Chloroxylenol
Last updated: 22/01/2023
(Also known as: 2-chloro-m-xylenol; p-chloro-m-xylenol )
Chloroxylenol is a bactericide and antiseptic used mainly in public health situations. Available data is limited. It is moderately toxic to aquatic species. Mammalian toxicity is low and, whilst it may be an eye irritant, no data is available that suggests it may cause more serious health impacts unless dosages are high.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A substance used as an aid in the treatment of minor wounds and skin conditions.
Current
1959, USA
Cats, Dogs
None
C₈H₉ClO
CC1=CC(=CC(=C1Cl)C)O
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OSDLLIBGSJNGJE-UHFFFAOYSA-N
InChI=1S/C8H9ClO/c1-5-3-7(10)4-6(2)8(5)9/h3-4,10H,1-2H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
chloroxylenol
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Disinfectant, Bactericide, Antiseptic
Chlorinated phenol compound; Unclassified pesticide
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Synthetic
Causes disruption of cell membrane potentials, blocking production of adenosine triphosphate
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88-04-0
201-793-8
None allocated
086801
2723
604-038-00-4
QD08AE99
Dermatologicals: Antiseptics and disinfectants
No
No data
156.61
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4-chloro-3,5-dimethylphenol
chloroxylenol
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Colourless oily liquid with pleasant aromatic odour
Vetzyme Antiseptic Cutaneous Powder
Bob Martin (UK) Ltd
UK National authorisation
Authorised veterinary medicine for general sale (AVM - GSL)
Formulated as ready-to-use liquids, creams and as liquid concentrates
250
Moderate
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115
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246
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1.86 X 1003
Calculated
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3.27
High
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1.12
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
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9.7
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Soil adsorption and mobility
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None
Terrestrial ecotoxicology
3830
Rat
Low
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1.6
Lepomis macrochirus
Moderate
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6.7
Daphnia magna
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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3830
Rat
Low
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Intraperitoneal LD₅₀ = 115000 mg kg⁻¹
Mouse
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Excreted in the urine as a glucuronide conjugate and as the sulfate together with some unchanged chemical
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
?Possibly, status not identified
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
IARC Carcinogen: 2B May cause nausea, vomiting, and diarrhoea May cause pulmonary edema and neurological changes Possible liver and renal toxicant
Highly corrosive
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NL (Not listed)
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chloroxylenol
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cloroxilenol
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Record last updated:
22/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242