Bacillus amyloliquefaciens AT-332 |

Last updated: 24/08/2025
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(Also known as: FZB42; B. amyloliquefaciens FZB42) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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Used as a protectant against a range of economically important air-borne fungal diseases |
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Downy mildew; Late blight; Grey mold |
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Lettuce |
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- |
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The lifecyle has found distinct phases: germination, outgrowth, multiplication and sporulation. It is usually supplied as a light brown powdery material. |
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Class: Bacilli; Order: Bacillales; Family: Bacillaceae |
EC Regulation 1107/2009 (repealing 91/414) |
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Pending |
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Netherlands |
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No |
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Yes |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Not applicable |
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- |
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No |
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Fungicide |
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Micro-organism |
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- |
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- |
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Natural |
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Acts by combining three antifungal pathways: (i) the production of anti-microbial metabolites- antibiotics, (ii) the competitive exclusion/interaction and (iii) the induction of plant systemic resistance or systemic |
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Occurs widely in soils, indigenous to the European region |
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Crop protection |
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Downy mildew; Late blight; Grey mould |
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Lettuce |
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Suitable for use in all farming systems where approved for use in that country |
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- |
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- |
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Bacillus amyloliquefaciens strain AT332 |
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- |
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Not applicable |
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Not applicable |
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Not applicable |
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BM02 |
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- |
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Bacterium |
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Current |
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1998, first isolated |
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Usually supplied as wettable powders |
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Commercial production of Bacillus species typically involves large-scale aerobic fermentation. The process begins with selecting a robust strain, often genetically optimised for yield and stability. These bacteria are cultivated in bioreactors under tightly controlled conditions, temperature (usually 30–37 degrees C), pH (neutral to slightly alkaline), and oxygen levels are carefully regulated to maximise growth and productivity. Nutrient-rich media, often containing glucose or other carbon sources, support rapid biomass accumulation. After fermentation, the culture is harvested, and the desired products, such as enzymes or spores, are extracted and purified. |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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> 1000 |
Eisenia foetida |
Low |
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HUMAN HEALTH AND PROTECTION |
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Not applicable |
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None allocated |
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None allocated |
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None allocated |
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No adverse health risks identified for proposed uses |
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No adverse health risks identified for proposed uses |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative |
XNo, known not to cause a problem |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
?Possibly, status not identified |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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No adverse health effects noted |
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No information available |
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Not listed (Not listed) |
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Bacillus amyloliquefaciens AT-332 |
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Record last updated: |
24/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |