Parathion-ethyl (Ref: OMS 19) |

Last updated: 28/02/2025
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(Also known as: parathion; thiophos; ethyl parathion; BAY 9491; ENT 15108; AC 3422) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A broad-spectrum insecticide and acaricide used to control sucking and chewing insects and mites |
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Aphids; Mealybugs; Codling moth; Scale, Leafhoppers |
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Alfalfa; Barley; Rapseed; Cotton; Sorghum; Soybeans; Sunflowers; Wheat; Broccoli; Brussel sprouts |
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- |
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Considered obsolete but may be available in some countriesl Banned in many countries |
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circa 1950, introduced |
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Not approved |
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Expired |
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No UK approval for use as a pesticide |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Italy |
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Expired |
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Not applicable |
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Yes |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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None |
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C₁₀H₁₄NO₅PS |
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CCOP(=S)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-] |
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No data |
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LCCNCVORNKJIRZ-UHFFFAOYSA-N |
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InChI=1S/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3 |
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Yes |
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Insecticide, Acaricide |
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Organophosphate insecticide; Organophosphate acaricide; Organothiophosphate insecticide; Organothiophosphate acaricide |
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- |
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- |
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Synthetic |
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Non-systemic with contact, stomach and some respiratory action. Acetylcholinesterase (AChE) inhibitor. |
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56-38-2 |
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200-271-7 |
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10 |
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057501 |
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991 |
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015-034-00-1 |
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291.27 |
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O,O-diethyl-O-4-nitrophenyl phosphorothioate |
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O,O-diethyl O-4-nitrophenyl phosphorothioate |
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O,O-diethyl O-(4-nitrophenyl) phosphorothioate |
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Potential groundwater contaminant; Marine Pollutant; Rotterdam Convention (Class Ia) - subject to PIC regulations Annex III; Subject to the provisions of the UK Poisons Act 1972 |
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- |
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Not applicable |
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Not applicable |
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1B |
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Not applicable |
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Adoxophyes orana, Aedes dorsalis, Aedes melanimon, Aedes nigromaculis, Amblyseius potentillae, Bemisia tabaci, many others |
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White crystalline solid with foul odour when pure. technical substance may be a pale yellow liquid |
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- Bayer Crop Protection
- Monsanto
- Cheminova
- King Tech
- Fujian Sannong Group Co. Ltd.
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- Folidol E
- Niran
- Woprophos
- Fighter
- Co-thion
- Alkron
- Vitrex
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Available in a variety of formulations including dusts, emulsion concentrates, granules, ULV liquids and wettable powders |
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12.4 |
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Moderate |
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200000 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Dichloromethane |
- |
200000 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Toluene |
- |
75000 |
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source Hexane |
- |
200000 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Isopropanol |
- |
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6.1 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
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375 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
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- |
- |
- |
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174 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
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6.76 X 1003 |
Calculated |
- |
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3.83 |
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High |
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Soluble |
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- |
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Regulatory data - observed in metabolism and farm animal feeding studies |
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- |
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1.26 |
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- |
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- |
- |
- |
- |
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0.89 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Low volatility. If applied directly to plants, drift is a concern & mitigation is advisable |
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3.02 X 10-02 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-volatile |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
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49 |
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Moderately persistent |
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14 |
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Non-persistent |
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17 |
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Non-persistent |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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ICULID datasheet DT₅₀ lab studies 3-32 days, field studies DT₅₀ range 2-58 days; Other sources: 7DT₅₀ -10 days (R3) |
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3.8 |
R4 R = Peer reviewed scientific publications 4 = Verified data |
- |
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Published literature RL₅₀ range 0.2-19.6 days, wide range of field grown crops and wide range of matrics, n=30 |
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5.1 |
- |
- |
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Published literature RL₅₀ range 0.7-31.1 days, wide range of field grown crops and wide range of matrics, n=32 |
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30 |
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Stable |
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- |
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260 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Persistent |
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pH sensitive: DT₅₀ 272 days at pH 4, 130 days at pH 9, all at 22 °C |
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4.3 |
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Fast |
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3.5 |
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Moderately fast |
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- |
- |
- |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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- |
Soil adsorption and mobility |
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- |
H3 H = The US ARS pesticide properties database. Dataset is no longer available. 3 = Unverified data of known source |
Non-mobile |
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7660 |
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Other sources: 316.2-15849 mL g⁻¹ (R3) |
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17 |
R4 R = Peer reviewed scientific publications 4 = Verified data |
Slightly mobile |
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580 |
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0.95 |
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Kf range 13.0-21.0 (229 for peat) mL g⁻¹, Kfoc range 491-636 (355 for peat) mL g⁻¹, 1/n - no data, Soils=4 |
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- |
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1.52 |
Calculated |
Low leachability |
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3.32 X 10-02 |
Calculated |
- |
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- |
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Low |
Calculated |
- |
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Non-mobile |
Calculated |
- |
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- |
- |
- |
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40 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data (Other literature values Log BCF range 1.1-1.9 (R3)) |
Low potential |
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<0.5 |
- |
None
Terrestrial ecotoxicology |
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13 |
Rat |
High |
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- |
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source Rat 2 yr |
- |
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2 |
- |
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- |
- |
- |
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2.1 |
Anas platyrhynchos |
High |
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- |
- |
- |
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- |
- |
- |
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> 267 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Eisenia foetida |
Moderate |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
- |
- |
- |
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- |
- |
- |
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> 0.21 |
R4 R = Peer reviewed scientific publications 4 = Verified data Apis mellifera |
High |
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> 0.175 |
Apis mellifera |
High |
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- |
- |
- |
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[The residual time to 25% mortality (RT25) value for honeybees is 24 hrs - USEPA data] |
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- |
- |
- |
- |
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- |
- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
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- |
- |
- |
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- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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Harmful |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source Typhlodromus pyri |
- |
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- |
- |
- |
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1.5 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Oncorhynchus mykiss |
Moderate |
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> 0.098 |
P3 P = Other non-EU, UK or US Governments and Regulators 3 = Unverified data of known source Danio rerio |
Moderate |
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> 4.96 |
Danio rerio |
Moderate |
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0.0025 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Daphnia magna |
High |
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0.0001 |
P3 P = Other non-EU, UK or US Governments and Regulators 3 = Unverified data of known source Daphnia magna |
High |
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0.0002 |
Ceriodaphnia dubia |
High |
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0.00011 |
Americamysis bahia |
High |
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0.14 |
Chironomus riparius 1 day |
Moderate |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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16.3 |
R4 R = Peer reviewed scientific publications 4 = Verified data Myriophyllum aquaticum |
Low |
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10.0 |
Scenedesmus subspicatus |
Moderate |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
HUMAN HEALTH AND PROTECTION |
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High (class III) |
- |
- |
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13 |
Rat |
High |
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71.0 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat |
- |
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0.03 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat (aerosol) |
- |
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- |
- |
- |
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0.0006 |
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- |
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0.005 |
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- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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List I; List II |
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- |
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- |
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- |
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EU MRL pesticide database |
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- |
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EU Drinking Water standards: A1 waters: 0.001 mg l⁻¹, A2 waters 0.0025 mg l⁻¹, A3 waters: 0.005 mg l⁻¹ EU Directive for the protection of shelfish intended for human consumption: 100 µg l⁻¹ |
UK EA QS database 2018 |
- |
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- |
- |
- |
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- |
- |
- |
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Carcinogen |
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Endocrine disruptor |
?Possibly, status not identified |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E1 E = Unspecified genotoxicity type (miscellaneous data source) 1 = Positive |
?Possibly, status not identified |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
✓Yes, known to cause a problem |
No data found |
XNo, known not to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
XNo, known not to cause a problem |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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Highly toxic Possible brain toxicant US EPA - Group C carcinogen, possible human carcinogen |
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IMDG Transport Hazard Class 6.1 |
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Health: H300, H311, H330, H372 Environment: H400, H410 |
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Ia (Extremely hazardous) |
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UN2810 |
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Packaging Group I (great danger) |
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Chemically stable under standad ambient conditions |
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parathion-ethyl |
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parathion |
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Parathion |
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parathion |
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paration |
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paratión |
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parathion |
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paration |
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- |
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parathion |
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Record last updated: |
28/02/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |