dichlorophen |
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SUMMARY
Dichlorophen is a fungicide, herbicide, bactericide and algicide that is not approved for use in the EU. It has a low aqueous solubility and, based on its chemical properties, it is unlikely to leach to groundwater. It is not usually persistent in soils. Dichlorophen has a low mammalian toxicity but is moderately toxic to fish, aquatic invertebrates and algae. GENERAL INFORMATION
for dichlorophen
Description: A multiple purpose pesticide used to control various infections in agricultural and horticultural crops as well as in non-crop situations . Also has some applications as a veterinary treatment.
Example pests controlled: Red thread; Fusarium patch; Stem canker; Angular leaf spot; Cucumber wilt; Damping off; Root rot; Bulb riot; Web blotch
Example applications: Cotton; Peanuts; Potatoes; Vegetables including beans, onions, garlic; Tomatoes; Cucumbers; Ornamentals; Non-crop situations
Efficacy & activity: -
Availability status: Unknown
Introduction & key dates: First patented 1944 USA
EC Regulation 1107/2009 (repealing 91/414):
Status | Not approved |
Dossier rapporteur/co-rapporteur | Ireland |
Date inclusion expires | Expired |
EU Candidate for substitution (CfS) | Not applicable |
Listed in EU database | Yes |
Approved for use () or known to be used (
) in the following European countries:
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
Isomerism | None |
Chemical formula | C13H10Cl2O2 |
Canonical SMILES | C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O |
Isomeric SMILES | Clc1cc(c(O)cc1)Cc2cc(Cl)ccc2O |
International Chemical Identifier key (InChIKey) | MDNWOSOZYLHTCG-UHFFFAOYSA-N |
International Chemical Identifier (InChI) | InChI=1S/C13H10Cl2O2/c14-10-1-3-12(16)8(6-10)5-9-7-11(15)2-4-13(9)17/h1-4,6-7,16-17H,5H2 |
2D structure diagram/image available? | Yes |
Pesticide type | Fungicide, Algicide, Bactericide, Veterinary substance | |||
Substance group | Hetrocyclic | |||
Minimum active substance purity | - | |||
Known relevant impurities | - | |||
Substance origin | Synthetic | |||
Mode of action | Contact | |||
CAS RN | 97-23-4 | |||
EC number | 202-567-1 | |||
CIPAC number | 325 | |||
US EPA chemical code | 055001 | |||
PubChem CID | 3037 | |||
Molecular mass (g mol-1) | 269.1 | |||
PIN (Preferred Identification Name) | 2,2'-methylenebis(4-chlorophenol) | |||
IUPAC name | 4,4'-dichloro-2,2'-methylenediphenol | |||
CAS name | 2,2'-methylenebis[4-chlorophenol] | |||
Other status information | - | |||
Relevant Environmental Water Quality Standards | - | |||
Herbicide Resistance Classification (HRAC) | Not applicable | |||
Herbicide Resistance Classification (WSSA) | Not applicable | |||
Insecticide Resistance Classification (IRAC) | Not applicable | |||
Fungicide Resistance Classification (FRAC) | Not known | |||
Examples of recorded resistance | - | |||
Physical state | Colourless crystals | |||
Related substances & organisms | - |
Formulations:
ENVIRONMENTAL FATE
for dichlorophen
Property ![]() |
Value | Source/Quality Score/Other Information ![]() |
Interpretation ![]() |
|
Linear | Kd | - | Q2 | Non-mobile |
Koc | 4103 | |||
Notes and range | Estimated | |||
Freundlich | Kf | - | - | - |
Kfoc | - | |||
1/n | - | |||
Notes and range | - | |||
pH sensitivity | - |
ECOTOXICOLOGY
for dichlorophen
HUMAN HEALTH AND PROTECTION
for dichlorophen
General:
Property ![]() |
Value | Source/Quality Score/Other Information ![]() |
Interpretation ![]() |
|
Threshold of Toxicological Concern (Cramer Class) ![]() |
High (class III) | - | - | |
Mammals - Acute oral LD50 (mg kg-1) | 2690 | L3 Rat | Low | |
Mammals - Dermal LD50 (mg kg-1 body weight) | > 1000 | L3 Mouse | - | |
Mammals - Inhalation LC50 (mg l-1) | - | - | - | |
Other Mammal toxicity endpoints | Intravenous DT50 = 17.0 mg kg-1 | V3 Rat | - | |
ADI - Acceptable Daily Intake (mg kg-1bw day-1) | - | - | - | |
ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
Dermal penetration studies (%) | - | - | - | |
Dangerous Substances Directive 76/464 | - | - | - | |
Exposure Limits | - | - | - | |
Exposure Routes | Public | Low risk to Europeans as no longer approved for use | ||
Occupational | Low risk to Europeans as no longer approved for use | |||
European MRLs | Click here for the EU MRL pesticide database | |||
Drinking Water Standards | - | - | - | |
Drinking Water MAC (μg l-1) | - | - | - |
Health issues:
Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
- |
- |
|||||||
Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
- |
|
|||||||
General human health issues | Moderately toxic |
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
Language | Name |
English | dichlorophen |
French | dichlorophene |
German | Dichlorophen |
Danish | dichlorophen |
Italian | diclorofene |
Spanish | diclorofen |
Greek | dichlorophen |
Slovenian | diklorofen |
Polish | dichlorofen |
Swedish | - |
Hungarian | - |
Dutch | dichlorofeen |
Record last updated: Tuesday 22 May 2018
Contact: aeru@herts.ac.uk
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