IUPAC AGROCHEMICAL
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dodemorph
** doazine ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for dodemorph

Description: A fungicide for powdery mildew control

Introduction: circa 1967

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Netherlands
Date inclusion expires 31/08/2019

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Fungicide
Substance group Morpholine (isomer mix)
Substance origin Synthetic
Mode of action Systemic with protective and curative action
CAS RN 1593-77-7
EC number 216-474-9
CIPAC number 300
US EPA chemical code 268600
Chiral molecule Chiral or specific isomer of chiral molecule
Chemical formula C18H35NO
SMILES O2C(CN(C1CCCCCCCCCCC1)CC2C)C
International Chemical Identifier (InChI) InChI=1/C18H35NO/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18/h16-18H,3-15H2,1-2H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 281.48
PIN (Preferred Identification Name) 4-cyclododecyl-2,6-dimethylmorpholine
IUPAC name 4-cyclododecyl-2,6-dimethylmorpholine
CAS name 4-cyclododecyl-2,6-dimethylmorpholine
Other status information -
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 5
Physical state Colourless solid (cis-isomer)
Related substances & organisms -

Formulations:
Property Value
Example manufacturers of products using this active -
Example products using this active -
UK LERAP status No UK approval for use or outside scope
Formulation and application details -


ENVIRONMENTAL FATE

for dodemorph

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 100 A4 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 50000 L3 - Ethanol -
1000000 L3 - Chloroform -
57000 L3 - Acetone -
185000 L3 - Ethyl acetate -
Melting point (oC) 41.5 A4 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 3.98 X 1004 Calculated -
Log P 4.6 A5 High
Bulk density (g ml-1)/Specific gravity 0.89 Q2 -
Dissociation constant (pKa) at 25oC 8.08 L3 -
Note: Weak acid
Vapour pressure at 25oC (mPa) 0.48 L3 Non-volatile
Henry's law constant at 25oC (Pa m3 mol-1) 7.70 X 10-01 L3 Moderately volatile
Henry's law constant at 20oC (dimensionless) 1.40 X 10-07 K3 Non-volatile
GUS leaching potential index -0.65 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 41 W4 Moderately persistent
DT50 (lab at 20oC) 41 A5 Moderately persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note EU dossier lab studies DT50 range 24 (loamy sand) - 125 (sandy loam) days
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) 53 A5 Moderately fast
Water phase only DT50 (days) 1.3 A5 Moderately fast

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 224 A5 Non-mobile
Kfoc 25200
1/n 0.855
Notes and range EU dossier kf range 54-336, 1/n range 0.742-0.945, Soils=4 - EU dossier value for dodemorph acetate. Research literature range 4200-48000 mL/g
pH sensitivity -


ECOTOXICOLOGY

for dodemorph

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF - - -
CT50 (days) - -
Bioaccumulation potential - - -
Mammals - Acute oral LD50 (mg kg-1) > 4100 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) - - -
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 2.2 L2 Poecilia reticulata Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 3.34 L3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 17.9 K3 Unknown species Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for dodemorph

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) > 4100 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 1640 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.082 A5 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.33 A5 Rabbit, SF=100 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.033 A5 Dog, SF=100 -
Dermal penetration studies (%) 2.7-20.0 A5 concentration dependant -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Negligible risk to bystanders
Occupational Risk to operators and other farm works acceptable when PPE/PPC is used
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 Calc MAC=2.5 g/l -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

-

General human health issues Skin sensitiser

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General Corrosive
CLP classification 2013 -
EC Risk Classification Xi - Irritant: R36/37/38
N - Dangerous for the environment: R51, R53
EC Safety Classification S2, S26, S61
WHO Classification III - Slightly hazardous
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for dodemorph

Language Name
English dodemorph
French dodemorphe
German Dodemorph
Danish dodemorph
Italian dodemorf
Spanish dodemorf
Greek dodemorph
Slovenian dodemorf
Polish dodemorf
Swedish -
Hungarian -
Dutch dodemorf

Record last updated: Saturday 02 August 2014
Contact: aeru@herts.ac.uk
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