| 4-(4-chlorophenyl)-2-(methyl-1H-1,2,4-triazole)-4-oxo-2-phenylbutanenitrile (Ref: RH-6467) |
|
Environmental Fate - Ecotoxicology - Human Health
GENERAL INFORMATION 
Description: Chemical transformation product
Introduction: Not applicable
EC Directive 1107/2009 (repealing 91/414):
| Status | Not applicable |
| Dossier rapporteur/co-rapporteur | Not applicable |
| Date inclusion expires | Not applicable |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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General status:
| Pesticide type | Metabolite | |||
| Metabolite Type | Soil | |||
| Substance group | Ketone | |||
| Substance origin | Synthetic | |||
| Mode of action | Not applicable | |||
| CAS RN | - | |||
| EC number | - | |||
| CIPAC number | - | |||
| US EPA chemical code | Not applicable | |||
| Chemical formula | - | |||
| SMILES | - | |||
| International Chemical Identifier (InChI) | - | |||
| Structure diagram/image available? | No | |||
| Molecular mass (g mol-1) | 350.8 | |||
| Chemical name | 4-(4-chlorophenyl)-4-oxo-2-phenyl-2-(1H-1,2,4-triazole-1-ylmethyl)butanenitrile | |||
| Other status information | - | |||
| Herbicide Resistance Classification (HRAC) | Not applicable | |||
| Insecticide Resistance Classification (IRAC) | Not applicable | |||
| Fungicide Resistance Classification (FRAC) | Not applicable | |||
| Physical state | - | |||
| Related substances & organisms | - | |||
Can be a metabolite of:
| Parent | Formation Medium | Estimated Maximum Occurrence Fraction | 91/414 Relevancy |
|
| fenbuconazole | Soil | 0.056 | Minor fraction, Relevant | |
Formulations:
| Property |
Value | |||
| Example manufacturers of products using this active |
|
|||
| Example products using this active | - | |||
| UK LERAP status | Not applicable | |||
| Formulation and application details | - | |||
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | - | - | - | |
| Solubility - In organic solvents at 20oC (mg l-1) | - | - | - | |
| Melting Point (oC) | - | - | - | |
| Boiling Point (oC) | - | - | - | |
| Degradation point (oC) | - | - | - | |
| Flashpoint (oC) | - | - | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | - | - | - |
| Log P | - | - | - | |
| Bulk density (g ml-1)/Specific gravity | - | - | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 25oC (mPa) | - | - | - | |
| Henry's law constant at 25oC (Pa m3 mol-1) | - | - | - | |
| Henry's law constant at 20oC (dimensionless) | - | - | - | |
GUS leaching potential index  |
2.12 | Calculated | Transition state | |
| SCI-GROW groundwater index (µg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 9.91 X 10-02 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | High | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Soil degradation (days) (aerobic) | DT50 (typical) | 244 | A5 | Persistent |
| DT50 (lab at 20oC) | 157.2 | A5 | Persistent | |
| DT50 (field) | - | - | - | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| Note | EU dossier lab studies DT50 range 93.8-286.4 | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | - | - | - |
| Note | - | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | - | - | - |
| Note | - | |||
| Water-Sediment DT50 (days) | - | - | - | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | - | - |
| Koc | - | |||
| Notes and range | - | |||
| Freundlich | Kf | 17 | A5 | Slightly mobile |
| Kfoc | 1293 | |||
| 1/n | 0.92 | |||
| Notes and range | EU dossier Kf range 12-30 mL/g, Kfoc range 938-1500 mL/g, 1/n range 0.9-0.93, Soils=4 | |||
| pH sensitivity | No | |||
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF | - | - | - |
| CT50 (days) | - | - | ||
| Bioaccumulation potential | - | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | - | - | - | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | - | - |
| (ppm diet) | - | - | ||
| Birds - Acute LD50 (mg kg-1) | - | - | - | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | - | - | - | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Algae - Acute 72 hour EC50, growth (mg l-1) | - | - | - | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | - | - | - | |
| Honeybees - Acute 48 hour LD50 (µg bee-1) | - | - | - | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | - | - | - | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50product ha EC50product ha NOECproduct ha % Effect |
- | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Mammals - Acute oral LD50 (mg kg-1) | - | - | - | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | - | - | - | |
| Mammals - Inhalation LC50 (mg l-1) | - | - | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | - | - | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | - | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | - | |||
| Examples of European MRLs (mg kg-1) | Value | - | ||
| Note | For the EU pesticides database click here | |||
| Drinking Water MAC (µg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Acetyl cholinesterase inhibitor | Neurotoxicant | Respiratory tract irritant | Skin irritant | Eye irritant |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| General human health issues | [No further information available] | |||||||
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
||||
| General |
[No information available] | ||||||
| EC Risk Classification |
- | ||||||
| EC Safety Classification |
- | ||||||
| WHO Classification | NL | - | Not listed | ||||
| US EPA Classification (formulation) | Not applicable | - | - | ||||
| UN Number | - | ||||||
| Waste disposal & packaging |
- | ||||||
| Language | Name |
| English | 4-(4-chlorophenyl)-2-(methyl-1H-1,2,4-triazole)-4-oxo-2-phenylbutanenitrile |
| French | - |
| German | - |
| Danish | - |
| Italian | - |
| Spanish | - |
| Greek | - |
| Slovenian | 4-(4-klorofenil)-2-(metil-1H-1,2,4-triazol)-4-okso-2-fenilbutanenitril |
| Polish | 4-(4-chlorofenylo)-2-(metylo-1H-1,2,4-triazolo)-4-okso-2-fenylobutanonitryl |
| Swedish | - |
| Hungarian | - |
| Dutch | - |
| Record last updated: Wednesday 04 January 2012 Contact: aeru@herts.ac.uk |
