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propamocarb (Ref: SN 39744)
** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for propamocarb

Description: A fungicide for specific control of Phycomycetes and effective against Phytophthora spp. and Pythium spp. Normally used as the hydrochloride salt.

Example pests controlled: Late blight; Root rot; Damping off; Downy mildew (Bremia lactucae); Mildew

Example applications: Turf; Ornamentals; Tobacco; Vegetables; Potatoes; Strawberries; Cucumbers; Tomato; Lettuce

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1978, discovered

EC Regulation 1107/2009 (repealing 91/414):

Status Approved
Dossier rapporteur/co-rapporteur Portugal/Belgium
Date inclusion expires 30/07/2019
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Chemical structure: Click here for further information on the general chemical status information used on this site

Isomerism -
Chemical formula C9H20N2O2
Canonical SMILES CCCOC(=O)NCCCN(C)C
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) WZZLDXDUQPOXNW-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C9H20N2O2/c1-4-8-13-9(12)10-6-5-7-11(2)3/h4-8H2,1-3H3,(H,10,12)
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site

Pesticide type Fungicide
Substance group Carbamate
Minimum active substance purity -
Known relevant impurities -
Substance origin Synthetic
Mode of action Systemic, with protective action absorbed by roots and leaves and translocated. Lipid synthesis inhibitor.
CAS RN 24579-73-5
EC number -
CIPAC number 399
US EPA chemical code 119302
PubChem CID 32490
Molecular mass (g mol-1) 188.3
PIN (Preferred Identification Name) propyl [3-(dimethylamino)propyl]carbamate
IUPAC name propyl 3-(dimethylamino)propylcarbamate
CAS name propyl (3-(dimethylamino)propyl)carbamate
Other status information -
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 28
Examples of recorded resistance -
Physical state -
Related substances & organisms

Formulations:

Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Bayer CropScience
Example products using this active
  • Banol
  • Tattoo C
  • Dynone
  • Filex
  • Proplant
UK LERAP status Buffer probably required in UK - see product label
Formulation and application details Usually formulated as an aqueous concentrate using the hydrochloride salt.


ENVIRONMENTAL FATE

for propamocarb

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 900000 L3 High
Solubility - In organic solvents at 20oC (mg l-1) 883000 L3 - Hexane -
933000 L3 - Methanol -
937000 L3 - Dichloromethane -
921000 L3 - Acetone -
Melting point (oC) - - -
Boiling point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) 100 Q2 -
Octanol-water partition coefficient at pH 7, 20oC P 6.92 X 1000 Calculated -
Log P 0.84 L3 Low
Bulk density (g ml-1)/Specific gravity 0.963 L3 -
Dissociation constant (pKa) at 25oC 9.5 L3 -
Note: Strong base
Vapour pressure at 20oC (mPa) 730 L3 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 1.5 X 10-04 L3 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index - - -
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value - - -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - - -
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:

Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 14 A4 Non-persistent
DT50 (lab at 20oC) 14 P4 Non-persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note: -
Dissipation rate RL50 on plant matrix Value 4.75 R3 -
Note Cabbage leaves, n=1
Dissipation rate RL50 on and in plant matrix Value 8.5 R4 -
Note RL50 range 8.2-9.1, ginseng root, stems & leaves, n=3
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value - - -
Note -
Water-sediment DT50 (days) - - -
Water phase only DT50 (days) - - -

Soil adsorption and mobility:

Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - - -
Koc -
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -


ECOTOXICOLOGY

for propamocarb

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk Q3 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) - - -
Mammals - Short term dietary NOEL (mg kg-1) - - -
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) - - -
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 96.8 F4 Cyprinodon variegatus Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 106 F4 Daphnia magna Low
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 104.7 F4 Americamysis bahia Low
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 301 F4 Scenedesmus quadricauda Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 100 A5 as the hydrochloride salt Low
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 84 A5 as the hydrochloride salt Moderate
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 500 as EC50 hydrochloride salt
A4 Aphidius rhopalosiphi
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 360 >, as EC50 hydrochloride salt
A4 Typhlodromus pyri
-
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for propamocarb

General:

Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) - - -
Mammals - Dermal LD50 (mg kg-1 body weight) - - -
Mammals - Inhalation LC50 (mg l-1) - - -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.29 A5 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 1.0 A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.29 A5 -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public -
Occupational -
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:

Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

A0; B0; C0; D0; E0

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Possible weak skin sensitiser
Endocrine issues - Weak increase of aromatase activity and estrogen production
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:

Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not flammable or explosive
CLP classification 2013 Health: H302
EC Risk Classification Click here to view information omn the EU risk phrases Xn - Harmful: R22
EC Safety Classification Click here to view information omn the EU safety phrases -
WHO Classification U - Unlikely to present an acute hazard
UN Number -
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for propamocarb

Language Name
English propamocarb
French propamocarbe
German Propamocarb
Danish propamocarb
Italian propamocarb
Spanish propamocarb
Greek -
Slovenian -
Polish chlorowodorek
Swedish propamokarb
Hungarian propamokarb
Dutch propamocarb

Record last updated: Friday 03 May 2019
Contact: aeru@herts.ac.uk
© University of Hertfordshire