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metaldehyde
** acetaldehyde tetramer ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for metaldehyde

Description: A molluscicide bait for controlling slugs and snails

Introduction: 1936, first reported

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Austria
Date inclusion expires 31/05/2021

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also registered in: Australia, USA

General status:
Pesticide type Molluscicide
Substance group Cyclo-octane
Substance origin Synthetic
Mode of action Contact and stomach action
CAS RN 108-62-3
EC number 203-600-2
CIPAC number 62
US EPA chemical code 053001
Chiral molecule No
Chemical formula C8H16O4
SMILES O1C(OC(OC(OC1C)C)C)C
International Chemical Identifier (InChI) InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 176.21
PIN (Preferred Identification Name) -
IUPAC name 2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclooctane
CAS name 2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclooctane
Other status information Potential groundwater contaminant
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Physical state White or colourless crystalline solid
Related substances & organisms -

Formulations:
Property Value
Example manufacturers of products using this active
  • Certis
  • Chiltern
  • De Sangosse
  • Mahhteshim
  • Ypsilon SA
Example products using this active
  • Certis Deal 5
  • Meridien
  • Carakol
  • Metalden
  • Metarex
UK LERAP status None
Formulation and application details Usually supplied in ready-to-use bait.


ENVIRONMENTAL FATE

for metaldehyde

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 188 A5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) 1500 B4 - Chloroform -
530 A5 - Toluene -
1730 A5 - Methanol -
52.1 A5 - n-Hexane -
Melting point (oC) 191 A3 - (sublimes) -
Boiling point (oC) 191 A5 - (sublimes) -
Degradation point (oC) 191 A5 - (sublimes) -
Flashpoint (oC) 50 L2 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 1.32 X 1000 Calculated -
Log P 0.12 A5 Low
Bulk density (g ml-1)/Specific gravity 1.27 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 25oC (mPa) 6600 A5 Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1) 3.50 A4 Moderately volatile
Henry's law constant at 20oC (dimensionless) 5.23 X 10-01 Q2 Volatile
GUS leaching potential index 1.50 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 4.24 X 10-03 Calculated -
Note -
Potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 No significant absorption at any wavelength or pH A5 -
Surface tension (mN m-1) 71.9 A5 at 20oC -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 5.1 A4 Non-persistent
DT50 (lab at 20oC) 5.1 A5 Non-persistent
DT50 (field) - - -
DT90 (lab at 20oC) 18.1 A4 -
DT90 (field) - - -
Note EU dossier lab studies DT50 range 2.6-6.7 days, DT90 range 8.5-19.0 days; Other sources: DT50 10 days (DW4)
Aqueous photolysis DT50 (days) at pH 7 Value Stable A5 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 Very persistent
Note Stable pH 5 to pH 9 at 25 degC
Water-sediment DT50 (days) 12.2 A5 Fast
Water phase only DT50 (days) 11.5 A5 Moderately fast

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - DW3 Moderately mobile
Koc 240
Notes and range -
Freundlich Kf 0.69 B5 Moderately mobile
Kfoc 77.0
1/n 0.93
Notes and range EU dossier Kf range 0.432-0.962, Kfoc range 38-149 mL/g, 1/n range 0.91-1.02
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 91/414 relevancy
acetaldehyde Soil   0.05   Minor fraction, Relevant
paraldehyde Soil   0.004   Minor fraction, Not relevant


ECOTOXICOLOGY

for metaldehyde

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 11 A5 Low potential
CT50 (days) Negligible content after 28 days -
Bioaccumulation potential - Calculated Low
Mammals - Acute oral LD50 (mg kg-1) 283 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) > 10 B5 Rat High
(ppm diet) > 200 -
Birds - Acute LD50 (mg kg-1) 196 A5 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) > 3460 mg kg feed-1 A2 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 75 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 37.5 A5 Oncorhynchus mykiss -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 78.4 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 90 A5 Daphnia magna -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 75.9 B5 Scenedemus subspicatus Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) > 87.5 A5 Oral Moderate
Earthworms - Acute 14 day LC50 (mg kg-1) > 1000 A5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 350 A5 Aphidius rhopalosiphi Moderately harmful at 1 kg ha-1
Harmless at 0.1 kg ha-1
Harmless at 0.01 kg ha-1
% Effect - - -
Other arthropod (2) LR50 g ha-1 350 A5 Typhlodromus pyri Moderately harmful at 1 kg ha-1
Harmless at 0.1 kg ha-1
Harmless at 0.01 kg ha-1
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 6.35 mg kg-1, 28 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for metaldehyde

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) 283 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 5000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 15.0 A4 Rat, 4 hr -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.02 A4 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.3 A4 Rat, SF=100 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.1 A4 Dog, SF=100 -
Dermal penetration studies (%) 0.23 A4 -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public Negligible risk for bystanders
Occupational Acceptable risk to operators using tractor mounted equipment but risk much higher if equipment is hand held.
Examples of European MRLs (mg kg-1) Value Rape seed: 0.2; Cereals: 0.1
Note A5 EU dossier proposals
For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

General human health issues Moderately toxic
Kidney and liver toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General Highly flammable
Avoid generation of dust as dust explosion possible
Not explosive or oxidising
IMDG Transport Code is usually 4.1
CLP classification 2013 -
EC Risk Classification Xn - Harmful: R22
H - Handling risks: R11
EC Safety Classification S2, S13, S16, S25, S46
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) III, II - Caution - Slightly toxic, Warning - Moderately toxic
UN Number Usually 1332
Waste disposal & packaging Packaging Group III (minor danger)


TRANSLATIONS

for metaldehyde

Language Name
English metaldehyde
French metaldehyde
German Metaldehyd
Danish metaldehyde
Italian metaldeide
Spanish metaldehido
Greek -
Slovenian metaldehid
Polish metaldehyd
Swedish -
Hungarian metaldehyde
Dutch metaldehyde

Record last updated: Monday 06 August 2012
Contact: aeru@herts.ac.uk