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metofluthrin (Ref: S 1264)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for metofluthrin

Description: Mainly used as a mosquito repellent impregnated on to paper strips and positioned in outdoor areas such as gardens, campsites and patios

Introduction: 2004, Japan

EC Regulation 1107/2009 (repealing 91/414):
Status Not listed
Dossier rapporteur/co-rapporteur Not applicable
Date inclusion expires -

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Insecticide, Repellent
Substance group Pyrethroid ester
Substance origin Synthetic
Mode of action Vapour active, knock-down action. Sodium channel modulator.
CAS RN 240494-70-6
EC number -
CIPAC number None allocated
US EPA chemical code 109709
Chiral molecule Chiral, a specific isomer or a derivative of a chiral molecule
Chemical formula C18H20F4O3
SMILES Fc1c(F)c(c(F)c(F)c1COC(=O)C2C(/C=C/C)C2(C)C)COC
International Chemical Identifier key (InChIKey) -
International Chemical Identifier (InChI) InChI=1/C18H20F4O3/c1-5-6-11-12(18(11,2)3)17(23)25-8-10-15(21)13(19)9(7-24-4)14(20)16(10)22/h5-6,11-12H,7-8H2,1-4H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 360.34
PIN (Preferred Identification Name) [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1E,3E)-2,2-dimethyl-3-[(1E)-prop-1-en-1-yl]cyclopropane-1-carboxylate
IUPAC name 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (EZ)-(1RS,3RS;1RS,3SR)-2,2-dimethyl-3-prop-1-enylcyclopropanecarboxylate
CAS name [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate
Other status information -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Physical state Pale yellow liquid
Related substances & organisms -

Formulations:
Property Value
Example manufacturers & suppliers of products using this active -
Example products using this active -
UK LERAP status No UK approval for use or outside scope
Formulation and application details -


ENVIRONMENTAL FATE

for metofluthrin

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 0.67 F3 Low
Solubility - In organic solvents at 20oC (mg l-1) 303400 F3 - Acetone -
312200 F3 - Methanol -
307600 F3 - Ethyl acetate -
326900 F3 - Toluene -
Melting point (oC) -54 F3 -
Boiling point (oC) 334 L3 -
Degradation point (oC) - - -
Flashpoint (oC) 110 L3 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 1.07 X 1005 Calculated -
Log P 5.03 F3 High
Bulk density (g ml-1)/Specific gravity 1.21 F3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 1.8 R4 - 25DegC Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1) - - -
Henry's law constant at 20oC (dimensionless) 3.97 X 10-04 Calculated Volatile
GUS leaching potential index 0.19 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 2.67 X 10-03 Calculated -
Note -
Potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 4.5 F3 Non-persistent
DT50 (lab at 20oC) - - -
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Aerobic DT50 1-8 days sandy loam
Aqueous photolysis DT50 (days) at pH 7 Value 6.0 F2 Moderately fast
Note DT50 6 days at pH 4
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable F3 Very persistent
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - P4 Non-mobile
Koc 5199
Notes and range Koc range 4489-7187 mL/g
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for metofluthrin

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF - - -
CT50 (days) - -
Bioaccumulation potential - - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 F3 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 2250 F3 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 1.2 F3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.00071 F3 Oncorhynchus mykiss -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0047 F3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.003 F3 Daphnia magna -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) - - -
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for metofluthrin

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) > 2000 F3 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 F3 Rat -
Mammals - Inhalation LC50 (mg l-1) 1.08 F3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

General human health issues Liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General No information available
CLP classification 2013 -
EC Risk Classification Xi - Irritant: R36
EC Safety Classification -
WHO Classification NL - Not listed
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number -
Waste disposal & packaging -


TRANSLATIONS

for metofluthrin

Language Name
English metofluthrin
French -
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian -
Polish -
Swedish -
Hungarian -
Dutch -

Record last updated: Thursday 31 July 2014
Contact: aeru@herts.ac.uk