Bacillus cereus B4 |

Last updated: 24/08/2025
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(Also known as: UFV-62; LysB4) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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A gram-positive bacterium which shows fungicidal activity |
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Seedling rot; Late & early blight; Alternaria solani |
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Tomatoes |
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A rod-shaped, endospore forming, facultative aerobic bacterium |
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Class: Bacilli; Order: Bacillales; Family: Bacillaceae |
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Not approved |
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Not applicable |
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No UK approval for use as a plant protection agent |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Not applicable |
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No |
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Fungicide |
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Micro-organism |
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Natural |
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Induces systemic resistance - produces metabolites that control certain fungi that cause disease in plants. |
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Commonly found in soils, on vegetables and in food |
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Crop protection |
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Seedling rot; Late & early blight; Alternaria solani |
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Tomatoes |
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Suitable for use in all farming systems where approved for use in that country |
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Bacillus cereus B4 |
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Not applicable |
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Not applicable |
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Not applicable |
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BM02 |
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Bacterium |
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Current |
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Commercial production of Bacillus species typically involves large-scale aerobic fermentation. The process begins with selecting a robust strain, often genetically optimised for yield and stability. These bacteria are cultivated in bioreactors under tightly controlled conditions, temperature (usually 30–37 degrees C), pH (neutral to slightly alkaline), and oxygen levels are carefully regulated to maximise growth and productivity. Nutrient-rich media, often containing glucose or other carbon sources, support rapid biomass accumulation. After fermentation, the culture is harvested, and the desired products, such as enzymes or spores, are extracted and purified. |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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Known soil and groundwater metabolites |
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None
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Kanosamine |
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3,4-dihydroxy benzoate |
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2-keto-4-methylthiobutyrate |
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Terrestrial ecotoxicology |
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HUMAN HEALTH AND PROTECTION |
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Not applicable |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative |
XNo, known not to cause a problem |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
?Possibly, status not identified |
Eye irritant |
Phototoxicant |
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XNo, known not to cause a problem |
No data found |
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Some strains of B. cereus can cause food poisoning |
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No information available |
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Not listed (Not listed) |
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Bacillus cereus B4 |
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Record last updated: |
24/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |