Fenthion (Ref: OMS 2) |
![]() Last updated: 21/01/2021 |
![]() |
(Also known as: MPP; ENT 25540; Bayer 29493; S-1752; BAY 29493; DMTP) |
SUMMARY |
Fenthino is an insecticide that is no longer approved for use in the EU. It has a low water solubility but is generally highly soluble in organic solvents. It is volatile and is not expected to leach to groundwater. Its persistence in soil and water systems depends on local conditions. It is moderately toxic to mammals and a cholinesterase inhibitor. Fenthion is highly toxic to birds and honeybees and has a high to moderate toxicity to most aquatic species and earthworms. |
|
![]() |
|
A broad spectrum insecticide used to control various sucking and biting insect pests in a range of agricultural, commercial and domestic situations. It is also used in veterinary medicine and for bird control | |
---|---|---|
|
Fruit flies, Leafhoppers, Leaf miners, Stem borers, Codling moth, Mosquitoes, Pigeons, Weaver birds | |
|
Fruit including apples, pears, avocadoes, grapes, stone fruit; Peppers; Ornamental trees, flowers and shrubs | |
|
- | |
|
Current | |
|
1960, first reported & introduced |
UK regulatory status |
|
Not approved | ||
---|---|---|---|
|
Expired | ||
|
No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
|
Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Greece | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
- | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
Also used in |
|
- |
---|
Chemical structure |
|
- | |
---|---|---|
|
C₁₀H₁₅O₃PS₂ | |
|
CC1=C(C=CC(=C1)OP(=S)(OC)OC)SC | |
|
No data | |
|
PNVJTZOFSHSLTO-UHFFFAOYSA-N | |
|
InChI=1S/C10H15O3PS2/c1-8-7-9(5-6-10(8)16-4)13-14(15,11-2)12-3/h5-7H,1-4H3 | |
|
Yes |
General status |
|
Insecticide, Veterinary substance, Avicide | |
---|---|---|
|
Organophosphate | |
|
- | |
|
- | |
|
Synthetic | |
|
Contact, stomach and respiratory action. Cholinesterase inhibitor. | |
|
55-38-9 | |
|
200-231-9 | |
|
79 | |
|
053301 | |
|
3346 | |
|
278.33 | |
|
O,O-dimethyl O-[3-methyl-4-(methylsulfanyl)phenyl] phosphorothioate | |
|
O,O-dimethyl O-4-methylthio-m-tolyl phosphorothioate | |
|
O,O-dimethyl O-(3-methyl-4-(methylthio)phenyl) phosphorothioate | |
|
Severe Marine Pollutant; Evidence of use in third world countries; Chemical subject to PIC regulations; Highly toxic to birds | |
|
- | |
|
Not applicable | |
|
Not applicable | |
|
1B | |
|
Not applicable | |
|
Many recorded cases, mosquitoes, Bactrocera dorsalis, Myzus persicae, Panonychus ulmi, Rhizoglyphus robini | |
|
Colourless oily liquid |
Formulations |
|
|
|||
---|---|---|---|---|
|
|
|||
|
|
|||
|
Available in a wide range of formulations including dustable powders, emulsifiable concentrates, granules, concentrates, ULV liquids and wettable powders. |
|
![]() |
|
|
|
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
4.2 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
Low | ||||||||
|
100000 | L3 L = Pesticide manuals and hard copy reference books / other sources Hexane3 = Unverified data of known source |
- | ||||||||
250000 | L3 L = Pesticide manuals and hard copy reference books / other sources Toluene3 = Unverified data of known source |
- | |||||||||
250000 | L3 L = Pesticide manuals and hard copy reference books / other sources Dichloromethane3 = Unverified data of known source |
- | |||||||||
250000 | L3 L = Pesticide manuals and hard copy reference books / other sources Isopropanol3 = Unverified data of known source |
- | |||||||||
|
7.5 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) 4 = Verified data |
- | ||||||||
|
90 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
- | ||||||||
|
- | - | - | ||||||||
|
170 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
- | ||||||||
|
|
6.92 X 1004 | Calculated | - | |||||||
|
4.84 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
High | ||||||||
|
1.25 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) 4 = Verified data |
- | ||||||||
|
- | - | - | ||||||||
- | |||||||||||
|
0.37 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
Low volatility | ||||||||
|
2.40 X 10-02 | H4 H = The US ARS pesticide properties database (click here ) 4 = Verified data |
Non-volatile | ||||||||
|
- | - | - | ||||||||
|
- | - | - |
Degradation |
|
|
|
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
- | ||||||||||
|
|
22 | W4 W = French database provided by ARVALIS-Institut du Végétal 4 = Verified data |
Non-persistent | |||||||
|
34 | DW4 DW = Don Wauchope personal database for Pka data: Wauchope, R. D. and Edwards, J. Dissociation constants for pesticide active ingredients: a database and comparison with predicted values. MS in preparation 4 = Verified data |
Moderately persistent | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
Data variable DT₅₀ ranges 1(aerobic) - 34 days | ||||||||||
|
|
6.6 | R4 R = Peer reviewed scientific publications 4 = Verified data |
- | |||||||
|
Published literature RL₅₀ range 5.6-7.6 days, grape berries, n=2; Grape berries in cold storage RL₅₀ range 42-45 days, n=2 | ||||||||||
|
|
4.4 | R4 R = Peer reviewed scientific publications 4 = Verified data |
- | |||||||
|
Published literature RL₅₀ range 1.0-8.0 days, 6 field crops, various matrices, n=12 | ||||||||||
|
|
0.4 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) 4 = Verified data |
Fast | |||||||
|
- | ||||||||||
|
|
Stable | W4 W = French database provided by ARVALIS-Institut du Végétal 4 = Verified data |
Stable | |||||||
|
- | ||||||||||
|
92 | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
Moderately fast | ||||||||
|
- | - | - |
Soil adsorption and mobility |
|
|
|
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
|
- | G3 G = Extension Toxicology network database EXTOXNET (click here ) 3 = Unverified data of known source |
Slightly mobile | |||||||
|
1500 | ||||||||||
|
- | ||||||||||
|
|
- | - | - | |||||||
|
- | ||||||||||
|
- | ||||||||||
|
- | ||||||||||
|
- |
Fate indices |
|
|
|
|
||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
1.26 | Calculated | Low leachability | ||||||||||||||||||||||||||
|
|
2.77 X 10-02 | Calculated | - | |||||||||||||||||||||||||
|
- | ||||||||||||||||||||||||||||
|
Medium | Calculated | - | ||||||||||||||||||||||||||
|
Slightly mobile | Calculated | - |
Key metabolites |
|
|
|
|
|||||
---|---|---|---|---|---|---|---|---|
|
Soil | - | - | |||||
|
Soil | - | - |
|
![]() |
|
|
|
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
|
154 | R3 R = Peer reviewed scientific publications (Whole body Other literature Log BCF range 1.0-2.3 (3 = Unverified data of known source R3 R = Peer reviewed scientific publications ))3 = Unverified data of known source |
Threshold for concern | |||||||
|
5 | - | |||||||||
|
~ 250 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) Rat4 = Verified data |
Moderate | ||||||||
|
|
- | L2 L = Pesticide manuals and hard copy reference books / other sources Rat 2 year2 = Unverified data of unknown source |
- | |||||||
|
5 | - | |||||||||
|
- | - | - | ||||||||
|
7.2 | E3 E = Manufacturers safety data sheets Colinus virginianus3 = Unverified data of known source |
High | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
0.8 | E3 E = Manufacturers safety data sheets Oncorhynchus mykiss3 = Unverified data of known source |
Moderate | ||||||||
|
0.12 | P3 P = Other governments and regulators Pimephales promelas 30 day3 = Unverified data of known source |
Moderate | ||||||||
|
0.0057 | E3 E = Manufacturers safety data sheets Daphnia magna3 = Unverified data of known source |
High | ||||||||
|
0.000013 | P4 P = Other governments and regulators Daphnia magna4 = Verified data |
High | ||||||||
|
0.00018 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia4 = Verified data |
High | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
- | - | - | |||||||||
|
1.79 | L3 L = Pesticide manuals and hard copy reference books / other sources Scenedemus subspicatus3 = Unverified data of known source |
Moderate | ||||||||
|
> 0.3 | P3 P = Other governments and regulators Pseudokirchneriella subcapitata 48 hr3 = Unverified data of known source |
Moderate | ||||||||
|
|
> 0.308 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
High | |||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
|
- | - | - | |||||||
- | |||||||||||
|
- | - | - | ||||||||
- | |||||||||||
|
|
- | - | - | |||||||
|
- | - | - | ||||||||
|
|
- | - | - | |||||||
|
- | ||||||||||
|
|
- | - | - | |||||||
|
- | ||||||||||
|
375 | E3 E = Manufacturers safety data sheets Eisenia foetida3 = Unverified data of known source |
Moderate | ||||||||
|
- | - | - | ||||||||
|
|
- | - | - | |||||||
|
- | - | - | ||||||||
|
|
- | - | - |
|
- | - | - | |||
|
|
- | - | - |
|
- | - | - | |||
|
Nitrogen mineralisation: >25% effect Carbon mineralisation: No significant adverse effect |
AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) 4 = Verified data Dose: 10 uL/kg soil 20°C |
- | ||||||||
|
|
- | - | - |
|
- | - | - |
|
![]() |
General |
|
|
|
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
High (class III) | - | - | ||||||||
|
~ 250 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) Rat4 = Verified data |
Moderate | ||||||||
|
1680 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) Rat4 = Verified data |
- | ||||||||
|
1.2 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) Rat 4 = Verified data |
- | ||||||||
|
Intraperitoneal LD₅₀ = 260 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
- | ||||||||
Intravenous LD₅₀ = 320 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Mouse3 = Unverified data of known source |
- | |||||||||
|
0.007 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) JMPR 19954 = Verified data |
- | ||||||||
|
0.01 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) JMPR 19974 = Verified data |
- | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
|
List I; List II | - | - | ||||||||
|
|
- | |||||||||
|
Ingestion main poisoning route | ||||||||||
|
|
|
|||||||||
|
- | ||||||||||
|
- | - | - | ||||||||
|
- | - | - |
Health issues |
|
|
||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Harmful in contact with skin or if inhaled or swallowed May harm central nervous, cardiovascular, and respiratory systems |
Handling issues |
|
|
|||
---|---|---|---|---|
|
No information available | |||
|
Health: H302, H312, H331, H341 Environment: H400, H410 |
|||
|
T - Toxic: R23, R48/25, R68 Xn - Harmful: R21/22 N - Dangerous for the environment: R50, R53 |
|||
|
S1/2, S36/37, S45, S60, S61 | |||
|
II (Moderately hazardous) | |||
|
3018 | |||
|
- |
|
![]() |
|
|
||
---|---|---|---|
|
fenthion | ||
|
fenthion | ||
|
Fenthion | ||
|
fenthion | ||
|
fention | ||
|
fention | ||
|
fenthion | ||
|
fention | ||
|
- | ||
|
fention | ||
|
fenthion |
Record last updated: | 21/01/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |