2,5-dichlorobenzoic acid methyl ester ** benzoic acid, 2,5-dichloro-, methyl ester ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for 2,5-dichlorobenzoic acid methyl ester

Description: Used in the formulation of grafting waxes used to induce callus formation of grapevine cuttings

Introduction: Not applicable

EC Regulation 1107/2009 (repealing 91/414):

Status	Approved
Dossier rapporteur/co-rapporteur	Germany
Date inclusion expires	31/08/2019

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:

Pesticide type	Plant growth regulator, Fungicide
Substance group	Benzoic acid
Substance origin	Synthetic
Mode of action	Topical
CAS RN	2905-69-3
EC number	220-815-7
CIPAC number	686
US EPA chemical code	-
Chiral molecule	No
Chemical formula	C8H6O2Cl2
SMILES	O=C(OC)c1cc(Cl)ccc1Cl
International Chemical Identifier (InChI)	InChI=1/C8H6Cl2O2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,1H3
Structure diagram/image available?	Yes
Molecular mass (g mol-1)	205.04
IUPAC name	methyl-2,5-dichlorobenzoate
CAS name	methyl-2,5-dichlorobenzoate
Other status information	-
Herbicide Resistance Classification (HRAC)	Not applicable
Insecticide Resistance Classification (IRAC)	Not applicable
Fungicide Resistance Classification (FRAC)	Not known
Physical state	Pale yellow crystals
Related substances & organisms	-

Formulations:

Property	Value
Example manufacturers of products using this active	Stahler International GmbH
Example products using this active	Rebwachs WF
UK LERAP status	No UK approval for use or outside scope
Formulation and application details	Often supplied as a waxy solid for use when grafting.

ENVIRONMENTAL FATE
for 2,5-dichlorobenzoic acid methyl ester

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		87.0	A5	Moderate
Solubility - In organic solvents at 20oC (mg l-1)		1000000	A5 - Dichloromethane	-
		1000000	A5 - Ethyl acetate	-
		1000000	A5 - Xylene	-
		800000	A5 - Methanol	-
Melting point (oC)		38.7	A5	-
Boiling point (oC)		250.6	A5	-
Degradation point (oC)		440	A5	-
Flashpoint (oC)		Not expected to self ignite; Not highly flammable	A5	-
Octanol-water partition coefficient at pH 7, 20oC	P	2.88 X 1003	Calculated	-
	Log P	3.46	A5	High
Bulk density (g ml-1)/Specific gravity		1.36	Q2	-
Dissociation constant (pKa) at 25oC		Not applicable	A5	-
		Note: No dissociation
Vapour pressure at 25oC (mPa)		320000	A5	Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1)		1.63	A5	Moderately volatile
Henry's law constant at 20oC (dimensionless)		3.10 X 10-01	Calculated	Volatile
GUS leaching potential index		-	-	-
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate	Value	-	-	-
	Note	-
Potential for particle bound transport index		-	-	-
Maximum UV-vis absorption L mol-1 cm-1		203nm = 37769, 229nm = 11852, 276nm = 7730, 292nm = ~6000, 334nm = ~10	A5	-
Surface tension (mN m-1)		60	A5 at 20oC	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
Soil degradation (days) (aerobic)	DT50 (typical)	-	-	-
	DT50 (lab at 20oC)	-	-	-
	DT50 (field)	-	-	-
	DT90 (lab at 20oC)	-	-	-
	DT90 (field)	-	-	-
	Note:	-
Aqueous photolysis DT50 (days) at pH 7	Value	-	-	-
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	-	-	-
	Note	-
Water-Sediment DT50 (days)		-	-	-
Water phase only DT50 (days)		-	-	-

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	Q2	Slightly mobile
	Koc	1105
	Notes and range	Estimated
Freundlich	Kf	-	-	-
	Kfoc	-
	1/n	-
	Notes and range	-
pH sensitivity		-

Other known metabolites:

Metabolite name and reference	Aliases	Formation medium / Rate	Estimated maximum occurrence fraction	Metabolising enzymes
2,5-dichlorobenzoic acid	M11.7	Rat (Urinary); Animal	-	-
2,5-dichlorobenzoylglycine	M7.2	Rat (Urinary); Animal	-	-
5-hydroxy-3,6-dichloro-o-anisic acid	-	Plant	-	-

ECOTOXICOLOGY
for 2,5-dichlorobenzoic acid methyl ester

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF	-	-	-
	CT50 (days)	-		-
Bioaccumulation potential		-	-	-
Mammals - Acute oral LD50 (mg kg-1)		1030	A5 Rat	Moderate
Mammals - Short term dietary NOEL	(mg kg-1)	-	-	-
	(ppm diet)	-		-
Birds - Acute LD50 (mg kg-1)		-	-	-
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		14.4	F4 Pimephales promelas	Moderate
Fish - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		-	-	-
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		-	-	-
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees - Acute 48 hour LD50 (μg bee-1)		-	-	-
Earthworms - Acute 14 day LC50 (mg kg-1)		-	-	-
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		-	-	-
Other soil macro-organisms - e.g. Collembola	LR50 / EC50 / NOEC / % Effect	-	-	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		-	-	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION
for 2,5-dichlorobenzoic acid methyl ester

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Mammals - Acute oral LD50 (mg kg-1)		1030	A5 Rat	Moderate
Mammals - Dermal LD50 (mg kg-1 body weight)		> 10000	A5 Rat	-
Mammals - Inhalation LC50 (mg l-1)		-	-	-
Other Mammal toxicity endpoints		-		-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		None allocated	A5	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		None allocated	A5	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		0.1	A5 Rat, SF=1000	-
Dermal penetration studies (%)		100	A3 default	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	Negligible risk to bystanders
	Occupational	Negligible risks of exposure to operators and workers
Examples of European MRLs (mg kg-1)	Value	-
	Note	For the EU pesticides database click here
Drinking Water MAC (μg l-1)		-	-	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Acetyl cholinesterase inhibitor	Neurotoxicant	Respiratory tract irritant	Skin irritant	Eye irritant
-	-	-	-	-	-	-
General human health issues		May cause anaemia Possible liver and kidney toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		Not explosive or oxidising
CLP classification 2013		-
EC Risk Classification		Xn - Harmful: R22 Xi - Irritant: R36
EC Safety Classification		-
WHO Classification		NL	-	Not listed
US EPA Classification (formulation)		Not applicable	-	-
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS
for 2,5-dichlorobenzoic acid methyl ester