INTERNATIONAL UNION
   OF PURE AND APPLIED
   CHEMISTRY
contact
1-methylcyclopropene
** 1-MCP ** MCP ** methylcyclopropene ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

1-methylcyclopropene is a plant growth regulator that has approval for use in the EU. It is moderately soluble in water, highly volatile and has some potential for leaching to groundwater. It is not persistent in soil systems but may, under certain conditions, persist in aquatic systems. It is relatively non-toxic to mammals, although it may bioaccumulate. There are gaps in knowledge regarding its toxicity to biodiversity but there is data showing that it is moderatly toxic to fish and algae. It is highly toxic to earthworms.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for 1-methylcyclopropene

Description: A gas used as a plant regulator to extend the life of cut and potted flowers, other ornamental plants and fruit.

Example pests controlled: Ripening processes

Example applications: Harvested fruit and vegetables especially apples; Ornamentals especially cutflowers, potted flowering plants, spring bedding, nursery andfoliage plants

Efficacy & activity: Efficiacy has been tested experimentally and in practice. The substance has been in active use for many years.

Availability status: Current

Introduction & key dates: 1999, USA

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur UK/Portugal
Date inclusion expires 31/10/2019
EU Candidate for substitution (CfS) Yes - low ADI / ARfD / AOEL
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA, Canada

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism None
Chemical formula C4H6
Canonical SMILES CC1=CC1
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) SHDPRTQPPWIEJG-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Plant growth regulator
Substance group Unclassified
Minimum active substance purity 960 g/kg
Known relevant impurities EU dossier - 3-CMP <0.5 g/kg; 1-CMP <0.5 g/kg; heptane
Substance origin Synthetic
Mode of action Inhibits the effecvts of ethylene on ripening
CAS RN 3100-04-7
EC number Not allocated
CIPAC number 767
US EPA chemical code 224459
PubChem CID 151080
Molecular mass (g mol-1) 54.09
PIN (Preferred Identification Name) -
IUPAC name 1-methylcyclopropene
CAS name 1-methylcyclopropene
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state Product is a white powder which then releases a colourless gas with faint sweet odour
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Landseer
  • Rohm and Hass
  • AgroFresh Inc,
  • Janssen
Example products using this active
  • SmartFresh
  • LupoFresh
  • EthylBloc
  • SmartTabs
UK LERAP status None
Formulation and application details Usually supplied in powder form for mixing with water which then releases the 1-MCP gas for fumigation within a closed space.


ENVIRONMENTAL FATE

for 1-methylcyclopropene

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 137 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 2450 A5 - n-Heptane -
2250 A5 - Xylene -
12500 A5 - Ethyl acetate -
11000 A5 - Methanol -
Melting point (oC) -100 A5 -
Boiling point (oC) 4.7 A4 -
Degradation point (oC) 260 A5 -
Flashpoint (oC) Not expected to self ignite; Flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 2.51 X 1002 Calculated -
Log P 2.4 A5 Low
Bulk density (g ml-1)/Specific gravity 0.634 F4 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 2.00 X 1008 A5 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 4.39 X 10-09 P4 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 2.79 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.34 X 10-01 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) Not applicable A5 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 15 A2 Non-persistent
DT50 (lab at 20oC) 15 A2 Non-persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier estimated data
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 5 to pH 9 at 20 deg C. Rapid at elevated temperatures ~50 deg C.
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - A2 Mobile
Koc 42.7
Notes and range EU dossier estimated data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for 1-methylcyclopropene

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 81 A5 Colinus virginianus High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) > 0.966 A4 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 0.776 A4 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) > 5.8 A5 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) > 0.838 A4 Selenastrum capricornutum Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) > 10.0 A5 Apis mellifera as inhallation toxicity, ppm Moderate
Earthworms - Acute 14 day LC50 (mg kg-1) 5.0 A5 Eisenia foetida, corr High
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 10.0 Mortality as ppm
A5 Aphidius rhopalosiphi
-
% Effect 30 Mortality
Dose: 10 mg l-1
A4 Aphidius rhopalosiphi, adult
-
Other arthropod (2) LR50 g ha-1 10.0 Mortality as ppm
A5 Typhlodromus pyri
-
% Effect 30 Mortality
Dose: 10 mg l-1
A4 Typhlodromus pyri, protonymph
-
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for 1-methylcyclopropene

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class Intermediate (class II) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 5.12 A5 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0009 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.07 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.009 A5 -
Dermal penetration studies (%) No data A5 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Minimal as normally only used inside commercial premises
Small risk from digestion of treated food commodities
Source: US EPA
Occupational Minimal - user should not be present during plant treatment which should be done in small enclosed spaces such as glasshouses
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) Not allocated A5 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues No further information available

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Avoid contact with oxidising agents
Flammable
CLP classification 2013 Health: H330
Handling: H220, H280
EC Risk Classification Click here to view information omn the EU risk phrases Carcinogen category 3: R40
N - Dangerous for the environment: R50/53
EC Safety Classification Click here to view information omn the EU safety phrases S23, S24/25, S36/37
WHO Classification NL - Not listed
US EPA Classification (formulation) IV (Oral), III (Dermal) - Caution - Not acutely toxic, Caution - Slightly toxic
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for 1-methylcyclopropene

Language Name
English 1-methylcyclopropene
French 1-methylcyclopropene
German 1-Methylcyclopropen
Danish 1-methylcyclopropene
Italian 1-metilciclopropene
Spanish 1-metilciclopropene
Greek -
Slovenian 1-metilciklopropen
Polish 1-metylocyklopropen
Swedish -
Hungarian -
Dutch 1-methylcyclopropeen

Record last updated: Monday 05 November 2018
Contact: aeru@herts.ac.uk
© University of Hertfordshire