Deracoxib
Last updated: 08/04/2021
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
A NSAID used to treat osteoarthritis and post-operative pain mainly in dogs
Current
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Dogs
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C₁₇H₁₄F₃N₃O₃S
COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)F
No data
WAZQAZKAZLXFMK-UHFFFAOYSA-N
InChI=1S/C17H14F3N3O3S/c1-26-16-7-2-10(8-13(16)18)15-9-14(17(19)20)22-23(15)11-3-5-12(6-4-11)27(21,24)25/h2-9,17H,1H3,(H2,21,24,25)
Yes
Medicinal drug: NSAID
Coxib
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Synthetic
A selective Cyclooxygenase (COX-2) Inhibitor
[Deracoxib inhibitor]
169590-41-4
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QM01AH94
Antiinflammatory and antirheumatic products, non-steroids: Coxibs
No
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397.38
4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazole-1-yl)benzenesulfonamide
4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazole-1-yl)benzenesulfonamide
4-(5-(3-difluoro-4-methoxyphenyl)-(difluoromethyl)-1H-pyrazole-1-yl) benzenesulfonamide
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Brown speckled powder
Deramaxx 2.5mg Chewable Tablets
Novartis
No UK national authorisation
Not applicable
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157
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Not highly flammable: Not expected to self-ignite
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Soil adsorption and mobility
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None
Terrestrial ecotoxicology
> 800
Rat
Moderate
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HUMAN HEALTH AND PROTECTION
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> 800
Rat
Moderate
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Hepatic metabolism, rapdily excreted in the faeces
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
?Possibly, status not identified
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
May cause gastro-intestinal disturbances Possible kidney toxicant May cause lethagy, incoordination and behavioural change May cause jaundice
Non-corrosive
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Not listed (Not listed)
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deracoxib
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Record last updated:
08/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242