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flurtamone (Ref: RPA 590515)
** SX 1802 ** RE 40885 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Flurtamone is an approved herbicide under EU regulations and used to control broad-leaved weeds and grasses. It has a low aqueous solubility, low volatility and, based on its chemical properties, is not expected to leach to groundwater. It is not normally persistent in soil or water-sediment systems. It has a low mammalian toxicity and no serious health risks have been identified from the literature. It has a low to moderate toxicity to most terrestrial and aquatic species, with the exception of aquatic plants for which toxicity is high.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for flurtamone

Description: A pre-emergence or post-emergence herbicide used pre-planting and soil incorporated to control broad-leaved and some grasses

Example pests controlled: Broad-leaved weeds, Grasses

Example applications: Cereals including barley, wheat, oats, rye; Sunflower; Cotton; Peas

Efficacy & activity: Many products using flurtamone have been in use in the EU more many years with efficiacy proven in the field and under test conditions.

Availability status: Current

Introduction & key dates: circa 1990

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Czech Republic/Ireland
Date inclusion expires 31/10/2019
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism A chiral molecule existing in the R- and S-forms
Chemical formula C18H14F3NO2
Canonical SMILES CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) NYRMIJKDBAQCHC-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Pyridazinone
Minimum active substance purity 982 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Bleaching: inhibition of carotenoid biosynthesis.
CAS RN 96525-23-4
EC number None allocated
CIPAC number 569
US EPA chemical code -
PubChem CID 91755
Molecular mass (g mol-1) 333.30
PIN (Preferred Identification Name) -
IUPAC name (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one
CAS name 5-(methylamino)-2-phenyl-4-[3-(trifluoromethyl)phenyl]-3(2H)-furanone
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) F1
Herbicide Resistance Classification (WSSA) 12
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance -
Physical state Pale yellow powder
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
  • Aventis
  • Rhone-Poulenc
Example products using this active
  • Bacara
  • Graduate
  • Ingot
  • Chevron
  • Dolmen
UK LERAP status None
Formulation and application details Usually supplied as a soluble concentrate applied as an aqueous sloution using standard spraying equipment. at 0.5 L product in 200-400 L water / ha.


ENVIRONMENTAL FATE

for flurtamone

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 10.7 A5 - @pH5 Low
Solubility - In organic solvents at 20oC (mg l-1) 350000 A5 - Acetone -
199000 A5 - Methanol -
18 A5 - Hexane -
133000 A5 - Ethyl acetate -
Melting point (oC) 148.5 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 190 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 1.74 X 1003 Calculated -
Log P 3.24 A5 High
Bulk density (g ml-1)/Specific gravity 1.38 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 7.0 X 10-07 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.03 X 10-08 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 1.64 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 2.74 X 10-02 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 276.2nm=28128; [Acidic solution: 272.6nm=23912; [Basic solution: 215.6nm=17530, 272.6nm=18755 A5 -
Surface tension (mN m-1) 72.1 A5 at 20 degC, 99.1% -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability Not considered to be readily biodegradable
Soil degradation (days) (aerobic) DT50 (typical) 10.7 A5 Non-persistent
DT50 (lab at 20oC) 10.7 A5 Non-persistent
DT50 (field) 35.8 A5 Moderately persistent
DT90 (lab at 20oC) 250 A4 -
DT90 (field) 184 A5 -
DT50 modelling endpoint - - -
Note EU 2017 dossier lab studies DT50 range 9.1-11.7 days, DT90 range 30.2-39.9 days, Soils=4; field studies DT50 range 46-65 days, DT90 range 152-216 days
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 1.0 A5 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 5 to pH 9 at 25 degC
Water-sediment DT50 (days) 82.4 A5 Moderately fast
Water phase only DT50 (days) 16.0 A5 Slow

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf 6.95 A4 Moderately mobile
Kfoc 257.3
1/n 0.876
Notes and range EU 2016 dossier Kf range 4.47-10.62 mL/g, Kfoc range 225-288 mL/g, 1/n range 0.87-0.86, Soils=5
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
trifluoroethanoic acid Soil   0.055   Minor fraction, Relevant
3-trifluoromethylbenzoic acid (Ref: RE-54488) This metabolite may cause environmental pollution, click here for further information Soil   0.247   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
benzoic acid
(Ref: )
Note: Major fraction, Relevant
- Soil - -


ECOTOXICOLOGY

for flurtamone

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 27.5 A5 Whole fish Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) 6.3 B5 Rat High
(ppm diet) 100 -
Birds - Acute LD50 (mg kg-1) > 2530 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 6000 mg kg feed-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 7 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.63 A5 Oncorhynchus mykiss Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 13 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.071 A5 Daphnia magna Moderate
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 0.0099 A5 Lemna gibba High
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.02 A4 Raphidocelis subcapitata, 72 hour Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Low
Oral acute 48 hour LD50 (μg bee-1) > 304 A5 Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 1800 A5 Eisenia foetida Low
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect 33.8 Mortality
Dose: 0.25 kg ha-1
A5 Aphidius rhopalosiphi, adult
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 92.1 Mortality
Dose: 0.25 kg ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: <5% slight stimulation of soil respiration
A3
Dose: Not stated
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for flurtamone

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 5000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 2.2 A5 Rat 4hr (whole body) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.03 A3 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A3 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) 0.19 A3 Rat, SF=300 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.02 A3 Dog, 1 year, SF=100 -
Dermal penetration studies (%) 0.3-8.0% A5 concentration dependent -
Dangerous Substances Directive 76/464 List II - -
Exposure Limits - - -
Exposure Routes Public No unacceptable risks for bystanders identified
Occupational No unacceptable risks to operators or workers identified
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Possible kidney, liver and spleen toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S61, S60
WHO Classification NL - Not listed
US EPA Classification (formulation) No consensus across products or no products available - -
UN Number Usually 3077
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for flurtamone

Language Name
English flurtamone
French flurtamone
German Flurtamone
Danish flurtamon
Italian flurtamone
Spanish flurtamone
Greek flurtamone
Slovenian flurtamon
Polish flurtamon
Swedish flurtamon
Hungarian -
Dutch flurtamone

Record last updated: Monday 05 November 2018
Contact: aeru@herts.ac.uk