Fluazuron (Ref: CGA 157419)
Last updated: 15/04/2021
(Also known as: ixodicide)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
Insect growth regulator and broad spectrum antiparasitic substance used to control ticks in livestock, especially cattle
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Farmed livestock
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C₂₀H₁₀Cl₂F₅N₃O₃
C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2)Cl)OC3=C(C=C(C=N3)C(F)(F)F)Cl)F
No data
YOWNVPAUWYHLQX-UHFFFAOYSA-N
InChI=1S/C20H10Cl2F5N3O3/c21-11-5-4-10(29-19(32)30-17(31)16-13(23)2-1-3-14(16)24)7-15(11)33-18-12(22)6-9(8-28-18)20(25,26)27/h1-8H,(H2,29,30,31,32)
Yes
Acarcide, Insecticide, Ioxodicide
Benzoylphenyl urea
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Synthetic
Chitin synthesis inhibitor. Treated immature ticks are unable to moult to the next stage, and no larvae will hatch from eggs laid by treated females
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86811-58-7
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Not listed
None
No
Allowed substance (Table 1: Bovine)
506.21
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1-[4-chloro-3-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenyl]-3-(2,6-difluorobenzoyl)urea
N-[[[4-chloro-3-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]amino]carbonyl]-2,6-difluorobenzamide
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White to pale pink fine crystalline powder
None identified
None identified
No UK authorisation for use with animals
Not applicable
Typically used as a pour-on
0.02
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
Low
2400
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
Methanol
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900
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
Isopropanol
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700
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
n-Octanol
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30000
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
Hexane
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219
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
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219
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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1.26 X 1005
Calculated
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5.1
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
High
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1.59
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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1.2 X 10-07
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
3.04 X 10-06
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
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Soil adsorption and mobility
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Known soil and groundwater metabolites
None
3-[3-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)-4-chloro-6-hydroxyphenyl]urea
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Rats
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Terrestrial ecotoxicology
> 5000
Rat
Low
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> 2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Anas platyrhynchos
Low
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1000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderate
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15
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
Moderate
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0.0006
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
High
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27.9
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Unknown species
Low
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 5000
Rat
Low
200
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
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5.99
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat 4 hr
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Mainly eliminated as metabolites in the faeces
FAO3 FAO = Miscellaneous FAO publications 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
XNo, known not to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
XNo, known not to cause a problem
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
?Possibly, status not identified
No data found
 
No further information available
No information available
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III (Slightly hazardous)
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fluazuron
fluazuron
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fluazurón
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Record last updated:
15/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242