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chlorobenzilate (Ref: ENT 18596)
** chlorbenzylate ** chlorobenzylate ** G 23992 ** Translations

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SUMMARY

Chlorobenzilate is an insecticide with a narrow range of uses and is not approved for use in the EU. It has a low aqueous solubility but miscible with many organic solvents. It is volatile and has a low potential for leaching to groundwater. It is not expected to persist in soil systems. Chlorobenzilate has a low mammalian toxicity but there are some concerns regarding its potential for bio-concentration. It has a low toxicity to birds, a moderate toxicity for fish and honeybees.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for chlorobenzilate

Description: An obsolete non-systemic acaricide that was used to control mites on fruit and also in bee hives

Example pests controlled: Mites; Ticks

Example applications: Citrus; Walnuts; Beehives; Cotton; Grapes

Efficacy & activity: -

Availability status: Obsolete

Introduction & key dates: circa 1953

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism None
Chemical formula C16H14Cl2O3
Canonical SMILES CCOC(=O)C(C1=CC=C(C=C1)Cl)(C2=CC=C(C=C2)Cl)O
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) RAPBNVDSDCTNRC-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C16H14Cl2O3/c1-2-21-15(19)16(20,11-3-7-13(17)8-4-11)12-5-9-14(18)10-6-12/h3-10,20H,2H2,1H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide, Miticide
Substance group Organochlorine
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Nervous system toxin with contact action
CAS RN 510-15-6
EC number 208-110-2
CIPAC number 119
US EPA chemical code 028801
PubChem CID 10522
Molecular mass (g mol-1) 325.19
PIN (Preferred Identification Name) ethyl bis(4-chlorophenyl)hydroxyacetate
IUPAC name ethyl 4,4'-dichlorobenzilate
CAS name ethyl 4-chloro-α-(4-chlorophenyl)-a-hydroxybenzeneacetate
Other status information Chemical subject to PIC regulations; Rotterdam Convention (Class O); Phytotoxic to some top fruit.
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 2A
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Aculus pelekassi
Panonychus ulmi
Tetranychus mcdanieli
Tetranychus urticae
Galerucella birmanica
plus others
Physical state Colourless solid when pure
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Makhteshim-Agan
  • Ciba-Geigy AG
  • Nippon Kayaku
Example products using this active
  • Folbex smoke-strips
  • Kop-Mite
  • Akar
  • Acaraben
  • Folbex
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually supplied as an emulsifiable concentrate or as a wettable powder.


ENVIRONMENTAL FATE

for chlorobenzilate

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 10 G4 Low
Solubility - In organic solvents at 20oC (mg l-1) Miscible A4 - Acetone -
Miscible A4 - Methanol -
600000 A4 - Hexane -
Miscible A4 - Toluene -
Melting point (oC) 37 A4 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 3.80 X 1004 Calculated -
Log P 4.58 H4 High
Bulk density (g ml-1)/Specific gravity 1.33 Q2 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 0.12 G4 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.27 X 10-02 H4 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.72 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.27 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 23 G4 Non-persistent
DT50 (lab at 20oC) 20 Q2 Non-persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Best available data
Dissipation rate RL50 on plant matrix Value 10.8 R4 -
Note Published literature RL50 range 4.8-18.0 days, 2 citrus crops, various matrices, n=5
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - H3 Slightly mobile
Koc 2810
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for chlorobenzilate

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 750 Q2 Estimated Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 2784 G4 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 2250 F4 Anas platyrhynchos Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.7 G4 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.01 F2 Daphnia magna, LT50 High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) 1.01 A3 Moderate
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for chlorobenzilate

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 2784 G4 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) - - -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.02 JMPR 1980 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

General human health issues IARC Group 3 carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Incompatible with highly alkaline materials
CLP classification 2013 Health: H302
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S60, S61
WHO Classification O - Obsolete substance
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for chlorobenzilate

Language Name
English chlorobenzilate
French chlorobenzilate
German Chlorbenzilat
Danish chlorobenzilat
Italian clorobenzilato
Spanish clorbenzilato
Greek chlorobenzilate
Slovenian klorbensilat
Polish chlorobenzylat
Swedish -
Hungarian -
Dutch chloorbenzilaat

Record last updated: Tuesday 22 May 2018
Contact: aeru@herts.ac.uk
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