Pyriprole (Ref: V3086)
Last updated: 26/04/2021
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
An animal health insecticide, that is an analogue of fipronil, used for the treatment for fleas and ticks on animals.
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2004, USA
Domestic and farmed animals
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C₁₈H₁₀Cl₂F₅N₅S
C1=CC=NC(=C1)CNC2=C(C(=NN2C3=C(C=C(C=C3Cl)C(F)(F)F)Cl)C#N)SC(F)F
No data
MWMQNVGAHVXSPE-UHFFFAOYSA-N
InChI=1S/C18H10Cl2F5N5S/c19-11-5-9(18(23,24)25)6-12(20)14(11)30-16(28-8-10-3-1-2-4-27-10)15(31-17(21)22)13(7-26)29-30/h1-6,17,28H,8H2
Yes
Insecticide, Antiparasitic, Acaricide
Phenylpyrazole
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Synthetic
Causes uncontrolled activity of parasites nervous system and hence its death, broad-spectrum, non-systemic
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394730-71-3
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QP53AX26
Antiparasitic products, insecticides & repellents: Ecoparasiticides, insecticides & repellents
No
No data
494.27
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1-(2,6-dichloro-α,α,α-trifluoro-para-tolyl)-4-(difluoromethylthio)-5-[(2-pyridylmethyl)amino]pyrazole-3-carbonitrile
1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(difluoromethyl)thio]-5-[(2-pyridinylmethyl)amino]-1H-pyrazole-3-carbonitrile
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Pale yellow liquid
Prac-tic Spot On Solution for Dogs
Novartis Sanidad Animal S.L.
EU Centralised procedure
Prescription only medicine to be authorised by a veterinarian (POM-V)
Often supplied as a spot treatment for the skin
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Soil adsorption and mobility
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Terrestrial ecotoxicology
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HUMAN HEALTH AND PROTECTION
High (class III)
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Around 50% of that applied is absorbed by skin eventually excreted mainly via the faeces with lesser amounts in the urine. Elimnation is slow.
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
No further information available
Not authorised for use on humans
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Not listed (Not listed)
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pyriprole
pyriprole
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Record last updated:
26/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242