Pyraclofos (Ref: OMS 3040)
Last updated: 23/01/2023
(Also known as: TIA 230)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Substance used for treating animals infected with internal and external parasites such as helminths, nematodes, ticks and others
-
1989, Japan
Cattle, Horses, Sheep, Pigs, Poultry, Domestic pets
A molecule with one chiral centre resulting in a pair of enantiomers: S-(+)- and R-(−)-pyraclofos
C₁₄H₁₈ClN₂O₃PS
CCCSP(=O)(OCC)OC1=CN(N=C1)C2=CC=C(C=C2)Cl
No data
QHGVXILFMXYDRS-UHFFFAOYSA-N
InChI=1S/C14H18ClN2O3PS/c1-3-9-22-21(18,19-4-2)20-14-10-16-17(11-14)13-7-5-12(15)6-8-13/h5-8,10-11H,3-4,9H2,1-2H3
Yes
Antiparasitic, Insecticide
Organophosphate insecticide; Orgnothiophosphate insecticide; Phenylpyrazole insecticide
-
-
Synthetic
Respiratory, contact and stomach action. Is an inhibitor of acetylcholinesterase.
[Cholinesterase, inhibitor]
89784-60-1
77458-01-6
618-301-6
None allocated
-
93460
No data found
-
-
No
No data
360.8
-
(RS)-[O-1-(4-chlorophenyl)pyrazol-4-yl O-ethyl S-propyl phosphorothioate]
O-[1-(4-chlorophenyl)-1H-pyrazol-4-yl] O-ethyl S-propyl phosphorothioate
Evidence of use in third world countries; PAN listed Highly Hazardous Chemical
-
Pale yellow oil
Coopers Colleague Broad Spectrum Sheep & Lamb Drench
Schering-Plough Animal Health
No UK authorisation for use with animals
Not applicable
Available in a variety of formulations including emulsifiable concentrates, granules and wettable powders.
33
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
Miscible
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Acetone
-
Miscible
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Ethanol
-
Miscible
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Methanol
-
Not applicable
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
454
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
-
-
5.89 X 1003
Calculated
-
3.77
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
-
-
-
-
-
-
1.271
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
-
-
-
-
-
1.60 X 10-03
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
1.75 X 10-05
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
-
-
-
-
-
-
-
-
-
39
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Moderately persistent
-
-
-
50
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Moderately persistent
-
-
-
-
-
-
Best available data
-
-
-
-
-
-
-
29
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-persistent
-
-
-
-
-
-
-
Soil adsorption and mobility
-
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Slightly mobile
2095
Estimated
-
-
-
-
-
-
-
1.15
Calculated
Low leachability
-
-
-
-
-
Known soil and groundwater metabolites
None
1-(4-chlorophenyl)pyrazol-4-yl-beta-D-glcopyranoside
-
Plant
-
-
des-S-propylpyraclofos
-
Rat (Urine, Faecal)
-
-
O-ethyl-S-propyl-phosphorothioate
-
Rat (Urine)
-
-
monoethylphosphate
-
Rat (Urine)
-
-
1-(4-chlorophenyl)pyrazol-4-yl-6-O-malonyl-beta-D-glcopyranoside
-
Plant
0.51
-
1-(4-chlorophenyl)pyrazo-4-yl sulfate
-
Rat (Urine)
0.7
-
desethylpyraclofos
-
Rat (Urine, Faecal)
-
-
Terrestrial ecotoxicology
237
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
0.1
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 2 year
High
-
-
-
-
-
164
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Colinus virginianus
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.953
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Apis mellifera
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.028
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Cyprinidae
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
237
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
Moderate
2000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
1.46
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
List I; List II
-
-
-
-
Rapidly absorbed, metabolised and excreted in the urine
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
-
Carcinogen
Endocrine disruptor
?Possibly, status not identified
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
?Possibly, status not identified
?Possibly, status not identified
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
Harmful if swallowed
IMDG Transport Code is usually 6.1
Health: H301
II (Moderately hazardous)
3018
Packaging Group III (minor danger)
pyraclofos
pyraclofos
Pyraclofos
pyraclofos
piraclofos
piraclofos
-
pyraklofos
-
-
-
Record last updated:
23/01/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242