The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate High alert: Drainflow: Very mobile
Warning: Significant data are missing
Ecotoxicity High alert: Fish chronic ecotoxicity: High
Warning: Significant data are missing
Human health High alert: Endocrine disrupter; Reproduction/development effects
GENERAL INFORMATION
Description
An anabolic steroid used in many countries to increase muscle mass and appetite of livestock especially cattle
Thought to significantly increase the circulating levels of IGF-1 and decreases the normal loss of muscle in sedentary animals
Molecular targets
[Androgen receptor, agonist]
CAS RN
10161-33-8
EC number
-
CIPAC number
-
US EPA chemical code
-
PubChem CID
-
ATCvet Code
None
Therapeutic Class
None
Controlled Drug?
No data
Regulation 37/2010 MRL Classification
No data
Molecular mass
312.39
PIN (Preferred Identification Name)
-
IUPAC name
17β-(acetyloxy)estra-4,9,11-trien-3-one
CAS name
3-oxo-17-β-hydroxy-4,9,11-estratriene acetate
Other status information
-
Relevant Environmental Water Quality Standards
-
Physical state
Pale yellow crystalline powder
Formulations
Property
Product
Manufacturer
Authorisation Route
UK Legal Class
Example products using this active
Synovex Choice
Fort Dodge Animal Health
No UK authorisation for use with animals
No
Revalor-S
MSD Animal Health
No UK authorisation for use with animals
No data
Component TE-H
Ivy Animal Health Inc
-
-
Formulation and application details
Various formulations available including ear implants
ENVIRONMENTAL FATE
Property
Value
Source; quality score; and other information
Interpretation
Solubility - In water at 20 °C (mg l⁻¹)
20
F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source
Low
Solubility - In organic solvents at 20 °C (mg l⁻¹)
-
-
-
Melting point (°C)
93
F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source
-
Boiling point (°C)
-
-
-
Degradation point (°C)
-
-
-
Flashpoint (°C)
-
-
-
Octanol-water partition coefficient at pH 7, 20 °C
P
-
-
-
Log P
-
-
-
Fat solubility of residues
Solubility
-
-
-
Data type
-
-
-
Density (g ml⁻¹)
-
-
-
Dissociation constant pKa) at 25 °C
-
-
-
-
Vapour pressure at 20 °C (mPa)
-
-
-
Henry's law constant at 25 °C (Pa m³ mol⁻¹)
-
-
-
Maximum UV-vis absorption L mol⁻¹ cm⁻¹
-
-
-
Surface tension (mN m⁻¹)
-
-
-
Refractive Index
-
-
-
Degradation
Property
Value
Source; quality score; and other information
Interpretation
Soil degradation (days) (aerobic)
DT₅₀ (typical)
0.3
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-persistent
DT₅₀ (lab at 20 °C)
-
-
-
DT₅₀ (field)
-
-
-
DT₉₀ (lab at 20 °C)
-
-
-
DT₉₀ (field)
-
-
-
Note
Literature states that DT₅₀ ranges from a few hours to 0.5 days
Manure DT₅₀ (days)
-
-
-
Aqueous photolysis DT₅₀ (days) at pH 7
Value
-
-
-
Note
-
Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7
Value
-
-
-
Note
-
Water-sediment DT₅₀ (days)
-
-
-
Water phase only DT₅₀ (days)
-
-
-
Soil adsorption and mobility
Property
Value
Source; quality score; and other information
Interpretation
Linear
Kd
-
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242
Environmental fate
Warning:
