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thiacloprid (Ref: YRC 2894)
** Translations

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GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for thiacloprid

Description: A chloronicotinyl insecticide for use on apples and other crops to control sucking and chewing insects

Example pests controlled: Aphids; Pollen beetles; Blossom midge; codling moth

Example applications: Apples; Pears; Some citrus crops; Brussel sprouts; Cabbage; Cauliflower; Carrot; Parsnip; Peas; Potato; Oilseed rape

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1999, first registered Brazil; 2003 USA

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires 30/04/2017

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Molluscicide
Substance group Neonicotinoid
Minimum active substance purity 975 g/kg
Known relevant impurities EU and FAO dossiers - None declared
Substance origin Synthetic
Mode of action Contact and stomach action with some systemic properties. Acetylcholine receptor (nAChR) agonist.
CAS RN 111988-49-9
EC number -
CIPAC number 631
US EPA chemical code 014019
Chiral molecule No
Chemical formula C10H9CIN4S
SMILES Clc1ncc(cc1)CN2C(=N\C#N)\SCC2
International Chemical Identifier key (InChIKey) HOKKPVIRMVDYPB-UVTDQMKNSA-N
International Chemical Identifier (InChI) InChI=1S/C10H9ClN4S/c11-9-2-1-8(5-13-9)6-15-3-4-16-10(15)14-7-12/h1-2,5H,3-4,6H2/b14-10-
Structure diagram/image available? Yes
Molecular mass (g mol-1) 252.72
PIN (Preferred Identification Name) {(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
IUPAC name (Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidin-2-ylidenecyanamide
CAS name (Z)-(3-((6-chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)cyanamide
Other status information NOTE ban or usage restriction may be in place for use on flowering crops in some Member States
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 4A
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Leptinotarsa decemlineata
Physical state White to beige crystalline powder
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Scotts
  • Standon
Example products using this active
  • Biscaya
  • Calypso
  • Exemptor
  • Topstar
UK LERAP status None (may vary with mixtures)
Formulation and application details Formulations include oil dispersions, soluble concentrates and granules.


ENVIRONMENTAL FATE

for thiacloprid

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 184 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 100 A5 - n-Hexane -
300 A5 - Xylene -
64000 A5 - Acetone -
9400 A5 - Ethyl acetate -
Melting point (oC) 136 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 270 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.82 X 1001 Calculated -
Log P 1.26 A5 Low
Bulk density (g ml-1)/Specific gravity 1.46 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 25oC (mPa) 3.00 X 10-07 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 5.00 X 10-10 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.14 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 3.79 X 10-04 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 No absorption above 290nm A3 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 15.5 A5 Non-persistent
DT50 (lab at 20oC) 1.3 A5 Non-persistent
DT50 (field) 18 A5 Non-persistent
DT90 (lab at 20oC) 8.9 A5 -
DT90 (field) 45 A5 -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 0.7-5 days, DT90 range 2.3-15.5 days, field studies DT50 range 9-27 days, DT90 range 31-91 days; Other sources: 15 days
Dissipation rate RL50 on plant matrix Value 8.8 R4 -
Note Published literature RL50 range 1.1-11.3 days, 3 field grown crops, various matrices, n=4
Dissipation rate RL50 on and in plant matrix Value 3.8 R4 -
Note Published literature RL50 range 0.7-9.0 days, 9 field & undercover grown crops, various matrices, n=13
Aqueous photolysis DT50 (days) at pH 7 Value Stable A5 -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 5 to pH 9
Water-sediment DT50 (days) 28 A5 Fast
Water phase only DT50 (days) 8.5 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 4.41 A5 Slightly mobile
Kfoc 615
1/n 0.875
Notes and range EU dossier Kf range 1.14-5.76 mL/g, Kfoc range 393-870 mL/g, 1/n range 0.833-0.914, Soils=6
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
thiacloprid-amide This metabolite may cause environmental pollution, click here for further information Soil   0.740   Major fraction, Relevant
thiacloprid sulfonic acid This metabolite may cause environmental pollution, click here for further information Soil   0.200   Major fraction, Relevant


ECOTOXICOLOGY

for thiacloprid

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) 444 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) > 7.3 A5 Rat High
(ppm diet) > 100 -
Birds - Acute LD50 (mg kg-1) 49 A5 Coturnix japonica High
Birds - Short term dietary (LC50/LD50) > 2250 mg kg feed-1 A5 Coturnix japonica -
Fish - Acute 96 hour LC50 (mg l-1) 24.5 F4 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 85.1 C4 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.58 P3 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 95.4 C4 Lemna gibba Low
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 60.6 C4 Raphidocelis subcapitata Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 38.82 A5 Moderate
Oral acute 48 hour LD50 (μg bee-1) 17.32 A5 Moderate
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 105 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 62.5 A5 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 6.8 as LC50
A5 Aphidius rhopalosiphi
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect 30
30
Mortality
Beneficial capacity
Dose: 0.4 kg ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 2.57 mg kg-1 soil, 28 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for thiacloprid

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 444 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 0.481 F4 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.01 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.03 A5 Rat, SF=100 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.02 A3 Rabbit, SF=100 -
Dermal penetration studies (%) 1.0-10.0 A5 concentration dependant -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Minimal risk from dietary exposure
Risk assessment indicates ARfD would not normally be execeeded
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

-

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Possible liver and thyroid toxicant
USEPA - probable human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive
IMDG Transport Code is usually 6.1
CLP classification 2013 None allocated at this time
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R20/22
N - Dangerous for the environment: R52/53
EC Safety Classification Click here to view information omn the EU safety phrases S60
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Variable with product, usually 2902 or 3077
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for thiacloprid

Language Name
English thiacloprid
French thiacloprid
German Thiacloprid
Danish thiacloprid
Italian tiacloprid
Spanish tiacloprid
Greek -
Slovenian tiakloprid
Polish tiachlopryd
Swedish tiakloprid
Hungarian tiakloprid
Dutch thiacloprid

Record last updated: Monday 07 August 2017
Contact: aeru@herts.ac.uk
© University of Hertfordshire