Atenolol
Last updated: 30/08/2023
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A human and veterinary drug used to control and regulate heart rate as well as reducing blood pressure
Not applicable
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Dogs; Cats
Isomeric existing the (R)- and (S)-forms
C₁₄H₂₂N₂O₃
CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O
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METKIMKYRPQLGS-UHFFFAOYSA-N
InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
atenolol
Isomer mix
(S)-Atenolol
S-isomer
Medicinal drug: Beta blocker
Unclassified substance
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-
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A selective ß1 receptor antagonist
[Beta-1 adrenergic receptor, Antagonist], [Beta-2 adrenergic receptor, Unknow activity]
29122-68-7
249-451-7
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2249
QC07AB03
Beta blocking agent: seelctive
No
-
266.34
(RS)-2-(4-(2-hydroxy-3-(propan-2-ylamino)propoxy)phenyl)acetamide
(RS)-2-(4-(2-hydroxy-3-(propan-2-ylamino)propoxy)phenyl)acetamide
2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-acetamide
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-
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13300
High
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147
-
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-
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1.45 X 1000
Calculated
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0.16
Low
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-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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25
Non-persistent
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
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-
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-
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Soil adsorption and mobility
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None
Terrestrial ecotoxicology
> 2000
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Rat
Low
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-
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-
-
-
-
-
-
-
-
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-
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-
-
-
-
-
-
-
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> 100
Danio rerio
Low
-
-
-
313
Daphnia magna
Low
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
620
Desmodesmus subspicatus
Low
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-
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-
HUMAN HEALTH AND PROTECTION
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> 2000
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Rat
Low
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Intravenous LD₅₀ = 84 mg kg⁻¹
Rat
-
Subcutaneous LD₅₀ > 600 mg kg⁻¹
Rat
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Hepatic metabolism, 50% absorbed through the gastrointestinal tracts and the rest excreted in the faeces
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
May cause lethargy, vomiting and diarrhoea Potential CNS toxicant
No information available
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Not listed (Not listed)
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atenolol
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Record last updated:
30/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242