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diuron (Ref: DPX 14740)
** dichlorfenidim ** Translations

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SUMMARY

Diuron is a pre-emergence herbicide that is approved for use in the EU. It has a low aqueous solubility, a low volatility and may, under certain conditions, leach to groundwater. It may be moderately persistent in soil systems and may also persist in water. It is moderately toxic to mammals and is classified as an irritant, It is moderately toxic to birds, earthworms, most aquatic species but is slightly more toxic to algae. It has a low toxicity to honeybees.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for diuron

Description: A pre-emergence residual herbicide for total control of weeds and mosses in a variety of agricultural and non-agricultural situations

Example pests controlled: Bermudagrass; Fathen; Pigweed; Charlock; Sowthistle; Wild radish; Wild turnip; Capeweed; Deadnettles; Poppies; Barnyard grass

Example applications: Vegetables including asparagus, peas, pulses; Fruit including bananas, pineapples, grapes; Cotton; Lucerne; Lupins; Sugarcane; Cereals including wheat, barley, oats, triticale; Tea; Ornamentals including tulips, daffodils, iris

Efficacy & activity: Efficiacy fully demonstratedvia field trials and through extensive use.

Availability status: Current

Introduction & key dates: circa 1951

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Germany/Denmark
Date inclusion expires 30/09/2019
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C9H10Cl2N2O
Canonical SMILES CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) XMTQQYYKAHVGBJ-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)
2D structure diagram/image available? Yes

Click to access the Cambridge Crystallographic Data Centre (CCDC) website
Cambridge Crystallographic Data Centre diagrams:
Common Name Relationship Link
Diuron - Click here for the CCDC structure diagram

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Phenylamide
Minimum active substance purity 970 g/kg
Known relevant impurities EU dossier - 3,4-dichloroaniline; 2,4,3',4'-tetrachloroazoxybenzene; 3,4,3',4'-tetratchloroazobenzene
Substance origin Synthetic
Mode of action Systemic, absorbed via roots, acts by strongly inhibiting photosynthesis
CAS RN 330-54-1
EC number 206-354-4
CIPAC number 100
US EPA chemical code 035505
PubChem CID 3120
Molecular mass (g mol-1) 233.09
PIN (Preferred Identification Name) N'-(3,4-dichlorophenyl)-N,N-dimethylurea
IUPAC name 3-(3,4-dichlorophenyl)-1,1-dimethylurea
CAS name N'-(3,4-dichlorophenyl)-N,N-dimethylurea
Other status information WFD priority substance; Potential groundwater contaminant; Possible drinking water contaminant
Relevant Environmental Water Quality Standards EU Directive 2008/105/EC EQS surface waters: annual average 0.2 ug/L; max measured 1.8 ug/L
UK Environment Agency non-statutory standard for the protection of aquatic life in freshwater and saltwater: 2 ug/L as annual average; Freshwater 20 ug/L as max acceptable conc.
Herbicide Resistance Classification (HRAC) C2
Herbicide Resistance Classification (WSSA) 7
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state Off-white powder
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer Environ
  • Headland
  • Makhteshim-Agan
  • Nomix Environ
  • Nufarm
Example products using this active
  • Divide
  • Diurex
  • Freeway
  • Karmex
  • Diuron 900DF
  • Diuron 80% SC
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Often supplied as a soluble concentrate or wettable powder that is mixed with water and applied as a spray.


ENVIRONMENTAL FATE

for diuron

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 35.6 A5 - ar 35 degC Low
Solubility - In organic solvents at 20oC (mg l-1) 1470 A5 - o-Xylene -
47200 A5 - Acetone -
19000 A5 - Ethyl acetate -
14400 A5 - 1,2-Dichloroethane -
Melting point (oC) 157.2 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 330 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 7.41 X 1002 Calculated -
Log P 2.87 A5 Moderate
Bulk density (g ml-1)/Specific gravity 1.5 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 1.15 X 10-03 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.00 X 10-06 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 2.43 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.50 X 10-01 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 Neutral pH: 210nm=29414, 248nm=18516, 290nm=1002
Acidic pH: 211nm=29433, 248nm=18697
Basic pH: 220nm=21465, 248nm=16935
A5 -
Surface tension (mN m-1) 72.1 A5 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability Not readily biodegradable
Soil degradation (days) (aerobic) DT50 (typical) 146.6 A5 Persistent
DT50 (lab at 20oC) 146.6 A5 Persistent
DT50 (field) 229 A5 Persistent
DT90 (lab at 20oC) 516.1 A5 -
DT90 (field) 2000 A4 -
DT50 modelling endpoint 116.5 A5 normalised geometric mean of lab studies, dark aerobic conditions -
Note EU dossier 2018 lab studies DT50 range 27.3-472 days, DT90 range 90.8-1570 days, soils=7; field studies DT50 range 54-792 days, DT90 range 180 - >10,000 days, Soils=6 days, 7 soils
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 43 A5 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 4 to pH 9
Water-sediment DT50 (days) 48 A4 Moderately fast
Water phase only DT50 (days) 8.8 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd 12.8 A5 Slightly mobile
Koc 680
Notes and range EU 2018 dossier Kd range 7.7-20.4 mL/g, Koc range 543-956 mL/g; Other sources: Koc = 238-1750 mL/g, Soils=10
Freundlich Kf 7.0 A5 Slightly mobile
Kfoc 757
1/n 0.75
Notes and range EU 2018 dossier kf range 4.48-12.52 mL/g, Kfoc range 293-504 mL/g, 1/n range 0.67-0.89, Soils=5; Other sources: Kfoc range 293-909 mL/g, Soils=14
pH sensitivity None

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
1-(3,4-dichlorophenyl)-3-methylurea This metabolite may cause environmental pollution, click here for further information Soil   0.330   Major fraction, Relevant
3,4-dichlorophenyl urea This metabolite may cause environmental pollution, click here for further information Soil   0.245   Major fraction, Relevant
3,4-dichloroaniline Soil   0.02   Minor fraction, Not relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
N'-(3-chlorophenyl)-N,Ndimethylurea mCPDMU Soil; Water - -


ECOTOXICOLOGY

for diuron

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 9.45 R3 (Whole body) Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) > 250 -
Birds - Acute LD50 (mg kg-1) 1104 A5 Colinus virginianus Moderate
Birds - Short term dietary (LC50/LD50) 1730 mg kg feed-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 6.7 A5 Cyprinodon variegatus Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.41 A4 Oncorhynchus mykiss, 28 day Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 5.7 L3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.096 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 1.1 A5 Americamysis bahia Moderate
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.0183 A5 Lemna gibba Moderate
Non-target plants 4.15 A5 Lycopersicom esulentum
Vegetative vigour
as g/ha
-
136 A5 Lycopersicom esulentum
Seedling mergence
as g/ha
-
Algae - Acute 72 hour EC50, growth (mg l-1) 0.0027 F4 Scenedesmus quadricauda High
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 101.7 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 86.75 A5 Moderate
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 798 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 15.78 A5 Eisenia foetida, corr Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect 703 R4 Folsomia candida, NOECL 10.0 mg kg-1 -
Other arthropod (1) LR50 g ha-1 - - -
% Effect 5 Mortality
Dose: 5 kg ha-1
A5 Aphidius rhopalosiphi
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 0
5
Mortality
Reproduction
Dose: 5 kg ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 4 kg ha-1
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for diuron

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 0.26 / 7.1 A5 Rat (aerosol / dust) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.003 A5 Rat, SF=200 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.016 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) No data - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.007 A5 Rat, SF=100 -
Dermal penetration studies (%) 0.5-7.0 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Limits [UK LT TWA 8 hr: 1.0 mg/m3] UK EA QS database, 2018 -
Exposure Routes Public Risks to bystanders and residents estimated to be low considering current use profile
Occupational Risks of exposure identified via modelling - PPE/PPC essential
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

General human health issues Possible blood, kidney, bladdrr, spleen and liver toxicant
Endocrine issues - Inhibition of androgens action

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H302, H351, H373
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases Carcinogen category 3: R40
Xn - Harmful: R22, R48/22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S13, S22, S23, S36, S46, S60, S61
WHO Classification III - Slightly hazardous
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number Usually 3077
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for diuron

Language Name
English diuron
French diuron
German Diuron
Danish diuron
Italian diuron
Spanish diuron
Greek diuron
Slovenian diuron
Polish diuron
Swedish -
Hungarian diuron
Dutch diuron

Record last updated: Tuesday 30 October 2018
Contact: aeru@herts.ac.uk
© University of Hertfordshire