Flavomycin |
![]() Last updated: 15/04/2021 |
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(Also known as: flavomicin; bambermycin; flavophospholipol; moenomycin A; BAM) |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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![]() Significant data are missing |
![]() Significant data are missing |
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An antibiotic drug effective against Gram-positive bacteria, that is used to promote increased weight gain and improved feed efficiency in a range of farmed animals | |
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- | |
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circa 1968 | |
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Pigs, Poultry, Cattle, Rabbits, Aquatic species |
Chemical structure |
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Isomeric | |
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C₆₉H₁₀₇N₄O₃₅P | |
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CC1C(C(C(C(O1)OC2C(OC(C(C2O)NC(=O)C)OC3C(C(C(OC3OP(=O)(O)OCC(C(=O)OCCC=C(C)CCC=CC(C)(C)CCC(=C)CC=C(C)CCC=C(C)C)O)C(=O)O)(C)O)OC(=O)N)COC4C(C(C(C(O4)CO)O)O)O)NC(=O)C)O)OC5C(C(C(C(O5)C(=O)NC6=C(CCC6=O)O)O)O)O | |
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C[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)NC(=O)C)O[C@@H]3[C@H]([C@]([C@H](O[C@@H]3OP(=O)(O)OC[C@H](C(=O)OCC/C=C(\C)/CC/C=C/C(C)(C)CCC(=C)C/C=C(\C)/CCC=C(C)C)O)C(=O)O)(C)O)OC(=O)N)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)NC(=O)C)O)O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)C(=O)NC6=C(CCC6=O)O)O)O)O | |
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FUIOWSNNCWZETH-NAMXWVJMSA-N | |
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InChI=1S/C70H109N4O35P/c1-31(2)16-14-18-33(4)20-21-34(5)24-26-69(9,10)25-13-12-17-32(3)19-15-27-97-62(92)40(80)29-99-110(95,96)109-67-57(58(108-68(71)93)70(11,94)59(107-67)61(90)91)106-64-45(73-37(8)77)48(83)55(42(102-64)30-98-65-52(87)49(84)46(81)41(28-75)101-65)104-63-44(72-36(7)76)47(82)54(35(6)100-63)103-66-53(88)50(85)51(86)56(105-66)60(89)74-43-38(78)22-23-39(43)79/h13,16,19-20,25,35,40-42,44-59,63-67,75,78,80-88,94H,5,12,14-15,17-18,21-24,26-30H2,1-4,6-11H3,(H2,71,93)(H,72,76)(H,73,77)(H,74,89)(H,90,91)(H,95,96)/b25-13+,32-19+,33-20+/t35-,40-,41-,42-,44-,45-,46-,47-,48-,49+,50+,51-,52-,53-,54-,55-,56+,57-,58-,59-,63+,64+,65-,66-,67-,70+/m1/s1 | |
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Yes |
General status |
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Antibiotic, Antibacterial, Antimicrobial, Performance enhancer, Feed additive | |
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Phosphoglycolipid | |
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Natural | |
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Broad spectrum, inhibits microorganism reproduction by intervening in the biosynthesis of murein, the structural substance of their cell walls. | |
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[Peptidoglycan synthetase ftsI, antagonist] | |
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11015-37-5 | |
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234-246-7 | |
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Not listed | |
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None | |
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No | |
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No data | |
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1583.57 | |
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(2S,3S,4R,5R,6R)-5-[(2S,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-methyl-5-[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2-hydroxy-5-oxocyclopenten-1-yl)carbamoyl]oxan-2-yl]oxyoxan-2-yl]oxy-4-hydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-4-carbamoyloxy-3-hydroxy-6-[hydroxy-[(2R)-2-hydroxy-3-oxo-3-[(3E,7E,14E)-4,9,9,15,19-pentamethyl-12-methylideneicosa-3,7,14,18-tetraenoxy]propoxy]phosphoryl]oxy-3-methyloxane-2-carboxylic acid | |
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Evidence of use in third world countries | |
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White to light brown coloured powder |
Formulations |
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Flavomycin 40 | Huvepharma | No UK authorisation for use | Not applicable | ||||||
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Usually adnimistered orally, following good homogenization with feed. |
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250000 | E4 E = Manufacturers safety data sheets at 25 °C4 = Verified data |
High | ||||||||
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64000 | E4 E = Manufacturers safety data sheets Methanol4 = Verified data |
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500 | E4 E = Manufacturers safety data sheets Ethanol4 = Verified data |
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100 | E4 E = Manufacturers safety data sheets Acetone4 = Verified data |
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100 | E4 E = Manufacturers safety data sheets Benzene4 = Verified data |
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1.91 X 10-12 | Calculated | - | |||||||
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-11.72 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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Degradation |
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21 | E4 E = Manufacturers safety data sheets 4 = Verified data |
Non-persistent | |||||||
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21 | E4 E = Manufacturers safety data sheets 4 = Verified data |
Non-persistent | ||||||||
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DT₅₀ range 13.3 to 28.0 days, n=4; Other data DT₅₀ <30 days (R4) | ||||||||||
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<30 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Manure data for aminoglycosides generally; Other data <25 days soil & chicken manure (R3)3 = Unverified data of known source |
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 2000 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
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> 25000 | E3 E = Manufacturers safety data sheets Eisenia foetida for product (8%)3 = Unverified data of known source |
Low | ||||||||
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Aquatic ecotoxicology |
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598 | E3 E = Manufacturers safety data sheets Leuciscus idus for product (8%)3 = Unverified data of known source |
Low | ||||||||
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250 | E3 E = Manufacturers safety data sheets Leuciscus idus for product (8%)3 = Unverified data of known source |
Low | ||||||||
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908 | E3 E = Manufacturers safety data sheets Daphnia magna for product (8%)3 = Unverified data of known source |
Low | ||||||||
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433 | E2 E = Manufacturers safety data sheets Daphnia magna. 48 hour product (8%)2 = Unverified data of unknown source |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 2000 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
Low | ||||||||
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Subcutaneous LD₅₀ = 500 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Mouse3 = Unverified data of known source |
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Intravenous LD₅₀ = 200 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Mouse3 = Unverified data of known source |
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Mostly unmetabolised and excreted unchanged in the faeces | E4 E = Manufacturers safety data sheets 4 = Verified data |
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Health issues |
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No further information available |
Handling issues |
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Risk of dust explosions | |||
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Not listed (Not listed) | |||
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flavomycin | ||
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bambermycine | ||
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bambermicina | ||
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Record last updated: | 15/04/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |