spiroxamin (Ref: KWG 4168)
** spiroxamine ** Prevodi

Usoda v okolju - Ekotoksikologija - Cloveško zdravje - Abecedno kazalo - Domov

SPLOŠNE INFORMACIJE

Opis: A fungicide used to control powdery mildew, leaf spots, rusts and other diseases

Uvod: -

Direktive 1107/2009 (razveljavitvi 91/414):
Status Annex 1 (Re-review)
Dossier rapporteur/co-rapporteur Germany
Date inclusion expires 31/12/2010

Odobreno za uporabo () or known to be used () v sledecih evropskih državah:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also registered in: Avstralija

Osnovni status:
Vrsta fitofarmacevtskega sredstva Fungicid
Snov skupina Morpholine
Snov izvora Sinteticni
Nacin delovanja Systemic with protective, curative and eradicative action. Disrupts membrane function.
CAS RN 118134-30-8
EC številka -
CIPAC številka 572
US EPA kemicni kodo -
Chiral molecule Yes
Kemijska formula C18H35NO2
SMILES O1CC(OC12CCC(CC2)C(C)(C)C)CN(CC)CCC
International Chemical Identifier (InChI) InChI=1/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3
Ali je strukturni diagram na voljo/slika? Da
Molekulska masa (g mol-1) 297.5
IUPAC Ime 8-tert-butyl-1,4-dioxaspiro[4.5]decan-2-ylmethyl(ethyl)(propyl)amine
CAS Ime 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-methanamine
Druge informacije -
Herbicide Resistance Classification (HRAC) Neprimeren
Insecticide Resistance Classification (IRAC) Neprimeren
Fungicide Resistance Classification (FRAC) 5
Fizikalno stanje Pale yellow liquid
Related substances & organisms

Formulations:
Lastnost Vrednost
Example manufacturers of products using this active
  • Bayer CropScience
Example products using this active
  • Cello
  • Helix
  • Sage
  • Torch Extra
Status UK LERAP LERAP Category B (may vary with mixtures)
Formulation and application details Often supplied as an emulsifiable concentrate that is mixed with water and used as a spray.


USODA V OKOLJU

Lastnost Vrednost Vir / Stopnja kakovosti / Ostale informacije Razlaga
Topnost - v vodi pri 20oC (mg l-1) 405 A5 Srednji
Topnost - V organskih topilih pri 20oC (mg l-1) 200000 A5 - n-Heksan -
200000 A5 - Aceton -
200000 A5 - Metanol -
200000 A5 - Toluen -
Tališce (oC) -170 A5 -
Vrelišce (oC) Decomposes before boiling A5 -
Razgradnja point (oC) 120 A5 -
Plamenišce (oC) 147 A5 -
Koeficient porazdelitve oktanol-voda (log P) pri pH7, 20oC P 7.76 X 1002 Izracunano -
Log P 2.89 A5 Srednji
Volumska gostota (g ml-1) / Specificna teža 0.93 A5 -
Konstanta disociacije (pKa) pri 25oC 6.9 A5 -
Opomba: Osnova
Pritisk pare pri 25oC (mPa) 3.5 A5 Hlapen
Henrijeva konstanta pri 25oC (Pa m3 mol-1) 3.80 X 10-03 A5 Nehlapen
Henrijeva konstanta pri 20oC (dimensionless) 9.09 X 10-07 Q2 Zmerno haplen
GUS potencialni indeks izpiranja -0.23 Izracunano Nizko izpiranje
Model za podtalnico SCI-GROW (µg l-1) za 1 kg ha-1 or 1 l ha-1 odmerek Vrednost 5.35 X 10-03 Izracunano -
Opomba Ocenjene koncentracije sredstev s Koc vrednostmi višjimi od 9995 ml g-1 so nad obmocjem podatkov regresije, ki so bili uporabljeni pri razvoju SCI-GROW.
Potencial za prenos vezanih delcev - Izracunano Srednje
Maximum UV-vis absorption L mol-1 cm-1 No maximum of absorbance between 200nm - 400nm A5 -
Surface tension (mN m-1) - - -

Razgradnja:
Lastnost Vrednost Vir / Stopnja kakovosti / Ostale informacije Razlaga
Razgradnja v tleh (dnevi) (aerobic) DT50 (znacilno) 25 A5 Neobstojen
DT50 (v laboratoriju pri 20oC) 35 A5 Zmerno obstojen
DT50 (polje) 57.5 A5 Zmerno obstojen
DT90 (v laboratoriju pri 20oC) 100 A4 -
DT90 (polje) 153 A5 -
Opomba Field studies DT50 range 19.8-145.3 days, DT90 range 42.9-466.2 days
Fotoliza v vodi DT50 (dni) pri pH 7 Vrednost 50.5 A5 Stabilen
Opomba -
Hidroliza v vodi DT50 (dni) pri 20oC in pH 7 Vrednost Stabilen A5 Zelo obstojen
Opomba Stable pH 5 to pH 7, slow hydrolysis at pH 9
Vodni sediment DT50 (dni) 66.2 A5 Zmerno hiter
Vodna faza samo DT50 (dni) 0.8 A5 Hiter

Tla adsorpcija in mobilnosti:
Lastnost Vrednost Vir / Stopnja kakovosti / Ostale informacije Razlaga
Linear Kd - - -
Koc -
Opombe in obseg -
Freundlich Kf 142.3 A5 Nemobilen
Kfoc 14567
1/n 0.821
Opombe in obseg EU dossier kf range 4.61-892.6mL/g, Kfoc range 658.8-85008 mL/g, 1/n range 0.768-1.063, Soils=10
pH obcutljivost No

Key metabolites:
Metabolit Srednja Formacija Ocenjen Delež Maksimalne Pojav 91/414 Relevantnost
N-((8-tert-butyl-1,4-dioxaspiro(4.5)dec-2-yl)methyl)propan-1-amine Tla   0.088   Minor fraction, Not relevant
N-((8-tert-butyl-1,4-dioxaspiro(4.5)dec-2-yl)methyl)methyl]ethanamine Tla   0.092   Minor fraction, Not relevant

Other known metabolites:
Metabolite name and reference Aliases Srednja Formacija / Rate Ocenjen Delež Maksimalne Pojav Metabolising Enzymes
- spiroxamine docosanoic acid ester; Metabolite M35 Plant - -
- spiroxamine cyclohexenol; Metabolite M37 Plant - -
- spiroxamine N-formyl despropyl; Metabolite M38 Plant - -
2-(2-{[ethyl(propyl)amino]methyl}-1,4-dioxaspiro[4.5]dec-8-yl)-3-hydroxy-2-methylpropanoic acid
Opomba: C18H33NO5 		spiroxamine hydroxy acid; Metabolite M07 Animal (Liver) - -
t-butylcyclohexanone
Opomba: Secondary product 		- - - -
- N-formyl-desethyl spiroxamine; Metabolite M04 Plant - -
- N-oxide spiroxamine; Metabolite M03 Rat; Plant; Soil 0.110 -
2-(2-{[ethyl(propyl)amino]methyl}-1,4-dioxaspiro[4.5]dec-8-yl)-2-methylpropanoic acid
Opomba: C18H33NO4 		spiroxamine acid; Metabolite M06 Rat; Animal (Tissue, Milk, Eggs); Plant; Soil - -
- hydroxy spiroxamine; Metabolite M05 Rat; Animal; Plant; Soil - -
- 8-hydroxy acid spiroxamine; Metabolite M08 Rat; Animal - -
- spiroxamine hydroxy ketone conjugate; Metabolite M23 Plant - -
- spiroxamine diol diglycoside; Metabolite M24 Plant - -
- spiroxamine sulfate; Metabolite M25 Rat; Animal - -
- spiroxamine desethyl sulfate; Metabolite M26 Rat; Animal - -
- spiroxamine despropyl sulfate; Metabolite M27 Rat; Animal - -
- spiroxamine aminodiol; Metabolite M28 Rat; Plant - -
- spiroxamine aminodiol-N-oxide; Metabolite M29 Plant - -
- spiroxamine desethyl aminodiol; Metabolite M30 Plant - -
- spiroxamine despropyl aminodiol; Metabolite M31 Plant - -
- spiroxamine cychohexanol glucoside; Metabolite M32 Plant - -
2-(2-{[ethyl(propyl)nitroryl]methyl}-1,4-dioxaspiro[4.5]dec-8-yl)-2-methylpropyl hexopyranoside
Opomba: C15H29NO3 		hydroxy-despropyl spiroxamine; Metabolite M09 Plant - -
- hydroxy-N-oxide spiroxamine; Metabolite M10 Plant - -
- desethyl KWG4168; Metabolite M11 Rat; Animal; Plant; Soil - -
- despropyl acid spiroxamine; Metabolite M12 Rat; Plant; Soil - -
- cyclohexanol spiroxamine; Metabolite M13 Rat; Animal; Plant - -
- spiroxamine diol; Metabolite M14 Plant - -
- spiroxamine ketone; Metabolite M15 Rat; Plant; Soil - -
- spiroxamine hydroxy ketone; Metabolite M16 Plant - -
- spiroxamine acid glucuronide; Metabolite M19 Rat; Animal - -
- spiroxamine hydroxy-N-oxide glucoside; Metabolite M20 Plant - -
- spiroxamine hydroxy-N-oxide malonyl glucoside; Metabolite M21 Plant - -
- spiroxamine cyclohexanol glucuronide; Metabolite M22 Rat; Animal - -


