Sulphapyridine
Last updated: 17/08/2023
(Also known as: sulfapyridine)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An antibiotic drug with a range of uses including the treatment of mastitis in cattle
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1937, discovered
Cattle
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C₁₁H₁₁N₃O₂S
C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N
No data
GECHUMIMRBOMGK-UHFFFAOYSA-N
InChI=1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
sulphapyridine
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Antibacterial, Antibiotic, Antimicrobial, Medicinal drug
Sulfonamide
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Synthetic
Inhibits DNA and RNA synthesis
[Dihydropterate synthase, antognist]
144-83-2
205-642-7
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QJ01EQ04
Antiinfectants for systemic use: Antibacterials for system use
No
No data
249.29
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4-amino-N-pyridin-2-ylbenzenesulfonamide
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White to yellow crystalline solid
None identified
None identified
No UK authorisation for use with animals
Not applicable
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268
Moderate
2.27
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Ethanol
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15.4
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Acetone
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192
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2.24 X 1000
Calculated
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0.35
Low
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8.43
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8.36
Moderately volatile
1.09 X 10-11
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-volatile
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Soil adsorption and mobility
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R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Moderately mobile
150
Literature Koc data range 101-308 mL g⁻¹ for silt loam, 80-218 mL g⁻¹ for soil generally
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Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
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None
Terrestrial ecotoxicology
> 15800
Rat
Low
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0.12
R2 R = Peer reviewed scientific publications 2 = Unverified data of unknown source
Green algae
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 15800
Rat
Low
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Intravenous LD₅₀ > 15800 mg kg⁻¹
Rat
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Intraperitoneal LD₅₀ = 1150 mg kg⁻¹
Mouse
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Some metabolism and largely eliminated via the urine
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E1 E = Unspecified genotoxicity type (miscellaneous data source) 1 = Positive
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May cause dermatological problems including dermatitis May cause gastrointestinal problems Possible blood, bone marrow and kidney toxicant
Non-hazardous for air, sea and road freight Light sensitive
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Not listed (Not listed)
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sulphapyridine
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2-Sulfanilamidopyridin
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sulfapiridina
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Record last updated:
17/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242