Nuranone (Ref: AI3-38648) |

Last updated: 25/08/2025
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(Also known as: japonilure; Japanese beetle sex pheromone) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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An insect attractant produced by female Japanese beetles used for beetle control |
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Japanese beetles (Popillia japonica) |
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Ornamental and horticultural crops; Turf |
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- |
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Not approved |
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Not applicable |
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No UK approval for use as a plant protection agent |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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A chiral molecule |
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C₁₄H₂₄O₂ |
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CCCCCCCCC=CC1CCC(=O)O1 |
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CCCCCCCC/C=C\[C@H]1CCC(=O)O1 |
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QTGIYXFCSKXKMO-XPSMFNQNSA-N |
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InChI=1S/C14H24O2/c1-2-3-4-5-6-7-8-9-10-13-11-12-14(15)16-13/h9-10,13H,2-8,11-12H2,1H3/b10-9-/t13-/m0/s1 |
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Yes |
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Insecticide; Semiochemical |
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Pheromone |
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>95% |
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- |
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Natural |
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Distrupts mating cycle by used luring males away from females |
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A sex pheromone produced by female Japanese beetles Popillia japonica Newman (Scarabaeidae, Coleoptera) |
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Crop protection |
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Japanese beetles (Popillia japonica) |
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Ornamental and horticultural crops; Turf |
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Suitable for use in all farming systems where approved for use in that country |
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64726-91-6 |
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265-035-8 |
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- |
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116501 |
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6435920 |
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224.34 |
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- |
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(1Z,5R)-5-dec-1-enyltetrahydrofuran-2-one |
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(5R)-5-(1Z)-1-decenyldihydro-2(3H)-furanone |
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- |
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- |
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- |
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Not applicable |
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Not applicable |
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None |
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Not applicable |
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- |
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Oil |
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Current |
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1979, first registered USA |
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- Bag-A-Bug
- BioLure Japanese Beetle Trap
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Usually supplied a a dual scented trap containing food plant extracts to attract female beetles and the pheromone to attact the males. Traps are hung in trees. |
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Nuranone is produced synthetically for commercial products. The production process involves creating (R,Z)-5-(1-decenyl)dihydro-2(3H)-furanone. The synthesis begins relatively simple materials, such as decanal and a furanone derivative. Decanal undergoes a reaction to form an intermediate compound using a catalyst. The intermediate is then coupled with the furanone derivative. This step typically involves a coupling agent to form the desired (R,Z)-5-(1-decenyl)dihydro-2(3H)-furanone. |
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While exact CO₂e values are not published for specific pheromones, some general information is available. The PHERA reported that biotechnological production (e.g. yeast fermentation) of pheromones can reduce GHG emissions by up to 90% compared to traditional chemical synthesis and GHG emissions are typically in the 5 to 10 kg CO₂e per kg of pheromone produced. Other sources suggest that small scale pheromone synthesis typically has emissions in the range 1 – 3 kg CO₂e per kg of pheromone produced. |
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2.00 X 1004 |
Calculated |
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4.3 |
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High |
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Not applicable to this substance |
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Not applicable to this substance |
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Not applicable to this substance |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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Not applicable to this substance |
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None
Terrestrial ecotoxicology |
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HUMAN HEALTH AND PROTECTION |
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Intermediate (class II) |
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> 1.35 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat (aerosol) |
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Since there are no food uses of nuranone, dietary exposure is not expected |
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Unlikely to produce adverse effects in workers |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative |
XNo, known not to cause a problem |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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XNo, known not to cause a problem |
No data found |
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Considered to be non-toxic |
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No information available |
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Not listed (Not listed) |
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nuranone |
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Record last updated: |
25/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |