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metoxifenocida (Ref: RH 2485)
** methoxyfenozide ** RH 112485 ** Traducciones

Destino ambiental - Ecotoxicología - La salud humana - A a Z Indice - Inicio

RESUMEN

An insectide approved for use in the EU and many other countries on a broad range of fruit and vegetables. It has a low aqueous solubility and a low volatility. Based on its chemical properties there is a high risk of leaching to groundwater and under some conditions it may be persistent in soil systems. It has a low oral toxicity to mammals and no significant risk issues to human health have been identified. It has a low toxicity to birds and honeybees but is relatively more toxic to aquatic species and earthworms.

INFORMACIÓN GENERAL Click here for an explantaion of the general chemical status information
for methoxyfenozide

Descripción: An insecticide used to control various insects including moths and butterflies

Ejemplos de plagas controladas: Codling moth; Lesser appleworm; Oriental fruit moth; Leafrollers; Loopers; Cotton bollworm; Armyworm; Bud moths

Ejemplos de aplicaciones: Leafy vegetables; Fresh herbs; Lettuce; Salads; Herbs; Brassicas; Cotton; Pome fruit; Grapes; Sweetcorn; Maize; Peppers; Aubergines

Eficacia y actividad: The effectiveness of methoxyfenozide for the approved uses has been deminstrated via field trials and extensive use.

Availability status: Current

Introduction & key dates: 1996, first reported; 1998, first marketed

CEE Regulación 1107/2009 ( 91/414):
Estado Approved
Dossier rapporteur/co-rapporteur UK/Slovakia
Date inclusion expires 31/07/2019
UE Candidatas a sustitución No
Incluido en la base de datos de la UE

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, Estados Unidos, Argentina, Brasil, Colombia, Israel, Japón, México, Corea

Estructura química: Click here for further information on the general chemical status information used on this site
Isomerism -
Fórmula química C22H28N2O3
Canonical SMILES CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C(=CC=C2)OC)C)C
Isomeric SMILES No data
International Chemical Identifier Key (InChIKey) QCAWEPFNJXQPAN-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)
¿Diagrama de estructura 2D / imagen disponible?

Estado general: Click here for further information on the general chemical status information used on this site
Tipo de pesticida Insecticide
Grupo químico Diacylhydrazine
Minimum active substance purity 970 g/kg
Known relevant impurities EU dossier - butylhydrazine
Sustancias de origen Sintéticas
Modo de acción A moulting accelerator that is an agonist of the hormone 20-hydroxyecdysone
CAS RN 161050-58-4
CEE número -
Número CIPAC 656
EPA américaine chimiques de code 121027
PubChem CID 105010
Masa molecular (g mol-1) 368.47
PIN (Preferred Identification Name) -
Nombre IUPAC N-tert-butyl-N'-(3-methoxy-o-toluoyl)-3,5-xylohydrazide
Nombre CAS 3-methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
Otra información de estado -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) No aplicable
Herbicide Resistance Classification (WSSA) No aplicable
Insecticide Resistance Classification (IRAC) 18A
Fungicide Resistance Classification (FRAC) No aplicable
Examples of recorded resistance Cydia pomonella
Deraeocoris brevis
Spodoptera exigua
Estado físico White powder
Related substances & organisms -

Formulaciones:
Propiedad Click here for information on the general product and branding information used on this site Valor
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Dow AgroSciences
  • Agrovista
Example products using this active
  • Intrepid
  • Runner
  • Prodigy
  • Falcon
  • Runner
  • Trotter
Estado de UK LERAP None
Formulation and application details Often supplied as a soluble concentrate that is mixed with water and used as a foliar spray.


DESTINO AMBIENTAL

for methoxyfenozide

Propiedad Click here for information on the parameters used to describe environmental fate on this site Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with fate data Interpretación Click here for information on the way in which we interpret environmental fate data
Solubilidad - En aqua en 20oC (mg l-1) 3.3 A5 Bajo
Solubilidad - en solventes organicos en 20oC (mg l-1) 115000 A5 - Metanol -
69000 A5 - Acetona -
28000 A5 - Cloruro de metileno -
600 A5 - Xileno -
Punto de fusión (oC) 185 A5 -
Punto de ebullición (oC) Decomposes before boiling A5 -
El punto de degradación (oC) 262.9 A5 -
Punto de inflamación (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-aqua coeficiente de particiónat en pH 7, 20oC P 5.25 X 1003 Calculado -
Log P 3.72 A5 Alto
Masa densidad (g ml-1)/Peso específico 0.634 A5 -
Disociación constante (pKa) at 25oC 12.20 A5 -
Nota:
Presión de vapor en 20oC (mPa) 1.33 X 10-02 A5 Baja volatilidad
Constante de Henry a 25oC (Pa m3 mol-1) 1.64 X 10-04 A5 No volátil
Indice de potencial de lixiviación GUS Click here for a note on the limitations of the GUS index 4.35 Calculado Alta posibilidad de la lixiviación
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Valor 2.21 X 10+00 Calculado -
Nota -
Potencial para transportar de 'particle bound' Click here for a note on the limitations of the potential for particle bound transport index - Calculado Mediano
Maximum UV-vis absorption L mol-1 cm-1 pH 7: 216nm=12819, 280nm=2503, 290nm=1561
pH 2: 216nm=12881, 279nm=2916, 290nm=1912
pH 10: 225nm=11312, 276nm=2937, 290nm=1548
A5 -
Surface tension (mN m-1) 58.0 A5 at 20 degC, 99.4% -

Degradación:
Propiedad Click here for information on the parameters used to describe substance degradation Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with degradation data Interpretación Click here for information on the way in which we interpret substance degradation data
Biodegradabilidad general -
Degradación de suelo (días) (aerobic) DT50 (típico) 456 A5 Persistente muy alta
DT50 (laboratorio en 20oC) 456 A5 Persistente muy alta
DT50 (campo) 68 A4 Persistente moderado
DT90 (laboratorio en 20oC) 1905 A5 -
DT90 (campo) 717 A3 -
Endpoint de modelado DT50 - - -
Nota EU 2016 dossier lab studies range DT50 81->1000 days, DT90 range 290-6340 days, Soils=14; EU 2004 dossier lab studies range 336-1100 days, DT90 range 1618 5302 days, field study range 39-133 days, DT90 range 434->1000 days; Other sources: 683 days (DW4)
Dissipation rate RL50 on plant matrix Valor - - -
Nota -
Dissipation rate RL50 on and in plant matrix Valor 5.3 R4 -
Nota Published literature RL50 range 4.3-6.2 days, 2 field & undercover grown crops, various matrices, n=2
Acuoso fotólisis DT50 (días) en pH 7 Valor Estable A5 -
Nota -
Acuoso hidrólisis DT50 (días) en 20oC y pH 7 Valor Estable C4 -
Nota Stable pH 5 to pH 9, 25 degC
Aqua-Sedimento DT50 (días) 208.6 A5 Lento
Fase de agua sola DT50 (días) - - -

De absorción del suelo y la movilidad:
Propiedad Click here for information on the parameters used to describe substance adsorption and mobility Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretación Click here for information on the way in which we interpret substance adsorption and mobility
Lineal Kd - A4 Móvil moderado
Koc 402
Notas y rango EU 2004 dossier Koc range 200-922 mL/g; Other sources: 365 mL/g (DW3)
Freundlich Kf 2.87 A5 Móvil moderado
Kfoc 231
1/n 0.936
Notas y rango EU 2016 dossier Kf range 1.53-6.2 mL/g, kfoc range 132-365 mL/g, 1/n range 0.85-1.00, Soils=16
pH senbsibilidad No

Key metabolites:
Metabolito Medio de formación Maximó Calculado de Fracción Ocurrencia 1107/2009 Importancia Click here for further information on 1107/2009 relevancy
(N-(3-methoxy-2-methylbenzoyl)-N-(3-carboxy-5-methylbenzoyl)-N-tert-butylhydrazine) (Ref: RH-131154) This metabolite may cause environmental pollution, click here for further information Suelo   0.158   Major fraction; Relevant

Other known metabolites:
Metabolite name and reference Aliases Medio de formación / Rate Maximó Calculado de Fracción Ocurrencia Metabolising enzymes
- desmethylated methoxyfenozide; methoxyfenozide metabolite M14 Animal (Urinary, Faeces); Rat; Water/sediment - -
- hydroxy methyl methoxyfenozide; methoxyfenozide metabolite M24 Animal (Urinary, Faeces) - -
3,5-dimethylbenzoic acid N-tert-butyl-N-(3-hydroxy-2-methylbenzoyl)-hydrazide RH-117236 - - -


