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metofluthrin (Ref: S 1264)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for metofluthrin

Description: Mainly used as a mosquito repellent impregnated on to paper strips and positioned in outdoor areas such as gardens, campsites and patios

Introduction: 2004, Japan

EC Regulation 1107/2009 (repealing 91/414):
Status Not listed
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires -

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Insecticide, Repellent
Substance group Pyrethroid ester
Substance origin Synthetic
Mode of action Vapour active, knock-down action. Sodium channel modulator.
CAS RN 240494-70-6
EC number -
CIPAC number None allocated
US EPA chemical code 109709
Chiral molecule Chiral or specific isomer of chiral molecule
Chemical formula C18H20F4O3
SMILES Fc1c(F)c(c(F)c(F)c1COC(=O)C2C(/C=C/C)C2(C)C)COC
International Chemical Identifier (InChI) InChI=1/C18H20F4O3/c1-5-6-11-12(18(11,2)3)17(23)25-8-10-15(21)13(19)9(7-24-4)14(20)16(10)22/h5-6,11-12H,7-8H2,1-4H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 360.34
PIN (Preferred Identification Name) [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1E,3E)-2,2-dimethyl-3-[(1E)-prop-1-en-1-yl]cyclopropane-1-carboxylate
IUPAC name 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (EZ)-(1RS,3RS;1RS,3SR)-2,2-dimethyl-3-prop-1-enylcyclopropanecarboxylate
CAS name [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate
Other status information -
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Physical state Pale yellow liquid
Related substances & organisms -

Formulations:
Property Value
Example manufacturers & suppliers of products using this active -
Example products using this active -
UK LERAP status No UK approval for use or outside scope
Formulation and application details -


ENVIRONMENTAL FATE

for metofluthrin

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 0.67 F3 Low
Solubility - In organic solvents at 20oC (mg l-1) 303400 F3 - Acetone -
312200 F3 - Methanol -
307600 F3 - Ethyl acetate -
326900 F3 - Toluene -
Melting point (oC) -54 F3 -
Boiling point (oC) 334 L3 -
Degradation point (oC) - - -
Flashpoint (oC) 110 L3 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 1.07 X 1005 Calculated -
Log P 5.03 F3 High
Bulk density (g ml-1)/Specific gravity 1.21 F3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 1.8 R4 - 25DegC Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1) - - -
Henry's law constant at 20oC (dimensionless) 3.97 X 10-04 Calculated Volatile
GUS leaching potential index 0.19 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 2.67 X 10-03 Calculated -
Note -
Potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 4.5 F3 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Aerobic DT50 1-8 days sandy loam
Aqueous photolysis DT50 (days) at pH 7 Value 6.0 F2 Moderately fast
Note DT50 6 days at pH 4
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable F3 Very persistent
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - P4 Non-mobile
Koc 5199
Notes and range Koc range 4489-7187 mL/g
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for metofluthrin

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF - - -
CT50 (days) - -
Bioaccumulation potential - - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 F3 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 2250 F3 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 1.2 F3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.00071 F3 Oncorhynchus mykiss -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0047 F3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.003 F3 Daphnia magna -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for metofluthrin

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) > 2000 F3 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 F3 Rat -
Mammals - Inhalation LC50 (mg l-1) 1.08 F3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

General human health issues Liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General No information available
CLP classification 2013 -
EC Risk Classification Xi - Irritant: R36
EC Safety Classification -
WHO Classification NL - Not listed
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for metofluthrin

Language Name
English metofluthrin
French -
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian -
Polish -
Swedish -
Hungarian -
Dutch -

Record last updated: Thursday 31 July 2014
Contact: aeru@herts.ac.uk