| butylate (Ref: R 1910) |
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Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
GENERAL INFORMATION 
for butylate
Description: A herbicide used to control annual grass weeds and some broad-leaved weeds
Example pests controlled: Nutgrass; Millet; Purple nutsedge; Johnsongrass: Quackgrass
Example applications: Sweetcorn; Field corn; Popcorn
Efficacy & activity: -
Availability status: Current
Introduction & key dates: circa 1962
EC Regulation 1107/2009 (repealing 91/414):
| Status | Not approved |
| Dossier rapporteur/co-rapporteur | - |
| Date inclusion expires | Expired |
| EU Candidate for substitution (CfS) | - |
| Listed in EU database | Yes |
Approved for use (
) or known to be used (
) in the following European countries: 
AT |
BE |
BG |
CY |
CZ |
DE |
DK |
EE |
EL |
ES |
FI |
FR |
HR |
HU |
IE |
IT |
LT |
LU |
LV |
MT |
NL |
PL |
PT |
RO |
SE |
SI |
SK |
UK |
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Also used in: USA
Chemical structure:
| Isomerism | - |
| Chemical formula | C11H23NOS |
| Canonical SMILES | CCSC(=O)N(CC(C)C)CC(C)C |
| Isomeric SMILES | No data |
| International Chemical Identifier key (InChIKey) | BMTAFVWTTFSTOG-UHFFFAOYSA-N |
| International Chemical Identifier (InChI) | InChI=1S/C11H23NOS/c1-6-14-11(13)12(7-9(2)3)8-10(4)5/h9-10H,6-8H2,1-5H3 |
| Structure diagram/image available? | Yes |
General status:
| Pesticide type | Herbicide | |||
| Substance group | Thiocarbamate | |||
| Minimum active substance purity | - | |||
| Known relevant impurities | - | |||
| Substance origin | Synthetic | |||
| Mode of action | Selective, systemic absorbed by roots and coleoptiles. Lipid synthesis inhibitor. | |||
| CAS RN | 2008-41-5 | |||
| EC number | 217-916-3 | |||
| CIPAC number | 266 | |||
| US EPA chemical code | 041405 | |||
| PubChem CID | 16181 | |||
| Molecular mass (g mol-1) | 217.4 | |||
| PIN (Preferred Identification Name) | S-ethyl bis(2-methylpropyl)carbamothioate | |||
| IUPAC name | S-ethyl diisobutyl(thiocarbamate) | |||
| CAS name | S-ethyl bis(2-methylpropyl)carbamothioate | |||
| Other status information | Potential groundwater contaminant | |||
| Relevant Environmental Water Quality Standards | - | |||
| Herbicide Resistance Classification (HRAC) | N | |||
| Herbicide Resistance Classification (WSSA) | 8 | |||
| Insecticide Resistance Classification (IRAC) | Not applicable | |||
| Fungicide Resistance Classification (FRAC) | Not applicable | |||
| Examples of recorded resistance | - | |||
| Physical state | Yellow liquid | |||
| Related substances & organisms | - | |||
Formulations:
| Property |
Value | |||
| Example manufacturers & suppliers of products using this active now or historically |
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| Example products using this active |
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| UK LERAP status | No UK approval for use as a pesticide under EC Regulation 1107/2009 | |||
| Formulation and application details | Supplied as an emulsifiable concentrate or as granules. | |||
ENVIRONMENTAL FATE
for butylate
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Solubility - In water at 20oC (mg l-1) | 45 | G4 | Low | |
| Solubility - In organic solvents at 20oC (mg l-1) | Miscible | L3 - Acetone | - | |
| Miscible | L3 - Xylene | - | ||
| Miscible | L3 - Ethanol | - | ||
| Miscible | L3 - Kerosene | - | ||
| Melting point (oC) | 137.7 | L3 | - | |
| Boiling point (oC) | 138 | L3 | - | |
| Degradation point (oC) | 200 | L3 | - | |
| Flashpoint (oC) | 115 | L3 | - | |
| Octanol-water partition coefficient at pH 7, 20oC | P | 1.26 X 1004 | Calculated | - |
| Log P | 4.1 | G4 | High | |
| Bulk density (g ml-1)/Specific gravity | 0.94 | L3 | - | |
| Dissociation constant (pKa) at 25oC | - | - | - | |
| Note: | ||||
| Vapour pressure at 20oC (mPa) | 170 | G4 | Highly volatile | |
| Henry's law constant at 25oC (Pa m3 mol-1) | 1.04 X 1001 | L3 | Moderately volatile | |
GUS leaching potential index  |
2.24 | Calculated | Transition state | |
| SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate |
Value | 1.05 X 10-01 | Calculated | - |
| Note | - | |||
| Potential for particle bound transport index |
- | Calculated | Low | |
| Maximum UV-vis absorption L mol-1 cm-1 | - | - | - | |
| Surface tension (mN m-1) | - | - | - | |
Degradation:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
General biodegradability | - |
| Soil degradation (days) (aerobic) | DT50 (typical) | 40 | L3 | Moderately persistent |
| DT50 (lab at 20oC) | - | - | - | |
| DT50 (field) | 13 | Q3 | Non-persistent | |
| DT90 (lab at 20oC) | - | - | - | |
| DT90 (field) | - | - | - | |
| DT50 modelling endpoint | - | - | - | |
| Note | Other sources: DT50 10-70 days (Q3, L3); DT50 = 24 days sandy soil (F3) | |||
| Dissipation rate RL50 on plant matrix | Value | - | - | - |
| Note | - | |||
| Dissipation rate RL50 on and in plant matrix | Value | - | - | - |
| Note | - | |||
| Aqueous photolysis DT50 (days) at pH 7 | Value | - | L3 | - |
| Note | Degrades in UV light | |||
| Aqueous hydrolysis DT50 (days) at 20oC and pH 7 | Value | Stable | L3 | - |
| Note | Stable under most environmental conditions but hydrolysed by strong acids and alkalis | |||
| Water-sediment DT50 (days) | - | - | - | |
| Water phase only DT50 (days) | - | - | - | |
Soil adsorption and mobility:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Linear | Kd | - | G3 | Moderately mobile |
| Koc | 400 | |||
| Notes and range | - | |||
| Freundlich | Kf | - | - | - |
| Kfoc | - | |||
| 1/n | - | |||
| Notes and range | - | |||
| pH sensitivity | - | |||
Key metabolites:
| Metabolite | Formation medium | Estimated maximum occurrence fraction | 1107/2009 relevancy |
|
| ethanethiol | Soil | - | - | |
| diisobutylamine | Soil | - | - | |
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Bio-concentration factor | BCF (l kg-1) | 410 | F4 Whole fish | Threshold for concern |
| CT50 (days) | Not available | - | ||
| Mammals - Acute oral LD50 (mg kg-1) | 3500 | L3 Rat | Low | |
| Mammals - Short term dietary NOEL | (mg kg-1) | - | L3 Rat | - |
| (ppm diet) | 32 | - | ||
| Birds - Acute LD50 (mg kg-1) | > 4640 | G4 Anas platyrhynchos | Low | |
| Birds - Short term dietary (LC50/LD50) | - | - | - | |
| Fish - Acute 96 hour LC50 (mg l-1) | > 4.2 | G4 Oncorhynchus mykiss | Moderate | |
| Fish - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) | > 158.6 | F4 Daphnia magna | Low | |
| Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) | - | - | - | |
| Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) | - | - | - | |
| Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) | - | - | - | |
| Aquatic plants - Acute 7 day EC50, biomass (mg l-1) | - | - | - | |
| Non-target plants | - | - | - | |
| - | - | - | ||
| Algae - Acute 72 hour EC50, growth (mg l-1) | 0.5 | F4 Pseudokirchneriella subcapitata | Moderate | |
| Algae - Chronic 96 hour NOEC, growth (mg l-1) | 0.17 | J3 Green algae, LOEC | Moderate | |
| Honeybees | Contact acute 48 hour LD50 (μg bee-1) | - | - | - |
| Oral acute 48 hour LD50 (μg bee-1) | - | - | - | |
| Unknown mode acute 48 hour LD50 (μg bee-1) | > 29.0 | F4 | Moderate | |
| Earthworms - Acute 14 day LC50 (mg kg-1) | - | - | - | |
| Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) | - | - | - | |
| Other soil macro-organisms - e.g. Collembola | LR50 / EC50 / NOEC / % Effect | - | - | - |
| Other arthropod (1) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Other arthropod (2) | LR50 g ha-1 | - | - | - |
| % Effect | - | - | - | |
| Soil micro-organisms | - | - | - | |
| Mesocosm study data | NOEAEC mg l-1 | - | - | - |
| NOEAEC mg l-1 | - | - | - | |
HUMAN HEALTH AND PROTECTION
for butylate
General:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| Threshold of Toxicological Concern (Cramer Class) |
High (class III) | - | - | |
| Mammals - Acute oral LD50 (mg kg-1) | 3500 | L3 Rat | Low | |
| Mammals - Dermal LD50 (mg kg-1 body weight) | > 5000 | L3 Rabbit | - | |
| Mammals - Inhalation LC50 (mg l-1) | 5.2 | L3 Rat | - | |
| Other Mammal toxicity endpoints | - | - | ||
| ADI - Acceptable Daily Intake (mg kg-1bw day-1) | - | - | - | |
| ARfD - Acute Reference Dose (mg kg-1bw day-1) | - | - | - | |
| AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) | - | - | - | |
| AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) | - | - | - | |
| Dermal penetration studies (%) | - | - | - | |
| Dangerous Substances Directive 76/464 | - | - | - | |
| Exposure Limits | - | - | - | |
| Exposure Routes | Public | - | ||
| Occupational | The major routes of exposure to butylate are through the skin and by inhalation | |||
| European MRLs | Click here for the EU MRL pesticide database | |||
| Drinking Water Standards | - | - | - | |
| Drinking Water MAC (μg l-1) | - | - | - | |
Health issues:
| Carcinogen | Mutagen | Endocrine disrupter | Reproduction / development effects | Cholinesterase inhibitor | Neurotoxicant | |||
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| Respiratory tract irritant | Skin irritant | Skin sensitiser | Eye irritant | Phototoxicant | ||||
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| General human health issues | No further information available | |||||||
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found
Handling issues:
| Property |
Value | Source/Quality Score/Other Information |
Interpretation |
|
| General |
No information available | |||
| CLP classification 2013 | - | |||
| EC Risk Classification |
Xn - Harmful: R20 N - Dangerous for the environment: R51/53 |
|||
| EC Safety Classification |
S60 | |||
| WHO Classification | III | - | Slightly hazardous | |
| US EPA Classification (formulation) | III | - | Caution - Slightly toxic | |
| UN Number | - | |||
| Waste disposal & packaging |
- | |||
| Language | Name |
| English | butylate |
| French | butilate |
| German | Butylat |
| Danish | butylat |
| Italian | butilate |
| Spanish | butilato |
| Greek | - |
| Slovenian | butilat |
| Polish | butylat |
| Swedish | butylat |
| Hungarian | butylate |
| Dutch | - |
Record last updated: Wednesday 23 May 2018
Contact: aeru@herts.ac.uk