Butamifos (Ref: S-2846)
Last updated: 01/09/2023
(Also known as: metacrefos)
Butamifos is an organophosphate herbicide used to control annual and graminaceous weeds. It has a low aqueous solubility but other environmental fate related data is scarce. Generally, butamifos is moderately toxic to biodiversity. It is also moderately toxic to mammals if ingested and is thought to be an acetyl cholinesterase inhibitor.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An organophosphate herbicide used to control annual and graminaceous weeds
Fathen; Groundsel; Wild oats; Wild canary grass; Brome; Crowsfoot grass; Nettles
Lawns; Rice; Vegetables including beans, onions; Cereals including barley, wheat; Beet crops; Strawberries
-
-
-
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
Butamifos is a chiral molecule. The technical material is a mixture of the R- and S-isomers.
C₁₃H₂₁N₂O₄PS
CCC(C)NP(=S)(OCC)OC1=C(C=CC(=C1)C)[N+](=O)[O-]
No data
OEYOMNZEMCPTKN-UHFFFAOYSA-N
InChI=1S/C13H21N2O4PS/c1-5-11(4)14-20(21,18-6-2)19-13-9-10(3)7-8-12(13)15(16)17/h7-9,11H,5-6H2,1-4H3,(H,14,21)
Yes
Herbicide
Organophosphate herbicide
-
-
Synthetic
Microtubule assembly inhibition. Non-systemic, selective
36335-67-8
609-231-7
None allocated
Not listed
37419
No data found
332.36
(E)-[O-ethyl O-(5-methyl-2-nitrophenyl) (2E)-butan-2-ylphosphoramidothioate]
(RS)-{O-ethyl O-6-nitro-m-tolyl [(RS)-sec-butyl]phosphoramidothioate}
O-ethyl O-(5-methyl-2-nitrophenyl) (1-methylpropyl)phosphoramidothioate
PAN Bad Actor Chemical
-
K1
3
Not applicable
Not applicable
-
Liquid
Cremart Hercules 26905 Tufler
Usually supplied as emulsifiable concentrates and granules
6.19
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Low
-
-
-
25
-
422
-
-
-
-
-
-
-
4.17 X 1004
Calculated
-
4.62
High
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Soil adsorption and mobility
-
-
-
Cannot be calculated
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-
-
-
-
-
-
-
-
-
-
-
-
-
None
Terrestrial ecotoxicology
630
Rat
Moderate
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4.1
Oncorhynchus mykiss
Moderate
-
-
-
1.56
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Daphnia magna
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0.025
Selenastrum capricornutum
Moderate
-
-
-
-
-
-
-
-
-
HUMAN HEALTH AND PROTECTION
High (class III)
-
-
630
Rat
Moderate
5000
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
-
> 1.2
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
List I
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-
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EU MRL pesticide database 
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-
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-
-
Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
✓Yes, known to cause a problem
?Possibly, status not identified
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
Harmful if swallowed
No information available
-
II (Moderately hazardous)
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-
-
butamifos
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Record last updated:
01/09/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242