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metaflumizon (Ref: BAS 320l)
** metaflumizone ** NNI 0250 ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio
Otros datos se pueden encontrar en el VSDB

RESUMEN

Metaflumizone is a semicarbazone broad-spectrum insecticide. It has a low aqueous solubility, is non-volatile and a low potential for leaching to groundwater based on its chemical properties. It is persistent in soil and in water-sediment systems. It has a low mammalian toxicity and considered to have potential negative reproduction/developmental effects. It also has a high potential for bioaccumulation. It has a low to moderate toxicity to most birds, aquatic species, honeybees and earthworms.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for metaflumizone

Descripción: An insecticide active against key insect pests including. Also has some veterinary applications.

Ejemplos de plagas controladas: Lepidoptera; Coleoptera; Hymenoptera; Isoptera; Diptera

Ejemplos de aplicaciones: Cotton; Potatoes; Greenhouse tomatoes & peppers;

Eficacia y actividad: -

Availability status: Current

Introduction & key dates: 2008, developed

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires 31/12/2024
UE Candidatas a sustitución No
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Estados Unidos

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism Optical isomeric mixture in the ratio E:Z of 90:10
Fórmula química C24H16F6N4O2
Canonical SMILES C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N
Isomeric SMILES C1=CC(=CC(=C1)C(F)(F)F)/C(=N\NC(=O)NC2=CC=C(C=C2)OC(F)(F)F)/CC3=CC=C(C=C3)C#N
International Chemical Identifier Key (InChIKey) MIFOMMKAVSCNKQ-QNKGDIEWSA-N
International Chemical Identifier (InChI) InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/f/h32,34H
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Insecticide, Veterinary substance
Grupo químico Semicarbazone
Minimum active substance purity 945 g/kg
Known relevant impurities EU dossier - hydrazine <1mg/kg; toluene <2mg/kg; 4-(trifluoromethoxy)phenyl isocyanate < 100mg/kg
Sustancias de origen Sintéticas
Modo de acción Broad-spectrum, attacks insect nervous system causing paralysis
CAS RN 139968-49-3
CEE número -
Número CIPAC 779
EPA américaine chimiques de code 281250
PubChem CID 20056430
Masa molecular (g mol-1) 506.40
PIN (Preferred Identification Name) -
Nombre IUPAC (EZ)-2'-[2-(4-cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-4-(trifluoromethoxy)carbanilohydrazide
Nombre CAS 2-(2-(4-cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)-N-(4-(trifluoromethoxy)phenyl)hydrazinecarboxamide
Otra información de estado PAN listed Highly Hazardous Chemical
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 22B
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance -
Estado físico White powder
Related substances & organisms

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • BASF
Example products using this active
  • ProMeris
  • Alverde
  • Siesta
Estado de UK LERAP No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as a bait formulation or as spot-on solutions.


DESTINO AMBIENTAL

for metaflumizone

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 0.0018 R4 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 85 A5 - n-Hexano -
4000 A5 - Tolueno -
153300 A5 - Acetona -
14100 A5 - Metanol -
Punto de fusión (oC) 133 A4 - Específico del isómero -
Punto de ebullición (oC) Decomposes before boiling A5 -
El punto de degradación (oC) 232 A5 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 3.98 X 1004 Calculado -
Log P 4.6 A5 - mean of isomers Alto
Masa densidad (g ml-1)/Peso específico 1.46 R4 -
Disociación constante (pKa) at 25oC n/a A5 -
Nota: Ninguna disociación
Presión de vapor en 20oC (mPa) 2.32 X 10-08 A5 - mean of isomers Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 0.11 A5 - Z-isomer Volátil moderado
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index -1.05 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 5.35 X 10-03 Calculado -
Nota Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Alto
Maximum UV-vis absorption L mol-1 cm-1 Max @ 234nm=38100, 280nm=19300 A5 -
Surface tension (mN m-1) 70.5 A5 0.01% solution -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 141 A5 Persistente
DT50 (laboratorio en 20oC) 141 A5 Persistente
DT50 (campo) 13.8 A5 No persistente
DT90 (laboratorio en 20oC) 362 A5 -
DT90 (campo) 67.8 A5 -
Endpoint de modelado DT50 - - -
Nota EU dossier lab studies DT50 range 65-376 days, DT90 range 153-728 days, Field studies DT50 range 3.9-53.3 days, DT90 range 9.9-114 days; Manufacturers published data DT50 range 4.3-27 days
Dissipation rate RL50 on plant matrix Valor 1.9 R3 -
Nota cabbage leaves, n=1
Dissipation rate RL50 on and in plant matrix Valor 4.5 R3 -
Nota Rice straw, n=1
Acuoso fotólisis DT50 (días) en pH 7 Valor 3.28 A4 Moderado rápido
Nota EU dossier states DT50 2.43-4.12 days
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor ND A3 -
Nota EU dossier States DT50 5-6 days @ pH 4
Aqua-Sedimento DT50 (días) 451 A5 Estable
Fase de agua sola DT50 (días) 1.0 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd 529 A5 No Móvil
Koc 30714
Notas y rango EU dossier Kd range 299-1030 mL/g, Koc range 16500-51000 mL/g
Freundlich Kf - - -
Kfoc -
1/n -
Notas y rango -
pH senbsibilidad -