ECOTOXICOLOGÍA

for methoxyfenozide

Propiedad Click here for information on the parameters used to describe substance ecotoxicology Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretación Click here for information on the way in which we interpret substance ecotoxicology
Factor de la bio-concentración BCF (l kg-1) 11 A5 Whole fish Bajo potencial
CT50 (días) No disponible -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A5 Rata Bajo
Mamíferos - a corto plazo NOEL (mg kg-1) > 10 L2 Rata, 2 año Alto
(ppm dieta) - -
Pájaros/aves - Agudos LD50 (mg kg-1) > 2250 A5 Colinus virginianus Bajo
Birds - Short term dietary (LC50/LD50) > 5620 mg kg feed-1 A5 Colinus virginianus -
Pez - agudo 96 hora LC50 (mg l-1) > 4.2 A5 Oncorhynchus mykiss Moderado
Pez - Crónico 21 días NOEC (mg l-1) 2.4 A5 Pimephales promelas Moderado
Invertebrados acuáticos - Agudos 48 hora EC50 (mg l-1) 3.7 A5 Daphnia magna Moderado
Invertebrados acuáticos - Crónicos 21 días NOEC (mg l-1) 0.39 A5 Daphnia magna Moderado
Crustáceos acuáticos - Agudos 96 hora LC50 (mg l-1) 1.2 F3 Americamysis bahia Moderado
Sediment dwelling organisms - Agudos 96 hora LC50 (mg l-1) - - -
Sediment dwelling organisms - Crónicos 28 día NOEC, estático, agua (mg l-1) 0.018 A5 Chironomus riparius Moderado
Sediment dwelling organisms - Crónicos 28 día NOEC, sedimento (mg kg-1) - - -
Plantas acuáticas - Agudos 7 día EC50, biomasa (mg l-1) - - -
Non-target plants - - -
- - -
Algas - Agudos 72 hora EC50, crecimiento (mg l-1) > 3.4 A5 Pseudokirchneriella subcapitata Moderado
Algas - Crónicos 96 hora NOEC, crecimiento (mg l-1) - - -
Abejas mielíferas Contacto aguda 48 hora LD50 (μg abeja-1) > 100 A5 Bajo
Oral aguda 48 hora LD50 (μg abeja-1) > 100 A5 Bajo
Modo desconocido aguda 48 hora LD50 (μg abeja-1) - - -
Lombrices - Agudos 14 día LC50 (mg kg-1) > 607 A5 Eisenia foetida Moderado
Lombrices - Crónicos 14 día NOEC, reproducción (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Causalidad - - -
Otro arthropoda (1) LR50 g ha-1 - - -
% Causalidad Inofensivo AA2 Typhlodromus pyri -
Otro arthropoda (2) LR50 g ha-1 - - -
% Causalidad Inofensivo AA2 Chrysoperla carnea -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 1.96 kg ha-1, 28 días
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


LA SALUD HUMANA Y PROTECCIÓN

for methoxyfenozide

General:
Propiedad Click here for information on the parameters used to describe human health and protection issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with human health and protection data Interpretación Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mamíferos - Agudos oral LD50 (mg kg-1) > 5000 A5 Rata Bajo
Mammals - Dermal LD50 (mg kg-1 body weight) 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 4.3 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
Consumo cada día aceptable (mg kg-1p.c. días-1) 0.1 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1p.c. días-1) 0.1 A5 Dog, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) 0.06 A5 Dog, SF=100 -
El nivel de exposición del operador (AOEL) sistemíco (mg kg-1p.c. días-1) 0.06 A5 Dog, SF=100 -
Estudios den la absorción cutánea (%) 0.5-8 A5 concentration dependent -
Directivo 76/464 Sustancias Peligrosas [Acceptable for proposed uses, PPE/PPC advised] - -
Limites de exposiciones - - -
Exposure Routes Public Low for propsoed uses
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutágeno Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

Cuestiones generales de la salud humana Potential endocrine effects on thyroid and adrenal glands at high doses
Possible liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Propiedad Click here for information on the parameters used to describe substance handling issues Valor Fuente/Cuenta de Cualidad/Otra Información Click here for information on the primary data sources used to populate this database with data on handling issues Interpretación Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
CLP classification 2013 Health: H315, H319
Environment: H412
CEE clasificación de riesgos Click here to view information omn the EU risk phrases N - Dangerous for the environment: R51/53
CEE clasificación sin riesgos Click here to view information omn the EU safety phrases -
Clasificación de OSM U - Es poco probable que presente un riesgo agudo
US EPA Classification (formulation) IV - Caution - Not acutely toxic
Número de las NU -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRADUCCIONES

for methoxyfenozide

Idioma Nombre
Inglés methoxyfenozide
Francés methoxyfenozide
Alemán Methoxyfenozid
Danés methoxyfenozid
Italiano metossifenozide
Español metoxifenocida
Griego -
Esloveno metoksifenozid
Polaco metoksyfenozyd
Sueco -
Húngaro metoxifenozid
Holandés -

Última actualización del registro: Monday 29 October 2018
Contacto: aeru@herts.ac.uk