EKOTOKSIKOLOGIJA

Lastnost Vrednost Vir / Stopnja kakovosti / Ostale informacije Razlaga
Faktor biokoncentracije BCF 79 A5 Nizek potencial
CT50 (dnevi) Nedostopen -
Potencial bioakumulacije - Izracunano Nizko
Sesalci - oralno akutno LD50 (mg kg-1) 460 A5 Miši Srednji
Sesalci - kratek izraz NOEL (mg kg-1) - A5 Podgana -
(ppm dieta) 30 -
Ptici - Akutno LD50 (mg kg-1) 565 A5 Colinus virginianus Srednji
Birds - Short term dietary (LC50/LD50) > 5000 mg kg feed-1 A5 Anas platyrhynchos -
Ribe - Akutno 96 ura LC50 (mg l-1) 7.13 A5 Lepomis macrochirus Srednji
Ribe - Kronicno 21 dni NOEC (mg l-1) 0.014 A5 Oncorhynchus mykiss -
Vodni nevretencarji - Akutno 48 ura EC50 (mg l-1) 6.1 A5 Daphnia magna Srednji
Vodni nevretencarji - Kronicno 21 dni NOEC (mg l-1) 0.1 A5 Daphnia magna -
Vodnih rakov - Acute 96 ura LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 ura LC50 (mg l-1) - - -
Sediment dwelling organisms - Kronicni 28 dan NOEC, static, voda (mg l-1) 3.2 A5 Chironomus riparius Srednji
Sediment dwelling organisms - Kronicni 28 dan NOEC, sediment (mg kg-1) - - -
Vodne rastline - Akutno 7 dni EC50, biomasa (mg l-1) 2.76 C4 Lemna gibba Srednji
Alge - Akutno 72 ura EC50, rast (mg l-1) 0.003 A5 Scenedemus subspicatus Visoko
Alge - Kronicno 96 ura NOEC, rast (mg l-1) 0.0002 Q2 Neznane vrste Visoko
Cebele - Acute 48 ura - LD50 (µg za cebele-1) 4.2 A5 Kontakt Srednji
Deževniki - Akutno 14 dan LC50 (mg kg-1) > 1000 A5 Srednji
Deževniki - Kronicno 14 dan NOEC, razmnoževanje (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50product ha
EC50product ha
NOECproduct ha
% Ucinek 		- - -
Ostali clenonožci (1) LR50 g ha-1 - - -
% Ucinek 77 Umrljivost
Dose: 0.75 kg ha-1
A5 Aphidius rhopalosiphi, licinke 		Zmerno škodljiv
Ostali clenonožci (2) LR50 g ha-1 - - -
% Ucinek 99 Umrljivost
Dose: 0.74 kg ha-1
A5 Typhlodromus pyri 		Škodljiv
Talni mikroorganizmi Mineralizacija dušika: Brez trajnega ucinka
Mineralizacija ogljika: Brez pomembnejšega ucinka 		A5
Dose: 7.5 l formulation/ha 		-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


CLOVEŠKO ZDRAVJE IN ZAŠCITA

Splošno:
Lastnost Vrednost Vir / Stopnja kakovosti / Ostale informacije Razlaga
Sesalci - oralno akutno LD50 (mg kg-1) 460 A5 Miši Srednji
Mammals - Dermal LD50 (mg kg-1 body weight) 1068 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 2.0 A5 Rat, 4hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Sprejemljiv dnevni vnos (mg kg-1bw dan-1) 0.025 A5 Dog, SF=100 -
ARfD - Referenca akutnega odmerka (mg kg-1bw dan-1) 0.1 A5 Rat, SF=100 -
AOEL - Sprejemljiva stopnja izpostavljenosti - Sistemski (mg kg-1) 0.015 A3 Rat, SF=167 -
Dermalne študije (%) 100 A3 default -
Direktiva o nevarnih snoveh 76/464 - - -
Meje izpostavljenosti - - -
Exposure Routes Public No unacceptable risks to bystanders identified
Occupational No unacceptable risks to operators or other workers identified
Primeri evropskih MRL (mejnih vrednosti ostankov FFS) (mg kg-1) Vrednost Grapes: 1.0; Barley grain and oat grain: 0.3; Vegetables, other fruit and other cereal grains: 0.05
Opomba Current May 2007.
For the EU pesticides database click here
MAC - najvišja, še sprejemljiva koncentracija v pitni vodi (µg l-1) - - -

Vprašanja zdravje:
Rakotvorna Mutagena Endokrini disruptor Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

Vprašanja vezana na zdravje cloveka No further information available

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

:
Lastnost Vrednost Vir / Stopnja kakovosti / Ostale informacije Razlaga
General Not explosive or oxidising
IMDG Transport Code is usually 6.1
CLP classification 2013 -
EC Klasifikacija Tveganja Xn - Harmful: R20/21/22
Xi - Irritant: R38, R43
N - Dangerous for the environment: R50, R53
EC Klasifikacija Varnosti S2, S36/37/39, S46, S60, S61
WHO klasifikacija II - Zmerno nevaren
US EPA Classification (formulation) II - Opozorilo - Zmerno strupena
UN Številka Usually 2902
Waste disposal & packaging Usually Packaging Group III (minor danger)


PREVODI

Jezik Ime
Anglešcina spiroxamine
Francošcina spiroxamine
Nemšcina Spiroxamine
Danšcina spiroxamin
Italijanšcina spiroxamina
Španšcina spiroxamina; espiroxamina
Gršcina spiroxamine
Slovenšcina spiroxamin
Poljšcina spiroksamina
Švedšcina -
Madžaršcina spiroxamin
Nizozemšcina spiroxamine
Zadnja posodobitev: nedelja 6. maj 2012
Kontakt: aeru@herts.ac.uk
© Copyright University of Hertfordshire