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dodemorph
** doazine ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for dodemorph

Description: A fungicide for powdery mildew control

Example pests controlled: Powdery mildews

Example applications: Ornamentals including greenhouse and field-grown roses

Availability status: Current

Introduction & key dates: circa 1967

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Netherlands
Date inclusion expires 31/08/2019

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide
Substance group Morpholine (isomer mix)
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Systemic with protective and curative action. Inhibits sterol biosynthesis in membranes
CAS RN 1593-77-7
EC number 216-474-9
CIPAC number 300
US EPA chemical code 268600
Chiral molecule Chiral, a specific isomer or a derivative of a chiral molecule
Chemical formula C18H35NO
SMILES O2C(CN(C1CCCCCCCCCCC1)CC2C)C
International Chemical Identifier key (InChIKey) JMXKCYUTURMERF-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C18H35NO/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18/h16-18H,3-15H2,1-2H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 281.48
PIN (Preferred Identification Name) 4-cyclododecyl-2,6-dimethylmorpholine
IUPAC name 4-cyclododecyl-2,6-dimethylmorpholine
CAS name 4-cyclododecyl-2,6-dimethylmorpholine
Other status information -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 5
Examples of recorded resistance -
Physical state Colourless solid (cis-isomer)
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • BASF
  • Mallinckrodt
Example products using this active
  • Meltatox
  • Milban
  • Cyclomorph
UK LERAP status No UK approval for use or outside scope
Formulation and application details Usually supplied as an emulsifiable concentrate.


ENVIRONMENTAL FATE

for dodemorph

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 100 A4 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 50000 L3 - Ethanol -
1000000 L3 - Chloroform -
57000 L3 - Acetone -
185000 L3 - Ethyl acetate -
Melting point (oC) 41.5 A4 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 3.98 X 1004 Calculated -
Log P 4.6 A5 High
Bulk density (g ml-1)/Specific gravity 0.89 Q2 -
Dissociation constant (pKa) at 25oC 8.08 L3 -
Note: Weak acid
Vapour pressure at 25oC (mPa) 0.48 L3 Volatile
Henry's law constant at 25oC (Pa m3 mol-1) 7.70 X 10-01 L3 Moderately volatile
Henry's law constant at 20oC (dimensionless) 1.40 X 10-07 K3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.65 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
Soil degradation (days) (aerobic) DT50 (typical) 41 W4 Moderately persistent
DT50 (lab at 20oC) 41 A5 Moderately persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note EU dossier lab studies DT50 range 24 (loamy sand) - 125 (sandy loam) days
Plant matrix DT50 (days) Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) 53 A5 Moderately fast
Water phase only DT50 (days) 1.3 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 224 A5 Non-mobile
Kfoc 25200
1/n 0.855
Notes and range EU dossier kf range 54-336, 1/n range 0.742-0.945, Soils=4 - EU dossier value for dodemorph acetate. Research literature range 4200-48000 mL/g
pH sensitivity -


ECOTOXICOLOGY

for dodemorph

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) - - -
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 4100 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) - - -
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 2.2 L2 Poecilia reticulata Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 3.34 L3 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 17.9 K3 Unknown species Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 76.6 A5 Moderate
Oral acute 48 hour LD50 (μg bee-1) > 106.3 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for dodemorph

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 4100 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 1640 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.082 A5 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.33 A5 Rabbit, SF=100 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.033 A5 Dog, SF=100 -
Dermal penetration studies (%) 2.7-20.0 A5 concentration dependant -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Negligible risk to bystanders
Occupational Risk to operators and other farm works acceptable when PPE/PPC is used
European MRLs Click here for the EU MRL pesticide database
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 Calc MAC=2.5 μg l-1 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Some potential as a skin sensitiser

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Corrosive
CLP classification 2013 Health: H315, H319, H335
Environment: H411
EC Risk Classification Click here to view information omn the EU risk phrases Xi - Irritant: R36/37/38
N - Dangerous for the environment: R51, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S26, S61
WHO Classification III - Slightly hazardous
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for dodemorph

Language Name
English dodemorph
French dodemorphe
German Dodemorph
Danish dodemorph
Italian dodemorf
Spanish dodemorf
Greek dodemorph
Slovenian dodemorf
Polish dodemorf
Swedish -
Hungarian -
Dutch dodemorf

Record last updated: Friday 18 March 2016
Contact: aeru@herts.ac.uk
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