moderately persistent in soils but does not normally persist in water. It is moderately toxic to mammals and has a high tendency to bioaccumulate. Dicofol is also an irritant and neurotoxin. It has a moderate toxicity to most biodiversity including honeybees and earthworms.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for dicofol

Descripción: An acaricide used to control many species of phytophagous mite on a range of food and ornamental crops

Ejemplos de plagas controladas: Various mites including Pacific mite; two-spotted spider mite, tropical mites, tomato russet mite, citrus mite, European red mite

Ejemplos de aplicaciones: Vegetables including beans, squash, peppers; Cotton; Cucumbers; Hops; Fruit including apples, pears, citrus, grapes

Eficacia y actividad: -

Availability status: Current

Introduction & key dates: 1956, first reported; 1957, first marketed USA

CEE Regulación 1107/2009 ( 91/414):
Estado Not approved
Dossier rapporteur/co-rapporteur Spain
Date inclusion expires Expired
UE Candidatas a sustitución No aplicable
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, Estados Unidos, India

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism Isomeric - the o,p'-substituted isomer is chiral and may have enantiomer-specific activity but, the stereospecific activity of o,p'-dicofol has not been reported.
Fórmula química C14H9Cl5O
Canonical SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)(C(Cl)(Cl)Cl)O)Cl
Isomeric SMILES Clc1ccc(cc1)C(O)(c2ccc(Cl)cc2)C(Cl)(Cl)Cl
International Chemical Identifier Key (InChIKey) UOAMTSKGCBMZTC-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H9Cl5O/c15-11-5-1-9(2-6-11)13(20,14(17,18)19)10-3-7-12(16)8-4-10/h1-8,20H
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Acaricide
Grupo químico Organochlorine
Minimum active substance purity -
Known relevant impurities -
Sustancias de origen Sintéticas
Modo de acción Non-systemic with contact action
CAS RN 115-32-2
CEE número 204-082-0
Número CIPAC 123
EPA américaine chimiques de code 10501
PubChem CID 8268
Masa molecular (g mol-1) 370.49
PIN (Preferred Identification Name) 2,2,2-trichloro-1,1-bis(4-chlorophenyl)ethan-1-ol
Nombre IUPAC 2,2,2-trichloro-1,1-bis(4-chlorophenyl)ethanol
Nombre CAS 4-chloro-α-(4-chlorophenyl)-α-(trichloromethyl)benzenemethanol
Otra información de estado POP candidate; OSPAR pfa/soc; Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 2A
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance Panonychus citri
Tetranychus arabicus
Tetranychus kanzawai
Tetranychus urticae
many others
Estado físico White crystals
Related substances & organisms

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Agan Chemical
  • Makhteshim-Agan
  • Rohm & Hass
  • Sedagri
Example products using this active
  • Carbax
  • Mitigan
  • Acarin
  • Mitex
  • kelthane
  • Hilfol
Estado de UK LERAP No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as emulsifiable concentrates and wettable powders.


DESTINO AMBIENTAL

for dicofol

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 0.8 B5 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 2600000 C4 - Cloruro de metileno -
2750000 C4 - Metanol -
1350000 C4 - Xileno -
400000 L3 - Acetona -
Punto de fusión (oC) 370.5 A5 -
Punto de ebullición (oC) 193 L3 -
El punto de degradación (oC) - - -
Punto de inflamación (oC) 193 L3 - (open cup) -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 2.00 X 1004 Calculado -
Log P 4.3 L3 Alto
Masa densidad (g ml-1)/Peso específico 1.45 L3 -
Disociación constante (pKa) at 25oC - - -
Nota:
Presión de vapor en 20oC (mPa) 0.25 B5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 2.45 X 10-02 H4 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 0.36 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 8.34 X 10-03 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Alto
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 80 L3 Persistente moderado
DT50 (laboratorio en 20oC) 45 DW4 Persistente moderado
DT50 (campo) - - -
DT90 (laboratorio en 20oC) - - -
DT90 (campo) - - -
Endpoint de modelado DT50 - - -
Nota Best available data DT50 range 40-80 days
Dissipation rate RL50 on plant matrix Valor 3.7 R4 -
Nota Published literature RL50 range 1.7-5.9 days, 5 field & undercover grown crops, various matrices, n=6
Dissipation rate RL50 on and in plant matrix Valor 2.7 R4 -
Nota Published literature RL50 range 2.6-2.8 days, 36 field crops, various matrices, n=3
Acuoso fotólisis DT50 (días) en pH 7 Valor 26 K3 Lento
Nota -
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor 3.3 K3 No persistente
Nota pH sensitive: DT50 85 days at pH 5, 26 minutes at pH 9 (L3)
Aqua-Sedimento DT50 (días) 29 K2 Rápido
Fase de agua sola DT50 (días) - - -

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - H3 No Móvil
Koc 6064
Notas y rango Other source: 6945 mL/g sandy soil (H3); 5000 (G3)
Freundlich Kf - - -
Kfoc -
1/n -
Notas y rango -
pH senbsibilidad -

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
2-chlorobenzoic acid (Ref: AE-C500233) Suelo   -   -

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
1-(2-chlorophenyl)-1-(4'-chlorophenyl)-2,2-dichloroethanol - Soil (Aerobic) - -
o,p-dichlorobenzohydrol o,p-DCBH Soil (Aerobic) - -
3-hydroxy-2,4-dichlorobenzophenone OH-DCBP Soil (Aerobic) - -
2,4-dichlorobenzophenone - Soil (Photolysis) - -
2,4-dichlorobenzhydrol - Soil (Aerobic) - -
3-hydroxy-4,4'-dichlorobenzophenone 3-OH-DCBP Soil (Aerobic) - -
1,1-bis(4-chlorophenyl)-2,2-dichloroethanole - Soil (Anaerobic) - -
1-(2-chlorophenyl)-1-(4'-chlorophenyl)-2,2-dichloroethanol
(Ref: FW-152)
- Soil (Aerobic) - -


ECOTOXICOLOGÍA

for dicofol

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 10000 F4 Whole fish Alto potencial
CT50 (días) No disponible -
Mamíferos - Agudos oral LD50 (mg kg-1) 578 L3 Rata Moderado
Mamíferos - a corto plazo NOEL (mg kg-1) 0.25 L2 Rata, 2 año Alto
(ppm dieta) 5 -
Pájaros/aves - Agudos LD50 (mg kg-1) 1418 L3 Coturnix japonica Moderado
Birds - Short term dietary (LC50/LD50) - - -
Pez - agudo 96 hora LC50 (mg l-1) 0.51 L3 Lepomis macrochirus Moderado
Pez - Crónico 21 días NOEC (mg l-1) 0.0044 L3 Trucha Alto
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 0.14 L3 Daphnia magna Moderado
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 125 Q2 Daphnia magna Bajo
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 0.075 L3 Scenedemus subspicatus Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) 0.05 Q2 Unknown species Moderado
Abejas mielíferas (Apis spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) > 50 L3 Moderado
Modo desconocido aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Abejorros (Bombus spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Abejas albañiles (Osmia spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Otros polinizadores (1) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Otros polinizadores (2) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Lombrices - Agudos 14 día LC50 (mg kg-1) 43.1 L3 Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 - - -
% Causalidad Moderado dañoso Q2 Parasitoids -
Otro arthropoda (2) LR50 g ha-1 - - -
% Causalidad Nocivo Q2 Predatory mites -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for dicofol

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) 578 L3 Rata Moderado
Mammals - Dermal LD50 (mg kg-1 body weight) > 2500 L3 Rabbit -
Mammals - Inhalation LC50 (mg l-1) 5.0 L3 Rat -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.002 UK ACP 1993 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) - - -
Estudios den la absorción cutánea (%) - - -
Directivo 76/464 Sustancias Peligrosas List I; List II - -
Limites de exposiciones - - -
Exposure Routes Public Low risk to Europeans as no longer approved for use
Occupational Low risk to Europeans as no longer approved for use
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

Cuestiones generales de la salud humana Harmful by inhalation, ingestion and through skin contact
IARC group 3 carcinogen; USEPA - possible human carcinogen
Endocrine issues - Inhibition of androgen synthesis

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes No information available
CLP classification 2013 Health: H302, H312, H315, H317
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Xn - Harmful: R21/22, R43
Xi - Irritant: R38
N - Dangerous for the environment: R50, R53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S2, S36/37, S60, S61
Clasificación de OSM II - Peligroso mediano
US EPA Classification (formulation) II, III - Warning - Moderately toxic, Caution - Slightly toxic
Número de las NU -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRADUCCIONES

for dicofol

Idioma Nombre
Inglés dicofol
Francés dicofol
Alemán Dicofol
Danés dicofol
Italiano dicofol
Español dicofol
Griego dicofol
Esloveno dikofol
Polaco dikofol
Sueco -
Húngaro -
Holandés dicofol

Última actualización del registro: Tuesday 22 May 2018
Contacto: aeru@herts.ac.uk