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GET ADDITIONAL DATA HERE!

methoxychlor (Ref: OMS 466)
** methoxychlore ** dimethoxy-DT ** dianisyl trichloroethane ** ENT 1716 ** DMDT ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
Further data may be found in the VSDB

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for methoxychlor

Description: An insecticide effective against a wide range of pests encountered in agricultural (crops and livestock), horticulture and domestic situations

Example pests controlled: Flies, Mosquitoes; Cockroaches; Chiggers

Example applications: Liverstock pest control; Domestic gardens; Pet pest management

Efficacy & activity: -

Availability status: Current

Introduction & key dates: circa 1948

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur -
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism A prochiral molecule
Chemical formula C16H15Cl3O2
Canonical SMILES COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)C(Cl)(Cl)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) IAKOZHOLGAGEJT-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Veterinary substance
Substance group Organochlorine
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Contact and stomach action. Central nervous stimulant, producing hyperactivity, convulsions and death.
CAS RN 72-43-5
EC number 200-779-9
CIPAC number 14
US EPA chemical code 034001
PubChem CID 4115
Molecular mass (g mol-1) 345.65
PIN (Preferred Identification Name) -
IUPAC name 1,1,1-trichloro-2,2-bis(4-methoxyphenyl)ethane
CAS name 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxybenzene)
Other status information POP candidate; OSPAR pfa
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 3B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Ctenocephalides felis
Cydia pomonella
Euxoa ochrogaster
Haematobia irritans
Helicoverpa zea
many more
Physical state Colourless crystalline solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Kincaid Enterprises
Example products using this active
  • Double-M
  • Chemform
  • Moxie
  • Marlate
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Supplied in a variety of formulations including emulsifiable concentrates, wettable powders, flowables, seed treatments and aerosols .


ENVIRONMENTAL FATE

for methoxychlor

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 0.1 G4 Low
Solubility - In organic solvents at 20oC (mg l-1) 440000 L3 - Xylene -
50000 L3 - Methanol -
700000 V3 - Trichloroethane -
1333000 V2 - Dichloromethane -
Melting point (oC) 87 F3 -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P 6.76 X 1005 Calculated -
Log P 5.83 Q2 High
Bulk density (g ml-1)/Specific gravity 1.41 L3 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 20oC (mPa) 0.08 Q2 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 2.00 X 10-02 V3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -1.88 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 5.35 X 10-03 Calculated -
Note Estimated concentrations of chemicals with Koc values greater than 9995 ml g-1 are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 120 G4 Persistent
DT50 (lab at 20oC) 120 F3 Persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Best available data
Dissipation rate RL50 on plant matrix Value 6.5 R3 -
Note Cherry leaves, n=1
Dissipation rate RL50 on and in plant matrix Value 1.8 R3 -
Note Collard leaves, n=1
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - G3 Non-mobile
Koc 80000
Notes and range Best available data
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
1,1-(2,2-dichloroethylidene)bis(4-methoxybenzene) Soil   -   -


ECOTOXICOLOGY

for methoxychlor

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 1622 E3 (Other literature values Log BCF range 2.8-4.1 (R3)) Threshold for concern
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) > 6000 L3 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 200 -
Birds - Acute LD50 (mg kg-1) > 2000 F4 Anas platyrhynchos Low
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.052 L3 Oncorhynchus mykiss High
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.00078 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.6 F4 Scenedesmus quadricauda Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 23.6 F4 Moderate
Oral acute 48 hour LD50 (μg bee-1) - - -
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for methoxychlor

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 6000 L3 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 L3 Rabbit -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.1 JMPR 1977 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards Non-statutory WHO drinking water guideline 0.02 mg/L UK EA QS database, 2018 -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

-

General human health issues Endocrine issues - Strong estrogenic effect
Potential kidney toxicant
IARC Group 3 carinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Highly flammable and easily ignited by heat, sparks and flames
CLP classification 2013 -
EC Risk Classification Click here to view information omn the EU risk phrases Not classified: Obsolete
EC Safety Classification Click here to view information omn the EU safety phrases Not classified: Obsolete
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number 2761
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for methoxychlor

Language Name
English methoxychlor
French methoxychlore
German Methoxychlor
Danish methoxychlor
Italian metossicloro
Spanish metoxiclor
Greek -
Slovenian metoksiklor
Polish metoksychlor
Swedish -
Hungarian -
Dutch -

Record last updated: Wednesday 31 October 2018
Contact: aeru@herts.ac.uk