Propetamphos (Ref: OMS 1502) |
![]() Last updated: 03/03/2021 |
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(Also known as: safrotin; SAN 521391) |
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A insecticide and acaricide for use in public health and livestock situations | |
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Cockroaches; Flies; Ants; Moths; Fleas; Ticks; Mosquitoes; Termites | |
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Public health applications; Landscape management; Non-cropped areas including rights-of-way, footpaths | |
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Current | |
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circa 1975 |
UK regulatory status |
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Not approved | ||
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Expired | ||
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Not applicable |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Australia |
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Chemical structure |
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Propetamophos is a chiral molecule. The technical material tends to consist of 4 isomer: 2 geometric isomers (cis & trans) and 2 optical isomers (S- and R-). The S-form is the dominate isomer and usually exceeds 90% of the techinal material. | |
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C₁₀H₂₀NO₄PS | |
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CCNP(=S)(OC)OC(=CC(=O)OC(C)C)C | |
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CCNP(=S)(OC)O/C(=C/C(=O)OC(C)C)/C | |
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BZNDWPRGXNILMS-VQHVLOKHSA-N | |
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InChI=1S/C10H20NO4PS/c1-6-11-16(17,13-5)15-9(4)7-10(12)14-8(2)3/h7-8H,6H2,1-5H3,(H,11,17)/b9-7+/f/h11H | |
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Yes |
General status |
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Insecticide, Acaricide, Veterinary substance | |
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Organophosphate | |
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Synthetic | |
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Contact and stomach action with long residual activity; Acetylcholinesterase (AChE) inhibitor. | |
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31218-83-4 | |
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250-517-2 | |
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394 | |
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113601 | |
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5372405 | |
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281.31 | |
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- | |
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(RS)-[(E)-O-2-isopropoxycarbonyl-1-methylvinyl O-methyl ethylphosphoramidothioate] | |
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1-methylethyl (2E)-3-[[(ethylamino)methoxyphosphinothioyl]oxy]-2-butenoate | |
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Marine, Surface and Groundwater Pollutant; PAN listed Highly Hazardous Chemical | |
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UK non-statutory standard for the protection of aquatic life: freshwater and saltwater annual average; 0.03 µg l⁻¹, max acceptable conc: 0.1 µg l⁻¹ | |
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Not applicable | |
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Not applicable | |
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1B | |
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Not applicable | |
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Blattella germanica, Bulex pipiens molestus, Bulex pipiens pipiens, Musca domestica, Rhipicephalus bursa | |
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Oily yellow liquid |
Formulations |
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Usually supplied as a liquid concentrate for application as spot, surface, and crack and crevice treatments via low pressure spray or injected into the soil for termites. |
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110 | G4 G = Extension Toxicology network database EXTOXNET (click here ) at 24 °C4 = Verified data |
Moderate | ||||||||
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Miscible | L3 L = Pesticide manuals and hard copy reference books / other sources Ethanol3 = Unverified data of known source |
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Miscible | L3 L = Pesticide manuals and hard copy reference books / other sources Methanol3 = Unverified data of known source |
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Miscible | L3 L = Pesticide manuals and hard copy reference books / other sources Xylene3 = Unverified data of known source |
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Miscible | L3 L = Pesticide manuals and hard copy reference books / other sources Hexane3 = Unverified data of known source |
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Not applicable | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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87 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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6.61 X 1003 | Calculated | - | |||||||
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3.82 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
High | ||||||||
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1.13 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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13.67 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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Strong base | |||||||||||
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1.9 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Low volatility | ||||||||
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4.87 X 10-03 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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20 | S1 S = Expert judgement 1 = Estimated data with little or no verification |
Non-persistent | |||||||
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30 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Moderately persistent | ||||||||
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Best available data | ||||||||||
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Stable | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Stable | |||||||
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120 | C4 C = AGRITOX (click here ) 4 = Verified data |
Persistent | |||||||
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Other data: DT₅₀ 11 days at pH 3, 1 year at pH 6, 41 days at pH 9, all at 25 °C (L3) | ||||||||||
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Soil adsorption and mobility |
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- | US3 US = US Dept of Agriculture National Resources Conservation Service - various datasheets, databases and online sources 3 = Unverified data of known source |
Moderately mobile | |||||||
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330 | ||||||||||
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Best available data | ||||||||||
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Fate indices |
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2.19 | Calculated | Transition state | ||||||||||||||||||||||||||
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9.27 X 10-02 | Calculated | - | |||||||||||||||||||||||||
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Low | Calculated | - | ||||||||||||||||||||||||||
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Moderately mobile | Calculated | - |
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352 | Q2 Q = Miscellaneous internet resources Estimated2 = Unverified data of unknown source |
Threshold for concern | |||||||
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Not available | - | |||||||||
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75 | G4 G = Extension Toxicology network database EXTOXNET (click here ) Rat4 = Verified data |
High | ||||||||
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- | L2 L = Pesticide manuals and hard copy reference books / other sources Rat 2 year2 = Unverified data of unknown source |
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6 | - | |||||||||
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45 | G4 G = Extension Toxicology network database EXTOXNET (click here ) Anas platyrhynchos4 = Verified data |
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4.6 | L3 L = Pesticide manuals and hard copy reference books / other sources Oncorhynchus mykiss3 = Unverified data of known source |
Moderate | ||||||||
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0.015 | L3 L = Pesticide manuals and hard copy reference books / other sources Daphnia magna3 = Unverified data of known source |
High | ||||||||
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0.0001 | P3 P = Other governments and regulators Daphnia magna3 = Unverified data of known source |
High | ||||||||
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2.9 | L3 L = Pesticide manuals and hard copy reference books / other sources Pseudokirchneriella subcapitata3 = Unverified data of known source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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75 | G4 G = Extension Toxicology network database EXTOXNET (click here ) Rat4 = Verified data |
High | ||||||||
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2260 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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0.69 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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List I; List II | - | - | ||||||||
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Health issues |
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No further information available |
Handling issues |
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No information available | |||
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Health: H301 Environment: H400, H410 |
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T - Toxic: R25 N - Dangerous for the environment: R50, R53 |
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S1/2, S37, S45, S60, S61 | |||
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Ib (Highly hazardous / Highly hazardous) | |||
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3018 | |||
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propetamphos | ||
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propetamphos | ||
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Propetamphos | ||
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propetamphos | ||
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propetamfos | ||
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propetamfos | ||
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propetamphos | ||
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propetamfos | ||
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Record last updated: | 03/03/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |