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GET ADDITIONAL DATA HERE!

phosmet (Ref: OMS 232)
** phthalophos ** PMP ** ENT 25705 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home
Further data may be found in the VSDB

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for phosmet

Description: An insecticide and acaricide used to control Lepidopterous larvae, aphids and other pests

Example pests controlled: Aphids; Mites; Fruit flies; Codling moth

Example applications: Orchards - applies, pears, peaches, nectarines; Citrus fruits; Vines; Potatoes; Ornamentals; Peas; Lucerne

Efficacy & activity: Phosmet-based products, according to proposed uses and target pests show at least as good efficiacy as reference products in field trials

Availability status: Current

Introduction & key dates: circa 1962

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Spain/Greece
Date inclusion expires 31/07/2019
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism -
Chemical formula C11H12NO4PS2
Canonical SMILES COP(=S)(OC)SCN1C(=O)C2=CC=CC=C2C1=O
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) LMNZTLDVJIUSHT-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3
Structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide, Veterinary substance
Substance group Organophosphate
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - phosmet oxon 0.8 g/kg max., iso phosmet: 0.4 g/kg
Substance origin Synthetic
Mode of action Non-systemic with predominately contact action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 732-11-6
EC number 211-987-4
CIPAC number 318
US EPA chemical code 059201
PubChem CID 12901
Molecular mass (g mol-1) 317.33
PIN (Preferred Identification Name) -
IUPAC name O,O-dimethyl S-phthalimidomethyl phosphorodithioate
CAS name S-((1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl) O,O-dimethyl phosphorodithioate
Other status information Marine Pollutant; Evidence of use in third world countries
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Amblyseius chilenesis
Amblyseius fallacis
Amblyseius nicholsii
Chrysoperla carnea
Myzus persicae
many others
Physical state Off-white crystalline solid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Stauffer
Example products using this active
  • Imidan 50 WP
  • Prolate
  • Kemolate
  • Appa
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Usually suppled as a wettable powder.


ENVIRONMENTAL FATE

for phosmet

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 15.2 A5 Low
Solubility - In organic solvents at 20oC (mg l-1) 53000 A5 - Xylene -
62000 A5 - Ethyl acetate -
29200 A5 - Methanol -
1040 A5 - n-Heptane -
Melting point (oC) 71.8 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 208.5 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 6.31 X 1002 Calculated -
Log P 2.8 A5 Moderate
Bulk density (g ml-1)/Specific gravity 1.44 A5 -
Dissociation constant (pKa) at 25oC Not applicable A5 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 0.065 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 1.36 X 10-03 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.25 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.33 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution: 221.9nm = 44668, 294.6nm = 1259; [Acidic solution: 222.6nm = 42658, 295.6nm = 2399; [Basic solution: 218.5nm = 16595 A5 -
Surface tension (mN m-1) 71.8 A5 at 20oC -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 3.2 A5 Non-persistent
DT50 (lab at 20oC) 3.2 A5 Non-persistent
DT50 (field) 9.6 A3 Non-persistent
DT90 (lab at 20oC) 15.65 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU 2017 dossier Lab studies DT50 1.65-4.59 days, DT90 range 5.48-25.82 days, Soils=4; field studies DT50 range 1.5-10.6 days, USA, Soils=5
Dissipation rate RL50 on plant matrix Value 1.15 R3 -
Note Tea, green leaves, n=1
Dissipation rate RL50 on and in plant matrix Value 2.7 R4 -
Note Published literature RL50 range 1.6-4.6 days, 5 field crops, various matrices, n=5
Aqueous photolysis DT50 (days) at pH 7 Value 4.5 A5 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 0.3 A5 Non-persistent
Note pH sensitive: DT50 7.5 days at pH 5, 7.8 hours at pH 7, 4.5 minutes at pH 9, all at 25 degC
Water-sediment DT50 (days) 7 A4 Fast
Water phase only DT50 (days) 4 A4 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd 6.78 A5 Slightly mobile
Koc 3534
Notes and range EU 2017 dossier Kd range 1.21-13.51 mL/g, Koc range 912-11258 mL/g, Soils=4
Freundlich Kf 10.7 A5 Slightly mobile
Kfoc 3212
1/n 0.94
Notes and range EU 2017 dossier Kf range 1.17-15.8 mL/g, Kfoc range716-10400 mL/g, 1/n range 0.89-0.98, Soils=4
pH sensitivity No

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
phthalamic acid This metabolite may cause environmental pollution, click here for further information Soil   0.169   Major fraction; relevant
phthalic acid Soil   0.083   Minor fraction; Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
N-hydroxymethyl phthalamic acid - Soil (Anaerobic) 0.145 -
N-hydroxymethylphthalimide - Water/sediment; Animal - -
O,O-dimethylphosphorodithioc acid - Water - -
O,O-dimethylphosphoric acid - Water - -
N-(methylsulfinylmethyl)-phthalamic acid PaAMS(O)M Rat (Urinary) - -
N-(methylsulfonylmethyl)-phthalamic acid PaAMS(O2)M Rat (Urinary) - -
phthalic anhydride - Plant - -
phthalimide - Plant - -
N-hydroxyphthalamic acid - Plant - -
- Phosmet oxon Plant - -
N-methlythiomethyl phthalimide - Animal (Liver) - -
N-methylsulfonylmethyl phthalamic acid - Animal (Liver) - -


ECOTOXICOLOGY

for phosmet

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 79 R3 (Based on LogP < 3 Low risk (A5)) Low potential
CT50 (days) Not available -
Mammals - Acute oral LD50 (mg kg-1) 113 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) 2 A5 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 1068 A5 Anas platyrhynchos Moderate
Birds - Short term dietary (LC50/LD50) 406 mg kg bw-1 day-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 0.24 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.032 A5 Oncorhynchus mykiss Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.002 A5 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 0.00078 A5 Daphnia magna High
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.016 F3 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.07 W2 Unknown species Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees Contact acute 48 hour LD50 (μg bee-1) 0.22 A5 Apis mellifera High
Oral acute 48 hour LD50 (μg bee-1) 0.37 A5 Apis mellifera High
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) 52 A5 Eisenia foetida, corr Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 0.144 A5 Eisenia foetida Moderate
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 1.95 48 hour
A5 Aphidius rhopalosiphi, adult
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 301 7 day
A5 Typhlodromus pyri, adult
-
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect [Dose: 2.5 kg ha-1]
Carbon mineralisation: No significant adverse effect [Dose: 3.4 kg ha-1]
A5 -
Mesocosm study data NOEAEC mg l-1 0.000813 A5 Aquatic invertebrates -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for phosmet

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 113 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 1000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 1.52 A5 Rat, 4 hr (whole body) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.01 A5 SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.045 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.02 A5 Rat, 90 day, SF=100 -
Dermal penetration studies (%) 0.1-4.0 A5 concentration dependent -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public Moderate risk to bystanders if present during spraying
Occupational Risk of being absorbed via skin or the eyes - PPE/PPC essential
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues Highly toxic by all routes
USEPA - some evidence to suggest possible human carcinogen

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Prevent generation of dust
Not explosive or oxidising
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H301, H302, H312, H332
Environment: H400, H410
EC Risk Classification Click here to view information omn the EU risk phrases T - Toxic: R25
Xn - Harmful: R21/22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S2, S22, S36/37, S60, S61
WHO Classification II - Moderately hazardous
US EPA Classification (formulation) II - Warning - Moderately toxic
UN Number 2783 for active, products usually 2811
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for phosmet

Language Name
English phosmet
French phosmet
German Phosmet
Danish phosmet
Italian fosmet
Spanish fosmet
Greek phosmet
Slovenian fosmet
Polish fosmet
Swedish -
Hungarian phosmet
Dutch fosmet

Record last updated: Thursday 23 August 2018
Contact: aeru@herts.ac.uk