Trimedlure |

Last updated: 25/08/2025
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(Also known as: mediterranean fruit fly pheromone; TML) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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A synthetic analogue of a natural kairomone insect attractant used to control fruit flies |
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Mediterranean fruit flies |
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Citrus crops |
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- |
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- |
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- |
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Not approved |
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Expired |
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No UK approval for use as a plant protection agent |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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- |
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Expired |
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- |
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Yes |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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A complex chiral molecule. The technical material is an isomeric mixture of 8 isomers - 4 trans (A, B1, B2 & C) and 4 cis (V, W, V, Y) forms. Isomer C is the most attractive to Mediterranean fruit flies |
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C₁₂H₂₁ClO₂ |
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CC1CC(CCC1C(=O)OC(C)(C)C)Cl |
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No data |
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WXTJNIRCHYDKBK-UHFFFAOYSA-N |
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InChI=1S/C12H21ClO2/c1-8-7-9(13)5-6-10(8)11(14)15-12(2,3)4/h8-10H,5-7H2,1-4H3 |
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Yes |
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Semiochemical; Insecticide |
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Pheromone |
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- |
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- |
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Synthetic |
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Non-toxic mode of action. Acts as an attractant |
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- |
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- |
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- |
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- |
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- |
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12002-53-8 |
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234-416-0 |
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8348 |
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112603 |
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- |
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232.75 |
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- |
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tert-butyl (+/-)-4(or 5)-chloro-2-methylcyclohexanecarboxylate |
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1,1-dimethylethyl 4(or 5)-chloro-2-methylcyclohexanecarboxylate |
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- |
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- |
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- |
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Not applicable |
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Not applicable |
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UNM |
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Not applicable |
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- |
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Water-white liquid |
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Current |
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2001, first registration USA |
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- Trimedlure Magnet Plug (BF L076)
- FT Trimedlure
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Usually supplied into slow release formulations |
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- |
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While exact CO₂e values are not published for specific pheromones, some general information is available. The PHERA reported that biotechnological production (e.g. yeast fermentation) of pheromones can reduce GHG emissions by up to 90% compared to traditional chemical synthesis and GHG emissions are typically in the 5 to 10 kg CO₂e per kg of pheromone produced. Other sources suggest that small scale pheromone synthesis typically has emissions in the range 1 – 3 kg CO₂e per kg of pheromone produced. |
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1000 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
Moderate |
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Not applicable |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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3.98 X 1004 |
Calculated |
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4.6 |
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High |
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1 |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
Slightly mobile |
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2625 |
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Estimated |
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- |
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- |
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- |
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None
Terrestrial ecotoxicology |
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4556 |
Rat |
Low |
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- |
- |
- |
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- |
- |
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- |
- |
- |
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2000 |
Colinus virginianus |
Moderate |
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9.6 |
Oncorhynchus mykiss |
Moderate |
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Toxic |
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HUMAN HEALTH AND PROTECTION |
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High (class III) |
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4556 |
Rat |
Low |
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2025 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rabbit |
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2.9 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat |
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Carcinogen |
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Endocrine disruptor |
No data found |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
XNo, known not to cause a problem |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
No data found |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
Eye irritant |
Phototoxicant |
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?Possibly, status not identified |
No data found |
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No further information available |
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No information available |
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Health: H315, H319 |
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Not listed (Not listed) |
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trimedlure |
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trimedlure |
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Trimedlur |
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trimedlure |
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trimedlure |
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trimedlure |
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- |
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trimedlur |
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Record last updated: |
25/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |