Trenbolone acetate
Last updated: 04/08/2022
(Also known as: TbA; 17beta-trenbolone Acetate)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An anabolic steroid used in many countries to increase muscle mass and appetite of livestock especially cattle
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Cattle
Isomeric mixture
C₂₀H₂₄O₃
CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2O
C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2O
MEHHPFQKXOUFFV-OWSLCNJRSA-N
InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-17,20H,2-7H2,1H3/t15-,16+,17+,18+/m1/s1
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
trenbolone acetate
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Steroid, Medicinal drug, Hormone, Growth promotor
Unclassified substance
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Synthetic
Thought to significantly increase the circulating levels of IGF-1 and decreases the normal loss of muscle in sedentary animals
[Androgen receptor, agonist]
10161-33-8
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None
None
No data
No data
312.39
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17β-(acetyloxy)estra-4,9,11-trien-3-one
3-oxo-17-β-hydroxy-4,9,11-estratriene acetate
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Pale yellow crystalline powder
Synovex Choice
Fort Dodge Animal Health
No UK authorisation for use with animals
No
Revalor-S
MSD Animal Health
No UK authorisation for use with animals
No data
Component TE-H
Ivy Animal Health Inc
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Various formulations available including ear implants
20
Low
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93
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0.3
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-persistent
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Literature states that DT₅₀ ranges from a few hours to 0.5 days
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Soil adsorption and mobility
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R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Very mobile
3.08
Isomer dependent Koc range 2.77-3.38 mL g⁻¹
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-1.84
Calculated
Low leachability
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Known soil and groundwater metabolites
None
trenbolone-17beta
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Animals; Human
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trendione
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Animals; Human
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trenbolone-17alpha
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Animals; Human
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Terrestrial ecotoxicology
> 5000
Rat
Low
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0.00005
Pimephales promelas
High
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 5000
Rat
Low
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Mainly eliminated unchanged via excreta and bile
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
✓Yes, known to cause a problem
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Potentially harmful to reproductive organs Possible liver toxicant
Reactive with acids, alkalis and oxidising agents
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None - not a ppp
Not controlled
Packaging Group II (medium danger)
trenbolone acetate
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Trembolona
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Record last updated:
04/08/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242