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metiocarb (Ref: OMS 93)
** methiocarb ** mercaptodimethur ** ENT 25726 ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

Methiocarb is a carbamate pesticide currently approved for use in the EU. It has a low aqueous solubility, low volatility and, based on its chemical properties, it would not normally be expected to leach to groundwater. However, it has been detected in several countries. It is not normally persistent in soil or water systems. It is highly toxic to mammals, a cholinesterase inhibitor and a neurotoxin. It is also highly toxic to most fauna and flora including honey bees. The main exception is earthworms where the toxicity appears to be low.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for methiocarb

Descripción: A molluscicide and insecticide for control of a variety of plant pests. It also has application as a pheasant repellent.

Ejemplos de plagas controladas: Slugs and snails; Birds; Fruit flies; Mites; Leafhoppers; Aphids; Psylla, Meallybugs; Scale insects; Thrips; Some soil pests

Ejemplos de aplicaciones: Most agricultural crops including maize, oilseed rape, pulses, root & tuber crops, lettuce; Fruit including cherries, blueberries, peaches

Eficacia y actividad: Efficiacy is supported by long-term use across Europe and experimental work in various EU countries.

Availability status: Current

Introduction & key dates: 1962 first introduced; first registered as a pesticide in the US in 1972

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur UK/Germany
Date inclusion expires 31/07/2019
UE Candidatas a sustitución No
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, Estados Unidos

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism None
Fórmula química C11H15NO2S
Canonical SMILES CC1=CC(=CC(=C1SC)C)OC(=O)NC
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) YFBPRJGDJKVWAH-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Insecticide, Molluscicide, Bird repellent
Grupo químico Carbamate
Minimum active substance purity 980 g/kg
Known relevant impurities EU dossier - None declared
Sustancias de origen Sintéticas
Modo de acción Non-systemic with neurotoxic contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 2032-65-7
CEE número 217-991-2
Número CIPAC 165
EPA américaine chimiques de code 100501
PubChem CID 16248
Masa molecular (g mol-1) 225.31
PIN (Preferred Identification Name) -
Nombre IUPAC 4-methylthio-3,5-xylyl methylcarbamate
Nombre CAS 3,5-dimethyl-4-(methylthio)phenyl methylcarbamate
Otra información de estado Potential groundwater contaminant - previously detected in US, Australia, Mexico and Spain; Not approved for use as pelleted molluscicide in the EU.
Relevant Environmental Water Quality Standards UK Environment Agency non-statutory standard for the protection of aquatic life in freshwater and saltwater annual average 0.01 ug/L, max acceptable conc 0.16 ug/L
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 1A
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance Frankliniella occidentalis
Estado físico Colourless crystals
Related substances & organisms -

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Interfarm
  • Mobay
Example products using this active
  • Decoy
  • Draza
  • Exit Wetex
  • Huron
  • Karan
  • Rivet
  • Mesurol
Estado de UK LERAP None
Formulation and application details Often supplied for use as a seed treatment but also available as pellets or granules and applied directly to soil surface.


DESTINO AMBIENTAL

for methiocarb

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 27 A5 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 20000 A5 - Xileno -
144000 A5 - Acetona -
87000 A5 - Acetato de etilo -
31000 A5 - 1-Octanol -
Punto de fusión (oC) 118.5 A5 -
Punto de ebullición (oC) 311 A5 -
El punto de degradación (oC) 300 A5 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 1.51 X 1003 Calculado -
Log P 3.18 A5 Alto
Masa densidad (g ml-1)/Peso específico 1.25 A5 -
Disociación constante (pKa) at 25oC No aplicable A5 -
Nota: Ninguna disociación
Presión de vapor en 20oC (mPa) 1.50 X 10-02 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 1.20 X 10-04 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 0.55 Calculado Bajo posibilidad de lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 1.50 X 10-03 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Bajo
Maximum UV-vis absorption L mol-1 cm-1 pH 7: 203nm=44762, 223nm=12021, 267nm=2582
pH 2: 203nm=52548, 223nm=13026, 267nm=3030
pH 10: 219nm=23298, 267nm=11461
A5 -
Surface tension (mN m-1) 72.0 A5 at 20oC -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general Not likely to be readily biodegradable
Degradación de suelo (días) (aerobic) DT50 (típico) 2.94 A5 No persistente
DT50 (laboratorio en 20oC) 2.94 A5 No persistente
DT50 (campo) 35 B5 Persistente moderado
DT90 (laboratorio en 20oC) 12.08 A5 -
DT90 (campo) - - -
Endpoint de modelado DT50 1.4 A5 normalised geometric mean -
Nota EU 2017 dossier lab studies DT50 range 0.5-11.3 days, DT90 range 1.7-48.1 days, Soils=5; Other sources: 30 days (DW4)
Dissipation rate RL50 on plant matrix Valor 8.0 R4 -
Nota Published literature RL50 range 1.7-11.5 days, 2 field & undercover growncrops, various matrices, n=3
Dissipation rate RL50 on and in plant matrix Valor 2.4 R4 -
Nota Published literature RL50 range 2.35-2.40 days, 2 undercover grown crops, various matrices, n=2
Acuoso fotólisis DT50 (días) en pH 7 Valor 11 A5 Moderado rápido
Nota DT50 6 - 16 days for range of environmental scenarios
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor 24 A5 No persistente
Nota pH sensitive: DT50 321 days at pH 5, 0.21 days at pH 9, all at 25 degC
Aqua-Sedimento DT50 (días) 4.0 A5 Rápido
Fase de agua sola DT50 (días) 1.6 A5 Moderado rápido

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - - -
Koc -
Notas y rango -
Freundlich Kf 5.88 A5 Móvil un poco
Kfoc 660
1/n 0.832
Notas y rango EU 2017 dossier Kf range 0.43-0.9 mL/g, Kfoc range 408-1000 mL/g, 1/n range 0.81-0.87, Soils=4
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
methiocarb sulfoxide This metabolite may cause environmental pollution, click here for further information Suelo   0.588   Major fraction, Relevant
methiocarb sulfoxide phenol This metabolite may cause environmental pollution, click here for further information Suelo   0.360   Major fraction, Relevant
methiocarb sulfone phenol This metabolite may cause environmental pollution, click here for further information Suelo   0.198   Major fraction, Relevant
methiocarb methoxy sulfone This metabolite may cause environmental pollution, click here for further information Suelo   0.132   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
- methiocarb phenol; methiocab metabolite M03 Plant - -


ECOTOXICOLOGÍA

for methiocarb

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 75 A5 Lepomis macrochirus Bajo potencial
CT50 (días) 1 -
Mamíferos - Agudos oral LD50 (mg kg-1) 19 A5 Rata Alto
Mamíferos - a corto plazo NOEL (mg kg-1) 1.3 B5 Rata Alto
(ppm dieta) 10 -
Pájaros/aves - Agudos LD50 (mg kg-1) 5 A5 Coturnix japonica Alto
Birds - Short term dietary (LC50/LD50) 1071 mg kg feed-1 A5 Anas platyrhynchos -
Pez - agudo 96 hora LC50 (mg l-1) 0.65 A5 Oncorhynchus mykiss Moderado
Pez - Crónico 21 días NOEC (mg l-1) 0.05 A5 Oncorhynchus mykiss Moderado
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 0.008 A5 Daphnia magna Alto
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.0001 A5 Daphnia magna Alto
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) 2.2 A5 Scenedemus subspicatus Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) 3.2 Q2 Unknown species Bajo
Abejas mielíferas (Apis spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 0.23 A5 Apis mellifera Alto
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 0.08 A5 Apis mellifera Alto
Modo desconocido aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Abejorros (Bombus spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) 19.3 A5 Bombus terrestris Moderado
-
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
-
Abejas albañiles (Osmia spp.) Contacto aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Oral aguda LD50 (peor caso de 24 , 48 y 72 hora valores - μg abeja-1) - - -
Otros polinizadores (1) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) 0.547 A4 Apis mellifera larvae, 72hr Alto
Modo de exposición Bee brood development
Otros polinizadores (2) Agudos LD50 (peor caso de 24 , 48 y 72 hora valores - μg insect-1) - - -
Modo de exposición -
Lombrices - Agudos 14 día LC50 (mg kg-1) 1322 A5 Bajo
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) 0.32 A3 Moderado
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 0.47 48 hora
A5 Aphidius rhopalosiphi, adult
-
% Causalidad - - -
Otro arthropoda (2) LR50 g ha-1 33.7 7 día
A5 Typhlodromus pyri
-
% Causalidad - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 1.47 mg kg-1 soil, 28días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for methiocarb

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) 19 A5 Rata Alto
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 0.433 A5 Rat, 4 hr -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.013 A5 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.013 A5 Dog, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) 0.016 A5 Rat, Sf=100 -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.013 A5 Dog, SF=100 -
Estudios den la absorción cutánea (%) 1-2 A5 concentration dependent -
Directivo 76/464 Sustancias Peligrosas - - -
Exposure Routes Public Negligible risk to bystanders as pesticide used normally as a seed dressing
Occupational Negligible risk to operators
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotóxico Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A2; B3; C3; D0; E3

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

Cuestiones generales de la salud humana Endocrine issues - Inhibition of androgen activity and increase of estrogen one,
Clave: Genotoxicidad
A: Aberración cromosómica (base de datos EFSA)
B: Daño/reparación del ADN (base de datos EFSA)
C: Mutación genética (base de datos EFSA)
D: Mutación del genoma (base de datos EFSA)
E: Tipo de genotoxicidad no especificada (fuente de datos diversos)
0: Sin datos
1: Positivo
2: Resultados mixtos/ambiguos
3: Negativo
Clave: Otro
: Sí, se sabe que causa un problema
: No, sabe no causar un problema
: Posiblemente, estado no identificado
- : Datos no encontrados

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 health, H300, H301, H330
Environment: H400, H410
CEE clasificación de riesgos Click here to view information omn the EU risk phrases T - Toxic: R25
N - Dangerous for the environment: R50, R53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases S1/2, S22, S37, S45, S60, S61
Clasificación de OSM Ib - Peligroso alto
Número de las NU 2757
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRADUCCIONES

for methiocarb

Idioma Nombre
Inglés methiocarb
Francés methiocarb
Alemán Methiocarb
Danés mercaptodimethur
Italiano metiocarb
Español metiocarb
Griego mercaptodimethur
Esloveno metiokarb
Polaco metiokarb
Sueco metiokarb
Húngaro mercaptodimethur
Holandés metiocarb

Última actualización del registro: Tuesday 25 June 2019
Contacto: aeru@herts.ac.uk