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
4-(5-hydroxy-3-oxo-4(4-(trifluoromethoxy)phenyl)-6-(3-trifluoromethyl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-5-yl)benzonitrile (Ref: M320I23) Suelo   0.081   Minor fraction, Relevant
benzonitrile carboxylic acid (Ref: M320I06) Suelo   0.084   Minor fraction, Relevant
m-trifluoromethyl benzoic acid (Ref: M320I29) This metabolite may cause environmental pollution, click here for further information Suelo   0.211   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
- M320I19 Rat - -
- M320I20 Rat - -
- M320I21 Rat - -
- M320I22 Animal - -
- M320I24 Animal - -
- M320I25 Animal; Hen - -
- M320I26 Animal; Hen - -
- M320I27 Hen - -
- M320I18 Rat - -
(Ref: CL1023720) M320I10 Rat; Animal - -
(Ref: CL1023721) M320I11 Rat - -
(Ref: CL1023722) M320I12 Rat - -
(Ref: CL1023723) M320I14 Rat - -
(Ref: CL1023724) M320I15 Rat - -
(Ref: CL1023725) M320I16 Rat - -
(Ref: CL1023726) M320I17 Rat; Animal - -
(Ref: CL1500789) M320I07 Rat; Animal; Plant; Soil - -
(Ref: CL269463) M320I13 Rat; Animal - -
2-(2-oxo-2-(3-trifluoromethyl)phenyl)ethyl)-benzonitrile
(Ref: CL397864)
Nota: Cas no: 146653-56-7
M320I04 Rat; Animal; Plant; Soil; Water; Sediment - -
(Ref: CL397865) M320I09 Soil; Water; Sediment - -
trifluoro-methoxy aniline
(Ref: CL65504)
M320I05 Rat; Plant; Soil; Water; Sediment - -
(Ref: CL952480) M320I08 Soil; Water; Sediment - -


ECOTOXICOLOGÍA

for metaflumizone

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 7800 A5 Lepomis macrochirus Alto potencial
CT50 (días) 14 -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A5 Rata Bajo
Mamíferos - a corto plazo NOEL (mg kg-1) - - -
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) > 2025 A5 Colinus virginianus Bajo
Birds - Short term dietary (LC50/LD50) - - -
Pez - agudo 96 hora LC50 (mg l-1) > 0.228 A5 Oncorhynchus mykiss Moderado
Pez - Crónico 21 días NOEC (mg l-1) - - -
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) > 0.331 A5 Daphnia magna Moderado
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 1.47 A5 Daphnia magna Moderado
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) > 289 A5 Americamysis bahia Bajo
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) 1.8 A5 Chironomus riparius Moderado
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 0.0256 A5 Chironomus riparius Moderado
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) > 0.311 A5 Pseudokirchneriella subcapitata Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) - - -
Abejas mielíferas Contacto aguda 48 hora LD50 (μg abeja-1) 1.65 A5 Moderado
Oral aguda 48 hora LD50 (μg abeja-1) 2.43 A5 Moderado
Modo desconocido aguda 48 hora LD50 (μg abeja-1) - - -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 500 A5 , corr Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 3.25 >, as L product ha-1 (BAS 320 00 I: Conc 240 g l-1)
A5 Typhlodromus pyri
-
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 0.0145 as L product ha-1 (BAS 320 00 I: Conc 240 g l-1)
A5 Aphidius rhopalosiphi
-
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 0.2 mg kg-1 soil, 28 días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for metaflumizone

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A5 Rata Bajo
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.2 A5 Rat -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.03 A5 Dog, SF=100x2 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.13 A5 Rat, SF=100x3 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.01 A5 Dog, SF=100x17% -
Estudios den la absorción cutánea (%) 0.2-0.4 A5 concentration dependent -
Directivo 76/464 Sustancias Peligrosas Lista II - -
Limites de exposiciones - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

Cuestiones generales de la salud humana Liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 None allocated at this time
CEE clasificación de riesgos Click here to view information omn the EU risk phrases Xn - Harmful: R48/22
Xi - Irritant: R36
N - Dangerous for the environment: R50/53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S35, S57, S60, S61
Clasificación de OSM NL - No inscripto en la lista
US EPA Classification (formulation) No consensus across products or no products available - -
Número de las NU 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRADUCCIONES

for metaflumizone

Idioma Nombre
Inglés metaflumizone
Francés metaflumizone
Alemán Metaflumizon
Danés metaflumizon
Italiano metaflumizone
Español metaflumizon
Griego -
Esloveno metaflumizon
Polaco metaflumizon
Sueco -
Húngaro -
Holandés -

Última actualización del registro: Thursday 23 August 2018
Contacto: aeru@herts.ac.uk