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diflubenzuron (Ref: OMS 1804)
** diflubenzuron ** DFB ** difluron ** ENT 29054 ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

Diflubenzuron is a urea-derived insecticide that is approved for use in the EU. It has a low aqueous solubility and is volatile. Based on its chemical properties, it is not expected to leach to groundwater. It is not persistent in soils but can be in water in some circumstances. It has a low mammalian toxicity. It is moderately toxic to fish, honeybees and earthworms but more toxic to aquatic invertebrates. Diflubenzuron is relatively non-toxic to birds and algae

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for diflubenzuron

Descripción: A persistent urea derivative insecticide used to control a wide range of leaf-eating insects

Ejemplos de plagas controladas: Scararid flies; Armyworms; Leafminers, Whiteflies; Termites; Fungus gnats; Shore flies

Ejemplos de aplicaciones: Ornamentals in greenhouses, shadehouses and commercial structures; Building protection from termite colonies; Fruit

Eficacia y actividad: Efficiacy has been shown via extensive use.

Availability status: Current

Introduction & key dates: 1972, first reported; 1975, first introduced

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur Greece/Slovakia
Date inclusion expires 31/12/2019
UE Candidatas a sustitución No
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, Estados Unidos

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism -
Fórmula química C14H9ClF2N2O2
Canonical SMILES C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC=C(C=C2)Cl)F
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) QQQYTWIFVNKMRW-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Insecticide
Grupo químico Benzoylurea
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier: 4-chloroaniline
Sustancias de origen Sintéticas
Modo de acción Selective, non-systemic with contact and stomach action, acts by inhibiting chitin synthesis
CAS RN 35367-38-5
CEE número 252-529-3
Número CIPAC 339
EPA américaine chimiques de code 108201
PubChem CID 37123
Masa molecular (g mol-1) 310.68
PIN (Preferred Identification Name) N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide
Nombre IUPAC 1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl)urea
Nombre CAS N-(((4-chlorophenyl)amino)carbonyl)-2,6-difluorobenzamide
Otra información de estado -
Relevant Environmental Water Quality Standards UK Environment Agency non-statutory standard for the protection of aquatic life in freshwater annual average 0.001 ug/L, max acceptable conc 0.015 ug/L
UK Environment Agency non-statutory standard for the protection of aquatic life in saltwater annual average 0.005 ug/L, max acceptable conc 0.01 ug/L
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 15
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance Cydia pomonella
Plutella xylostella
Spodoptera littoralis
Lucilia cuprina
Spodoptera exigua
Estado físico White crystalline solid
Related substances & organisms -

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Certis
  • Chemtura
  • Duphar
Example products using this active
  • Dimilin Flo
  • Dimilin WG-80
  • Astonex
Estado de UK LERAP Buffer probably required in UK - see product label
Formulation and application details Supplied in a variety of formulations including wettable powders, oil-dispersable concentrates and granules.


DESTINO AMBIENTAL

for diflubenzuron

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 0.08 A5 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 6980 A5 - Acetona -
63 A5 - n-Hexano -
290 A5 - Tolueno -
1100 A5 - Metanol -
Punto de fusión (oC) 227.6 A5 -
Punto de ebullición (oC) Decomposes before boiling at normal pressure A5 -
El punto de degradación (oC) - - -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 7.76 X 1003 Calculado -
Log P 3.89 A5 Alto
Masa densidad (g ml-1)/Peso específico 1.57 A5 -
Disociación constante (pKa) at 25oC - - -
Nota:
Presión de vapor en 20oC (mPa) 0.00012 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 4.70 X 10-04 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 0.17 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 1.26 X 10-03 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Mediano
Maximum UV-vis absorption L mol-1 cm-1 In acetonitrile 257nm = 15148, 290nm = 10500 A5 -
Surface tension (mN m-1) - - -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 3 K4 No persistente
DT50 (laboratorio en 20oC) 3.2 A5 No persistente
DT50 (campo) - - -
DT90 (laboratorio en 20oC) - - -
DT90 (campo) - - -
Endpoint de modelado DT50 - - -
Nota EU dossier lab studies DT50 range 2.0-6.7 days
Dissipation rate RL50 on plant matrix Valor 14.2 R4 -
Nota Published literature RL50 range 7.9-23.7 days, 2 field crops, various matrices, n=3
Dissipation rate RL50 on and in plant matrix Valor 11.7 R4 -
Nota Published literature RL50 range 2.8-21.0 days, 4 field & undercover grown crops, various matrices, n=4
Acuoso fotólisis DT50 (días) en pH 7 Valor 80 A5 Estable
Nota Not a significant degradation route
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor 96 K4 Persistente moderado
Nota Stable pH 5 to pH 7, some hydrolysis at pH 9
Aqua-Sedimento DT50 (días) 4.5 A5 Rápido
Fase de agua sola DT50 (días) 3.0 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - - -
Koc -
Notas y rango -
Freundlich Kf 65.2 A5 No Móvil
Kfoc 4620
1/n 1.1
Notas y rango EU dossier Kf range 34.2-97.7 mL/g, Kfoc range 1983-6918 mL/g, 1/n range 0.97-1.22, Soils=4
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
4-chlorophenylurea This metabolite may cause environmental pollution, click here for further information Suelo   0.308   Major fraction, Relevant
2,6-difluorobenzoic acid This metabolite may cause environmental pollution, click here for further information Suelo   0.133   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
4-chloroaniline
Nota: Mutagenic
PCA Plant; Animal - -
4-chloroacetanilide PCAA Animal - -
2,6-difluorobenzamide DFBAM Rat; Animal (Milk) - -


ECOTOXICOLOGÍA

for diflubenzuron

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 320 A5 (Other literature Log BCF range 2.9-3.6 (R3)) Umbral de importancia
CT50 (días) 0.6 -
Mamíferos - Agudos oral LD50 (mg kg-1) > 4640 A5 Rata Bajo
Mamíferos - a corto plazo NOEL (mg kg-1) - - -
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) > 5000 A5 Colinus virginianus Bajo
Birds - Short term dietary (LC50/LD50) > 1206 mg kg-1 bw/día A5 Colinus virginianus -
Pez - agudo 96 hora LC50 (mg l-1) > 0.13 A5 Oncorhynchus mykiss Moderado
Pez - Crónico 21 días NOEC (mg l-1) 0.2 A5 Oncorhynchus mykiss Moderado
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 0.0026 A5 Daphnia magna Alto
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.00004 A5 Daphnia magna Alto
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) 0.0021 F3 Americamysis bahia Alto
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) > 0.19 A5 Lemna gibba Moderado
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 20 A5 Pseudokirchneriella subcapitata Bajo
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) 1 Q2 Unknown species Moderado
Abejas mielíferas Contacto aguda 48 hora LD50 (μg abeja-1) > 74.2 A5 Apis mellifera Moderado
Oral aguda 48 hora LD50 (μg abeja-1) > 9.1 A5 Apis mellifera Moderado
Modo desconocido aguda 48 hora LD50 (μg abeja-1) - - -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 500 A5 Eisenia foetida, corr Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) 500 A5 Eisenia foetida, 56 día corr Bajo
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 - - -
% Causalidad Inofensivo Dose: 300 g ha-1
AA3 Typhlodromus pyri
-
Otro arthropoda (2) LR50 g ha-1 - - -
% Causalidad Nocivo Dose: 300 g ha-1
AA3 Chrysoperla carnea
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 0.75 kg ha-1
-
Mesocosm study data NOEAEC mg l-1 0.00007 A5 Zooplankton EAC -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for diflubenzuron

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) > 4640 A5 Rata Bajo
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rabbit -
Mammals - Inhalation LC50 (mg l-1) > 2.5 A5 Rat, 4 hr (nose only, dust) -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.1 A5 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) Ningunos asignaron A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.033 A5 Dog, SF=100 -
Estudios den la absorción cutánea (%) 0.2-13 A5 concentration dependant -
Directivo 76/464 Sustancias Peligrosas - - -
Limites de exposiciones - - -
Exposure Routes Public No unacceptable risks identified
Occupational Acceptable risks for proposed uses - PPE/PPC advised
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 Calc MAC=60 μg l-1 -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

Cuestiones generales de la salud humana Reported to cause methaemoglobinaemia
Endocrine issues - Pregnane X cellular receptor activation
Possible liver & spleen toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H373
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Xi - Irritant: R36
N - Dangerous for the environment: R50/53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S2, S13, S20/21, S26, S39, S60/61
Clasificación de OSM III - Peligroso un poco
US EPA Classification (formulation) III - Caution - Slightly toxic
Número de las NU Usually 3077 or 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRADUCCIONES

for diflubenzuron

Idioma Nombre
Inglés diflubenzuron
Francés diflubenzuron
Alemán Diflubenzuron
Danés diflubenzuron
Italiano diflubenzuron
Español diflubenzuron
Griego -
Esloveno diflubenuron
Polaco diflubenzuron
Sueco diflubensuron
Húngaro diflubenzuron
Holandés diflubenzuron

Última actualización del registro: Tuesday 14 May 2019
Contacto: aeru@herts.ac.uk