cycloate (Ref: R 2063) ** hexylthiocarbam ** Translations

Environmental Fate - Ecotoxicology - Human Health

GENERAL INFORMATION

Description: A herbicide used to control annual grass weeds and some broad-leaved weeds

Introduction: circa 1966

EC Directive 1107/2009 (repealing 91/414):

Status	Excluded from Annex 1
Dossier rapporteur/co-rapporteur	-
Date inclusion expires	Essential use only

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also registered in: USA

General status:

Pesticide type	Herbicide
Substance group	Thiocarbamate
Substance origin	Synthetic
Mode of action	Selective, systemic absorbed by roots and coleoptiles
CAS RN	1134-23-2
EC number	214-482-7
CIPAC number	214
US EPA chemical code	041301
Chemical formula	C11H21NOS
SMILES	O=C(SCC)N(CC)C1CCCCC1
International Chemical Identifier (InChI)	InChI=1/C11H21NOS/c1-3-12(11(13)14-4-2)10-8-6-5-7-9-10/h10H,3-9H2,1-2H3
Structure diagram/image available?	Yes
Molecular mass (g mol-1)	215.36
IUPAC Name	S-ethyl cyclohexyl(ethyl)thiocarbamate
CAS Name	S-ethyl cyclohexylethylcarbamothioate
Other status information	Potential groundwater contaminant
Herbicide Resistance Classification (HRAC)	N
Insecticide Resistance Classification (IRAC)	Not applicable
Fungicide Resistance Classification (FRAC)	Not applicable
Physical state	Colourless liquid
Related substances & organisms	-

Formulations:

Property	Value
Example manufacturers of products using this active	Helm Agro Tri-Ag AgroSan
Example products using this active	Ro-Neet Eurex Zephyr
UK LERAP status	No UK approval for use or outside scope
Formulation and application details	Usually supplied as an emulsifiable concentrate.

ENVIRONMENTAL FATE

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		75	K4	Moderate
Solubility - In organic solvents at 20oC (mg l-1)		-	-	-
Melting Point (oC)		11.5	Q3	-
Boiling Point (oC)		145	L2	-
Degradation point (oC)		-	-	-
Flashpoint (oC)		100	L3	-
Octanol-water partition coefficient at pH 7, 20oC	P	1.29 X 1004	Calculated	-
	Log P	4.11	T4	High
Bulk density (g ml-1)/Specific gravity		1.02	L3	-
Dissociation constant (pKa) at 25oC		-	-	-
		Note:
Vapour pressure at 25oC (mPa)		830	Q3	Volatile
Henry's law constant at 25oC (Pa m3 mol-1)		6.12 X 10-03	L3	Non-volatile
Henry's law constant at 20oC (dimensionless)		8.50 X 10-04	K3	Volatile
GUS leaching potential index		2.79	Calculated	Transition state
SCI-GROW groundwater index (µg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate	Value	2.35 X 10-01	Calculated	-
	Note	-
Potential for particle bound transport index		-	Calculated	Medium
Maximum UV-vis absorption L mol-1 cm-1		-	-	-
Surface tension (mN m-1)		-	-	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
Soil degradation (days) (aerobic)	DT50 (typical)	61	K4	Moderately persistent
	DT50 (lab at 20oC)	30	DW3	Moderately persistent
	DT50 (field)	-	-	-
	DT90 (lab at 20oC)	-	-	-
	DT90 (field)	-	-	-
	Note	General literature DT50: 9.4-133 days (R3)
Aqueous photolysis DT50 (days) at pH 7	Value	-	-	-
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	30	K4	Moderately persistent
	Note	-
Water-Sediment DT50 (days)		-	-	-
Water phase only DT50 (days)		-	-	-

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	H3	Moderately mobile
	Koc	272
	Notes and range	Best available data
Freundlich	Kf	-	-	-
	Kfoc	-
	1/n	-
	Notes and range	-
pH sensitivity		-

ECOTOXICOLOGY

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF	-	-	-
	CT50 (days)	-		-
Bioaccumulation potential		-	-	-
Mammals - Acute oral LD50 (mg kg-1)		> 2000	L3 Rat	Moderate
Mammals - Short term dietary NOEL	(mg kg-1)	-	L3 Rat	-
	(ppm diet)	55		-
Birds - Acute LD50 (mg kg-1)		2000	L3 Coturnix japonica	Moderate
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		4.5	L3 Oncorhynchus mykiss	Moderate
Fish - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		24	J4 Daphnia magna	Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		-	-	-
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees - Acute 48 hour LD50 (µg bee-1)		11	L2	Moderate
Earthworms - Acute 14 day LC50 (mg kg-1)		250	Q3	Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		-	-	-
Other soil macro-organisms - e.g. Collembola	LR50product ha EC50product ha NOECproduct ha % Effect	-	-	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		-	-	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Mammals - Acute oral LD50 (mg kg-1)		> 2000	L3 Rat	Moderate
Mammals - Dermal LD50 (mg kg-1 body weight)		> 5000	L3 Rabbit	-
Mammals - Inhalation LC50 (mg l-1)		4.7	L3 Rat	-
Other Mammal toxicity endpoints		-		-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		-	-	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		-	-	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		-	-	-
Dermal penetration studies (%)		-	-	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	-
	Occupational	-
Examples of European MRLs (mg kg-1)	Value	-
	Note	For the EU pesticides database click here
Drinking Water MAC (µg l-1)		-	-	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Acetyl cholinesterase inhibitor	Neurotoxicant	Respiratory tract irritant	Skin irritant	Eye irritant
	-	-
General human health issues		[No further information available]

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		[No information available]
EC Risk Classification		-
EC Safety Classification		-
WHO Classification		III	-	Slightly hazardous
US EPA Classification (formulation)		III	-	Caution - Slightly toxic
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS