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phorate (Ref: ENT 24042)
** timet ** AC 3911 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for phorate

Description: An insecticide used to control leaf miners, leaf beetles, whiteflies, certain nematodes and other pests

Introduction: 1954

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur UK
Date inclusion expires Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also registered in: Australia

General status:
Pesticide type Insecticide, Acaricide, Nematicide
Substance group Organophosphate
Substance origin Synthetic
Mode of action Systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 298-02-2
EC number 206-052-2
CIPAC number 173
US EPA chemical code 057201
Chiral molecule No
Chemical formula C7H17O2PS3
SMILES S=P(OCC)(SCSCC)OCC
International Chemical Identifier (InChI) InChI=1/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 260.4
PIN (Preferred Identification Name) -
IUPAC name O,O-diethyl S-ethylthiomethyl phosphorodithioate
CAS name O,O-diethyl S-[(ethylthio)methyl] phosphorodithioate
Other status information Severe Marine Pollutant
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Physical state Clear pale yellow liquid
Related substances & organisms -

Formulations:
Property Value
Example manufacturers of products using this active
  • AgroCare
  • Amvac Chemical Group
  • King Tech Corp
Example products using this active
  • Thimet
  • Phorate
  • Rampart
  • Thimenox
UK LERAP status No UK approval for use or outside scope
Formulation and application details Usually supplied as granules.


ENVIRONMENTAL FATE

for phorate

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 50 B5 Moderate
Solubility - In organic solvents at 20oC (mg l-1) Miscible L3 - Methanol -
Miscible L3 - Ethanol -
Miscible L3 - Acetone -
Melting point (oC) -15 L2 - Product -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) 110 L3 - (closed cup) -
Octanol-water partition coefficient at pH 7, 20oC P 7.24 X 1003 Calculated -
Log P 3.86 B5 High
Bulk density (g ml-1)/Specific gravity 1.17 B5 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 112 B5 Intermediate state
Henry's law constant at 25oC (Pa m3 mol-1) 5.90 X 10-01 L3 Moderately volatile
Henry's law constant at 20oC (dimensionless) 4.20 X 10-04 Q2 Volatile
GUS leaching potential index 1.40 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 2.77 X 10-02 Calculated -
Note -
Potential for particle bound transport index - Calculated High
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 63 B5 Moderately persistent
DT50 (lab at 20oC) 40 B4 Moderately persistent
DT50 (field) 63 B5 Moderately persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note Lab studies DT50 2-9 weeks, field DT50 14-18 days USA; Other sources: 50-90 days
Aqueous photolysis DT50 (days) at pH 7 Value 1.1 L3 Moderately fast
Note Degraded by UV light
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 3.2 L3 Non-persistent
Note pH sensitive: Stable pH 5 to pH 6, DT50 3.9 days at pH 9
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - B5 Slightly mobile
Koc 1660
Notes and range -
Freundlich Kf 0.89 - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 91/414 relevancy
phorate sulfoxide Soil     -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
phorate sulfone - - - -


ECOTOXICOLOGY

for phorate

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 483 F4 (Whole fish, Other literature Log BCF range 0.5-1.1 (R3)) Threshold for concern
CT50 (days) Not available -
Bioaccumulation potential - Calculated Moderate
Mammals - Acute oral LD50 (mg kg-1) 2.0 F4 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - L3 Rat -
(ppm diet) 6 -
Birds - Acute LD50 (mg kg-1) 2.25 B5 Anas platyrhynchos High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 0.013 B5 Oncorhynchus mykiss High
Fish - Chronic 21 day NOEC (mg l-1) 0.0002 Q2 Oncorhynchus mykiss -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.004 B5 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.00033 F4 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) 0.081 F3 Chironomus riparius, 2 day EC50 High
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 1.3 A4 Unknown species Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) 0.32 B5 Contact High
Earthworms - Acute 14 day LC50 (mg kg-1) 20.8 B5 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for phorate

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) 2.0 F4 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 2.5 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.06 L3 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.0007 JMPR 2004 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.003 JMPR 2004 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits [LT TWA 8hr: 0.05 mg/m3], [ST 15 mins: 0.2 mg/m3] MEL UK HSE -
Exposure Routes Public -
Occupational May be absorbed through the skin
Highly toxic by skin contact
Examples of European MRLs (mg kg-1) Value Vegetables, fruit and cereal grains: 0.05
Note Current May 2007.
For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

General human health issues Very toxic

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General No information available
CLP classification 2013 -
EC Risk Classification T+ - Very toxic: R27/28
N - Dangerous for the environment: R50, R53
EC Safety Classification S1/2, S28, S36/37, S45, S60, S61
WHO Classification Ia - Extremely hazardous
US EPA Classification (formulation) I - Danger - Highly toxic
UN Number 3018
Waste disposal & packaging -


TRANSLATIONS

for phorate

Language Name
English phorate
French phorate
German Phorat
Danish phorat
Italian forate
Spanish forato
Greek phorate
Slovenian forat
Polish forat
Swedish -
Hungarian -
Dutch foraat

Record last updated: Thursday 13 June 2013
Contact: aeru@herts.ac.uk