Robenacoxib
Last updated: 14/09/2023
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A veterinary drug used for pain, fever and inflamation relief in cats and dogs especially that associated with musculoskeletal disorders
Current
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Cats; Dogs
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C₁₆H₁₃F₄NO₂
CCC1=CC(=C(C=C1)NC2=C(C(=CC(=C2F)F)F)F)CC(=O)O
No data
ZEXGDYFACFXQPF-UHFFFAOYSA-N
InChI=1S/C16H13F4NO2/c1-2-8-3-4-12(9(5-8)6-13(22)23)21-16-14(19)10(17)7-11(18)15(16)20/h3-5,7,21H,2,6H2,1H3,(H,22,23)
Yes
Medicinal drug: NSAID
Coxib
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Synthetic
Selectively inhibits the cyclooxygenase 2 enzyme (COX-2).
[Cyclo-oxygenase 2 (COX-2), Inhibitor]
220991-32-2
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QM01AH91
Anti-inflammatory and antirheumatic products: Coxibs
No
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327.28
2-(5-ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl)acetic acid
(5-ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic acid
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Soild
Onsior 10 mg Tablets for Dogs
Elanco Europe Ltd
EU Centralised procedure
Prescription only medicine to be authorised by a veterinarian (POM-V)
Onsior 20 mg/ml Solution for Injection for Cats and Dogs
Elanco Europe Ltd
EU Centralised procedure
Prescription only medicine to be authorised by a veterinarian (POM-V)
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1.06
E4 E = Manufacturers safety data sheets 4 = Verified data
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Soil adsorption and mobility
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None
Terrestrial ecotoxicology
> 500
Rat
Moderate
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> 100
E4 E = Manufacturers safety data sheets 4 = Verified data
Daphnia magna
Low
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> 100
E4 E = Manufacturers safety data sheets 4 = Verified data
Selenastrum capricornutum
Low
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HUMAN HEALTH AND PROTECTION
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> 500
Rat
Moderate
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Intraperitoneal LD₅₀ > 200 mg kg⁻¹
Rat
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Excreted predominately via the biliary route in dogs & cats
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
May induce gastrointestinal problems including vomiting and diarrhoea
May produce harmful or irritant substances when heated to decomposition
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Not listed (Not listed)
None allocated
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robenacoxib
robénacoxib
Robénacoxib
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robénacoxib
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Record last updated:
14/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242