Kitasamycin |
![]() Last updated: 21/04/2021 |
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(Also known as: selectomycin; leucomycin; antibiotic A 6599; stereomycine; turimycin) |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A macrolide antibiotic drug produced by streptomyces kitasatoensis and which has antimicrobial activity against a wide spectrum of Gram-positive pathogens | |
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1960, developed | |
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Pigs, Poultry |
Chemical structure |
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Isomeric | |
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C₃₅H₅₉NO₁₃ | |
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CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)O | |
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C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O | |
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XYJOGTQLTFNMQG-KJHBSLKPSA-N | |
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InChI=1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1 | |
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Yes |
General status |
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Antibiotic, Antibacterial, Antimicrobial, Medicinal drug, Growth promotor, Feed additive | |
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Macrolide | |
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Natural | |
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Inhibits the protein synthesis process | |
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[50S rRNA, antagonist] | |
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39405-35-1 | |
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QJ01FA93 | |
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Antiinfectants for systemic use: Antibacterials for system use | |
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No | |
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No data | |
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701.84 | |
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2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan- 2-yl]oxy-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-4,10-dihydroxy- 5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde | |
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Evidence of use in third world countries | |
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White crystalline solid |
Formulations |
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None identified | None identified | No UK authorisation for use with animals | Not applicable | ||||||
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Usually supplied as a premix feed |
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Degradation |
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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4965 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
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Aquatic ecotoxicology |
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General |
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High (class III) | - | - | ||||||||
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4965 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
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Intraperitoneal LD₅₀ = 711 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
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Intravenous LD₅₀ = 320 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Mouse3 = Unverified data of known source |
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Mainly excreted through hepatobiliary system, mostly in bile and faeces with lesser amounts lost in urine | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
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Health issues |
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May cause gastrointestinal problems |
Handling issues |
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No information available | |||
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None - not a ppp | |||
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kitasamycin | ||
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Record last updated: | 21/04/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |