Azamethiphos (Ref: GCA 18809) |
![]() Last updated: 31/12/2020 |
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(Also known as: OMS 1825) |
SUMMARY |
Azamethiphos is an organophosphate used as an insecticide and as an antiparasitic agent for veterinary use. It does not have EU approval for use. It is highly soluble in water, volatile and not expected to leach to groundwater. Not a great deal is known about its environmental persistence. It is modertaley toxic to mammals and not expected to bioaccumulate. It is a mutagen, neurotoxicant and an acetyl cholinesterase inhibitor. Azamethiphos is highly toxic to birds and aquatic invertebrates and moderately toxic to fish. |
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A residual organophoshorus insecticide for fly control. Also has some applications in fish farming. | |
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Houseflies; Beetles; Bugs; Spiders; Sea lice; Cockroaches; Tsetse flies | |
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Residences and other buildings | |
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- | |
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Current | |
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1970 |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia |
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Chemical structure |
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C₉H₁₀ClN₂O₅PS | |
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COP(=O)(OC)SCN1C2=NC=C(C=C2OC1=O)Cl | |
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No data | |
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VNKBTWQZTQIWDV-UHFFFAOYSA-N | |
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InChI=1S/C9H10ClN2O5PS/c1-15-18(14,16-2)19-5-12-8-7(17-9(12)13)3-6(10)4-11-8/h3-4H,5H2,1-2H3 | |
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Yes |
General status |
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Insecticide, Veterinary substance | |
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Organophosphate | |
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>95% | |
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- | |
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Synthetic | |
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Contact and stomach action, rapid knockdown. Acetylcholinesterase (AChE) inhibitor. | |
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35575-96-3 | |
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252-626-0 | |
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8022 | |
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- | |
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71482 | |
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324.68 | |
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S-[(6-chloro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate | |
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S-6-chloro-2,3-dihydro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3-ylmethyl O,O-dimethyl phosphorothioate | |
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S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate | |
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- | |
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UK non-statutory standard for protection of freshwater and saltwater aquatic life 0.02 µg l⁻¹ as annual average, 0.05 as max acceptable conc. | |
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Not applicable | |
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Not applicable | |
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1B | |
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Not applicable | |
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Musca domestica | |
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Colourless to grey cystalline solid |
Formulations |
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Often supplied as a wettable powders, direct use bait formulations and as bath additives |
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1100 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
High | ||||||||
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610000 | L3 L = Pesticide manuals and hard copy reference books / other sources Dichloromethane3 = Unverified data of known source |
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130000 | L3 L = Pesticide manuals and hard copy reference books / other sources Benzene3 = Unverified data of known source |
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100000 | L3 L = Pesticide manuals and hard copy reference books / other sources Methanol3 = Unverified data of known source |
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5800 | L3 L = Pesticide manuals and hard copy reference books / other sources n-Octanol3 = Unverified data of known source |
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89 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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Decomposes before boiling | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
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150 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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1.12 X 1001 | Calculated | - | |||||||
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1.05 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Low | ||||||||
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1.6 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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0.0049 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
Low volatility | ||||||||
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1.45 X 10-06 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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0.25 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-persistent | |||||||
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Best available data, Industry data DT₅₀ in loamy sand circa 6 hours (E3) | ||||||||||
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11 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-persistent | |||||||
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pH sensitive ranging from 33 days at pH 5 to 4.3 hrs at pH 9 | ||||||||||
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Soil adsorption and mobility |
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- | S1 S = Expert judgement 1 = Estimated data with little or no verification |
Mobile | |||||||
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25 | ||||||||||
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Estimated | ||||||||||
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Fate indices |
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-1.57 | Calculated | Low leachability | ||||||||||||||||||||||||||
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2.92 X 10-04 | Calculated | - | |||||||||||||||||||||||||
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Low | Calculated | - | ||||||||||||||||||||||||||
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Mobile | Calculated | - |
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1.56 | Q2 Q = Miscellaneous internet resources Estimated2 = Unverified data of unknown source |
Low potential | |||||||
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Not available | - | |||||||||
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1180 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
Moderate | ||||||||
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2 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
High | |||||||
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20 | - | |||||||||
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> 30.2 | L3 L = Pesticide manuals and hard copy reference books / other sources Colinus virginianus3 = Unverified data of known source |
High | ||||||||
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> 0.115 | L3 L = Pesticide manuals and hard copy reference books / other sources Oncorhynchus mykiss3 = Unverified data of known source |
Moderate | ||||||||
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0.00067 | L3 L = Pesticide manuals and hard copy reference books / other sources Daphnia magna3 = Unverified data of known source |
High | ||||||||
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> 0.10 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
High | |||||||
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General |
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High (class III) | - | - | ||||||||
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1180 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
Moderate | ||||||||
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2150 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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> 0.56 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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0.003 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK ACP 20015 = Verified data used for regulatory purposes |
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0.01 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK ACP 20015 = Verified data used for regulatory purposes |
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0.1 | B5 B = UK CRD and ACP evaluation documents / and other Defra (UK) documents (click here ) UK ACP 2001 ST5 = Verified data used for regulatory purposes |
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List I; List II | - | - | ||||||||
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Health issues |
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Mutagenic potential |
Handling issues |
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IMDG Transport Code is 6.1 | |||
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Health: H302, H317, H332 Environment: H400, H410 |
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Xn - Harmful: R22 Xi - Irritant: R36 |
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S26 | |||
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II (Moderately hazardous) | |||
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2783 | |||
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azamethiphos | ||
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azametiphos | ||
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Azamethiphos | ||
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azamethiphos | ||
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azametifos | ||
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azametifos | ||
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azametifos | ||
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azametifos | ||
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azamethifos |
Record last updated: | 31/12/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |